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Browse our CD80 Proteins (CD80)

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CD80 Proteins (CD80)
On are 36 CD80 Proteins from 10 different suppliers available. Additionally we are shipping CD80 Antibodies (585) and CD80 Kits (25) and many more products for this protein. A total of 664 CD80 products are currently listed.
B7, B7-1, B7.1, B71, BB1, CD8, Cd28l, CD28LG, CD28LG1, LAB7, Leu2, Ly-53, Ly53, MAL, MIC17, p32, TSA1
list all proteins Gene Name GeneID UniProt
CD80 100360171  
CD80 12519 Q00609
CD80 25408  

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CD80 Proteins (CD80) by Origin

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Top referenced CD80 Proteins

  1. Mouse (Murine) CD80 Protein expressed in CHO Cells - ABIN2666531 : Czuczman, Thall, Witzig, Vose, Younes, Emmanouilides, Miller, Moore, Leonard, Gordon, Sweetenham, Alkuzweny, Finucane, Leigh: Phase I/II study of galiximab, an anti-CD80 antibody, for relapsed or refractory follicular lymphoma. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005 (PubMed)
    Show all 6 references for ABIN2666531

  2. Human CD80 Protein expressed in Human Cells - ABIN2003256 : Freeman, Gray, Gimmi, Lombard, Zhou, White, Fingeroth, Gribben, Nadler: Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7. in The Journal of experimental medicine 1991 (PubMed)
    Show all 5 references for ABIN2003256

  3. Cynomolgus CD80 Protein expressed in Human Cells - ABIN2010065 : Lanier, OFallon, Somoza, Phillips, Linsley, Okumura, Ito, Azuma: CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
    Show all 5 references for ABIN2010065

  4. Mouse (Murine) CD80 Protein expressed in Human Cells - ABIN2007806 : Suvas, Singh, Sahdev, Vohra, Agrewala: Distinct role of CD80 and CD86 in the regulation of the activation of B cell and B cell lymphoma. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN2007806

  5. Cynomolgus CD80 Protein expressed in HEK-293 Cells - ABIN2180839 : Bhatia, Edidin, Almo, Nathenson: Different cell surface oligomeric states of B7-1 and B7-2: implications for signaling. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 2 references for ABIN2180839

  6. Human CD80 Protein expressed in HEK-293 Cells - ABIN2180841 : Khan, Ghousunnissa, Jegadeeswaran, Thiagarajan, Hasnain, Mukhopadhyay: Anti-B7-1/B7-2 antibody elicits innate-effector responses in macrophages through NF-kappaB-dependent pathway. in International immunology 2007 (PubMed)
    Show all 2 references for ABIN2180841

More Proteins for CD80 Interaction Partners

Cow (Bovine) CD80 interaction partners

  1. Northern analysis revealed CD80 and CD86 (show CD86 Proteins) mRNAs in luteal tissue, with greatest steady-state concentrations at midcycle

Human CD80 interaction partners

  1. Genetic interaction of CD80 and ALOX5AP (show ALOX5AP Proteins) was observed in systemic lupus erythematosus in Asian populations.

  2. Inhibitory Profile of Liver CD68 (show CD68 Proteins)+ Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 (show CD274 Proteins) but Not CD86 (show CD86 Proteins) Expression

  3. Triple costimulation via CD80, 4-1BB (show TNFRSF9 Proteins), and CD83 (show CD83 Proteins) ligand elicits the long-term growth of Vgamma9Vdelta2 T cells in low levels of IL-2 (show IL2 Proteins).

  4. B7-1 is not induced in podocytes from patients with minimal change disease or focal segmental glomerulosclerosis.

  5. In the present study, we investigated the prognostic significance of the expression of three genes in the PD-L1 (show CD274 Proteins) pathway, including PD-L1 (show CD274 Proteins), B7.1 and PD-1 (show PDCD1 Proteins), in three independent bladder cancer datasets in the Gene Expression Omnibus database.

  6. SNP rs1599795 in CD80 3'-UTR, through disrupting the regulatory role of miR (show MLXIP Proteins)-132-3p, miR (show MLXIP Proteins)-212-3p, and miR (show MLXIP Proteins)-361-5p in CD80 expression, contributed to the occurrence of gastric cancer.

