Browse our S1PR2 Proteins (S1PR2)

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Sphingosine-1-Phosphate Receptor 2 Proteins (S1PR2)
On are 3 Sphingosine-1-Phosphate Receptor 2 (S1PR2) Proteins from 2 different suppliers available. Additionally we are shipping S1PR2 Antibodies (61) and S1PR2 Kits (13) and many more products for this protein. A total of 84 S1PR2 products are currently listed.
1100001A16Rik, AGR16, EDG-5, Edg5, Gpcr13, GPCR18, H218, LPb2, S1P2, snGPCR18
list all proteins Gene Name GeneID UniProt
S1PR2 9294 O95136
S1PR2 14739 P52592
Rat S1PR2 S1PR2 29415 P47752

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Human Sphingosine-1-Phosphate Receptor 2 (S1PR2) interaction partners

  1. S1PR2 mediates Rho activation in normal cells neighboring RasV12-transformed cells.

  2. Sphingosine 1-phosphate-induced IL-8 (show IL8 Proteins) gene expression is mainly regulated via S1PR(1 (show S1PR1 Proteins)), and its secretion is regulated through S1PR(2) receptor subtype.

  3. S1PR2 is repressed by FOXP1 (show FOXP1 Proteins) in activated B-cell and germinal center B-cell DLBCL cell lines with aberrantly high FOXP1 (show FOXP1 Proteins) levels; S1PR2 expression is further inversely correlated with FOXP1 (show FOXP1 Proteins) expression in 3 DLBCL patient cohorts.

  4. LXR-alpha (show NR1H3 Proteins) might downregulate S1PR2 expression via miR (show MLXIP Proteins)-130a-3p in quiescent HUVECs. Stimulation of TNF-alpha (show TNF Proteins) attenuates the activity of LXR-alpha (show NR1H3 Proteins) and results in enhanced S1PR2 expression.

  5. S1PR2 plays a critical role in TCA-induced COX-2 expression and CCA (show FBN2 Proteins) growth and may represent a novel therapeutic target for CCA (show FBN2 Proteins).

  6. both S1PR1 (show S1PR1 Proteins) and S1PR2 play a pivotal role in hyperglycemia-induced EC dysfunction and endothelial injury by reducing and enhancing the production of oxidative stress.

  7. AB1 displayed potency at least equivalent to JTE-013 in affecting signaling molecules downstream of S1P2.

  8. Activation of S1PR2-calcium influx-RhoA (show RHOA Proteins)/ROCK dominates the high-dose S1P (show MBTPS1 Proteins)-induced endothelial monolayer hyperpermeability response.

  9. Data show that sphingosine kinase SphK1 (show SPHK1 Proteins) and sphingosine-1-phosphate (S1P (show MBTPS1 Proteins)) receptors S1P1 (show S1PR1 Proteins), S1P2, S1P3 (show S1PR3 Proteins), and S1P5 (show S1PR5 Proteins) were expressed from primary, up to recurrent and secondary glioblastomas, with sphingosine kinase SphK2 (show SPHK2 Proteins) levels were highest in primary tumors.

  10. Data indicate that sphingosine 1-phosphate (S1P (show MBTPS1 Proteins)) and hepatocyte growth factor (HGF (show HGF Proteins)) induced transloaction of integrin beta4, S1P (show MBTPS1 Proteins) receptors S1PR2 and S1PR3 (show S1PR3 Proteins) to endothelial cell membrane caveolin-enriched microdomains (CEMs).

Mouse (Murine) Sphingosine-1-Phosphate Receptor 2 (S1PR2) interaction partners

  1. Results provide evidence that S1PR2 plays an essential role in modulating proinflammatory cytokine production and osteoclastogenesis.

  2. activation of S1P2 with a selective receptor agonist increases cell viability and reduces cisplatin-mediated cell death by reducing ROS (show ROS1 Proteins). Cumulatively, these results suggest that S1P2 may serve as a therapeutic target for attenuating cisplatin-mediated ototoxicity.

  3. S1P2 receptor is a key signaling molecule in the S1Pdependent inhibition of adipogenic differentiation.

  4. S1PR2, as a critical receptor in macrophages, impairs phagocytosis and antimicrobial defense in the pathogenesis of sepsis.

  5. These results suggest that S1PR2 and CXCR5 (show CXCR5 Proteins) cooperatively regulate localization of Tfh cells in GCs (show UGCG Proteins) to support GC responses

  6. The sphingolipid receptor S1PR2 is a receptor for Nogo-a (show RTN4 Proteins) repressing synaptic plasticity.

  7. S1PR2 expression was increased in disease-susceptible regions of the CNS of female SJL EAE mice compared with their male counterparts.

  8. IL-6 (show IL6 Proteins) increased the number of osteoclast precursor cells in tibial bone marrow via up-regulating S1PR2, thus playing a crucial role in systemic bone loss induced by inflammation.

  9. Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase (show NOS3 Proteins) in mice.

  10. Data show that two S1P (show S1PR1 Proteins) receptors, S1P2 and S1P3 (show S1PR3 Proteins), are collectively essential mediators of eyelid closure during murine development.

S1PR2 Protein Profile

Protein Summary

This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation

Alternative names and synonyms associated with S1PR2

  • sphingosine-1-phosphate receptor 2 (S1PR2)
  • sphingosine-1-phosphate receptor 2 (S1pr2)
  • 1100001A16Rik protein
  • AGR16 protein
  • EDG-5 protein
  • Edg5 protein
  • Gpcr13 protein
  • GPCR18 protein
  • H218 protein
  • LPb2 protein
  • S1P2 protein
  • snGPCR18 protein

Protein level used designations for S1PR2

sphingosine-1-phosphate receptor 2 , sphingosine 1-phosphate receptor 2-like , S1P receptor 2 , S1P receptor EDG5 , S1P receptor Edg-5 , endothelial differentiation G-protein coupled receptor 5 , endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 , sphingosine 1-phosphate receptor 2 , sphingosine 1-phosphate receptor Edg-5 , G-protein coupled receptor 13 , lysophospholipid receptor B2 , sphingosine-1-phosphate receptor S1P(2) , AGR16 , G-protein coupled receptor H218 , S1P2

100392405 Callithrix jacchus
100435839 Pongo abelii
100610932 Pan troglodytes
9294 Homo sapiens
14739 Mus musculus
29415 Rattus norvegicus
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