Browse our SNAP-Associated Protein Proteins (SNAPIN)

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SNAP-Associated Protein Proteins (SNAPIN)
On are 14 SNAP-Associated Protein (SNAPIN) Proteins from 8 different suppliers available. Additionally we are shipping SNAP-Associated Protein Antibodies (42) and SNAP-Associated Protein Kits (8) and many more products for this protein. A total of 68 SNAP-Associated Protein products are currently listed.
25kDa, AA407989, AV026596, Bloc1s7, BLOS7, si:dkey-222b8.2, Snap25bp, Snapap, SNAPIN
list all proteins Gene Name GeneID UniProt
SNAPIN 23557 O95295
SNAPIN 20615 Q9Z266
SNAPIN 295217 P60192

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SNAP-Associated Protein Proteins (SNAPIN) by Origin

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Top referenced SNAP-Associated Protein Proteins

  1. Human SNAPIN Protein expressed in Escherichia coli (E. coli) - ABIN666875 : Chheda, Ashery, Thakur, Rettig, Sheng: Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complex. in Nature cell biology 2001 (PubMed)
    Show all 2 references for 666875

More Proteins for SNAP-Associated Protein Interaction Partners

Human SNAP-Associated Protein (SNAPIN) interaction partners

  1. Taken together, these results suggest that Snapin, the pUL130 interacting protein, has a role in modulating HCMV DNA synthesis.

  2. Disruption of Snapin-PKR2 (show PROKR2 Proteins) interaction did not affect PKR2 (show PROKR2 Proteins) signaling, but increased the ligand-induced degradation, implying a role of Snapin in the trafficking of PKR2 (show PROKR2 Proteins).

  3. Authors propose that Snapin connects chlamydial inclusions with the microtubule network by interacting with both Chlamydia psittaci IncB and dynein.

  4. Snapin, a SNAP (show NAPA Proteins)-25 (synaptosomal-associated protein-25 (show SNAP25 Proteins)) interacting protein, interacts with LRRK2 (show LRRK2 Proteins).

  5. Our findings reveal that Atg14L, previously considered to be solely a Beclin 1 (show BECN1 Proteins)-binding autophagy protein, plays a novel role in the late stage of endocytic trafficking in conjunction with Snapin

  6. These observations identify Snapin as a novel endogenous TLR2 ligand in rheumatoid arthritis, and thus support a role for persistent TLR2 signalling in pathogenesis.

  7. These results suggest that Snapin may play a key role in regulating the cellular localization of human cytomegalovirus UL70, leading to modulation of viral DNA synthesis and progeny production.

  8. PKA-dependent phosphorylation of snapin increases interaction among insulin (show INS Proteins) secretory vesicle-associated proteins, thereby potentiating glucose-stimulated insulin (show INS Proteins) secretion.

  9. results suggest that RGS7 could play a role in synaptic vesicle exocytosis through its interaction with snapin

  10. EBAG9 (show EBAG9 Proteins) and Snapin have roles in controlling exocytosis processes

Mouse (Murine) SNAP-Associated Protein (SNAPIN) interaction partners

  1. Snapin-dysbindin interaction regulates synaptic vesicle positional priming through BLOC-1/AP-3-dependent sorting.

  2. Snapin reduces APP (show APP Proteins) processing by enhancing BACE1 (show BACE Proteins) lysosomal degradation.

  3. Transmembrane prostatic acid phosphatase (show ACPP Proteins) (TMPAP) interacts with snapin and deficient mice develop prostate adenocarcinoma.

  4. Snapin accelerates exocytosis at low intracellular calcium concentration in mouse chromaffin cells.

  5. Snapin-dynein coupling is one of the primary mechanisms driving BDNF (show BDNF Proteins)-TrkB (show NTRK2 Proteins) retrograde transport, thus providing mechanistic insights into the regulation of neuronal growth and survival.

  6. AC6 (show ADCY6 Proteins)-mediated inhibition of neurite outgrowth was reversed by the overexpression of Snap25 (show SNAP25 Proteins) or a Snapin mutant that could not be phosphorylated.

  7. Snapin has a role in regulating autophagy-lysosomal function

  8. PKA-dependent phosphorylation of snapin increases interaction among insulin (show INS Proteins) secretory vesicle-associated proteins, thereby potentiating glucose-stimulated insulin (show INS Proteins) secretion.

  9. Snapin deficiency leads to reduced cell density in cortical plates, apoptotic death in the cortex & third ventricle, enhanced membrane-bound LC3 (show MAP1LC3A Proteins)-II staining, and accumulation of polyubiquitinated proteins in the cortex and hippocampus in knockout mice

  10. highlights new mechanistic insights into how Snapin-intermediate chain coordinates retrograde transport and late endosomal-lysosomal trafficking critical for autophagy-lysosomal function, and thus neuronal homeostasis.

SNAP-Associated Protein (SNAPIN) Protein Profile

Protein Summary

The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SNAP-Associated Protein (SNAPIN)

  • SNAP-associated protein (SNAPIN)
  • SNAP-associated protein (snapin)
  • SNAP-associated protein (Snapin)
  • 25kDa protein
  • AA407989 protein
  • AV026596 protein
  • Bloc1s7 protein
  • BLOS7 protein
  • si:dkey-222b8.2 protein
  • Snap25bp protein
  • Snapap protein
  • SNAPIN protein

Protein level used designations for SNAPIN

SNAP-associated protein , SNARE-associated protein Snapin , BLOC-1 subunit 7 , SNAP-25-binding protein , SNARE associated protein snapin , biogenesis of lysosomal organelles complex-1, subunit 7 , biogenesis of lysosome-related organelles complex 1 subunit 7 , synaptosomal-associated protein 25-binding protein , synaptosomal-associated protein 25 binding protein , synaptosomal-associated protein, 25 kDa, binding protein

490456 Canis lupus familiaris
496040 Xenopus laevis
511816 Bos taurus
567959 Danio rerio
738328 Pan troglodytes
100145066 Xenopus (Silurana) tropicalis
23557 Homo sapiens
20615 Mus musculus
295217 Rattus norvegicus
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