  7. Meningococcal capsular polysaccharide-loaded vaccine nanoparticles induce expression of CD80.

  8. These findings reveal the distinct but complementary roles of CD80 and CD86 (show CD86 Proteins) IgV and IgC domains in T cell activation.

  9. Five functional polymorphisms of B7/CD28 (show CD28 Proteins) co-signaling molecules alter susceptibility to colorectal cancer.

  10. Expression of costimulatory molecules CD80/86 is an absolute requirement for efficient CD8 (show CD8A Proteins) T cell priming by adenoviral vectors.

Mouse (Murine) CD80 interaction partners

  1. Meningococcal capsular polysaccharide-loaded vaccine nanoparticles induce expression of CD80.

  2. The genetic inactivation of B7.1/B7.2 (show CD86 Proteins) deteriorates obesity-related liver steatosis and metabolic dysregulation, likely a result of the intrinsic absence of Tregs in these mice, rendering DKO mice a novel murine model of NASH (show SAMSN1 Proteins).

  3. These results indicate that B7H1 (show CD274 Proteins)/CD80 interaction augments Tcon cell proliferation, IL-2 (show IL2 Proteins) production, and expression of PD-1 (show PDCD1 Proteins), which leads to increased apoptosis

  4. CD28 (show CD28 Proteins)-CD80 interactions control regulatory T cell motility and immunological synapse formation.

  5. demonstrates that the simultaneous silencing of CD40 (show CD40 Proteins) and CD80 genes has synergistic effects in preventing allograft rejection, and may therefore have therapeutic potential in clinical transplantation

  6. cardiomyocytes can express CD80; this expression pattern can resist CTL-mediated lysis through CTLA-4 (show CTLA4 Proteins) pathway

  7. data show an important role of the adaptive immune system, in particular T cell CD80/86 costimulation molecules, in the physiological regulation of bone resorption and preservation of bone mass

  8. CD80 and CD86 (show CD86 Proteins) costimulatory molecules regulate OT-II CD4 (show CD4 Proteins)(+) T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice

  9. The need for additional immune suppression in the intestine reflects commensal microbe-driven T-cell activation through the accessory costimulation molecules ICOSL (show ICOSLG Proteins) and OX40L (show TNFSF4 Proteins) in B7 deprived mice.

  10. demonstrate that subcategorizing memory B cells on the basis of their expression of CD80 and PD-L2 (show PDCD1LG2 Proteins)

CD80 Protein Profile

Protein Summary

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

Alternative names and synonyms associated with CD80

  • CD80 molecule (CD80)
  • CD8a molecule (CD8A)
  • CD80 antigen (Cd80)
  • Cd80 molecule (Cd80)
  • B7 protein
  • B7-1 protein
  • B7.1 protein
  • B71 protein
  • BB1 protein
  • CD8 protein
  • Cd28l protein
  • CD28LG protein
  • CD28LG1 protein
  • LAB7 protein
  • Leu2 protein
  • Ly-53 protein
  • Ly53 protein
  • MAL protein
  • MIC17 protein
  • p32 protein
  • TSA1 protein

Protein level used designations for CD80 Proteins (CD80)

CD80 antigen , T-lymphocyte activation antigen CD80 , CD8 antigen, alpha polypeptide (p32) , Leu2 T-lymphocyte antigen , OKT8 T-cell antigen , T cell co-receptor , T-cell antigen Leu2 , T-cell surface glycoprotein CD8 alpha chain , T-lymphocyte differentiation antigen T8/Leu-2 , T8 T-cell antigen , B7 protein , activation B7-1 antigen , B-lymphocyte activation antigen B7 , CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) , CTLA-4 counter-receptor B7.1 , costimulatory factor CD80 , costimulatory molecule variant IgV-CD80 , B7-1 protein , T-cell co-stimulatory protein B7-1 , Cd80 a rat homolog of the human CD28/CTLA - 4 ligand (B7-1)

407131 Bos taurus
100360171 Homo sapiens
12519 Mus musculus
941 Homo sapiens
768950 Gallus gallus
403765 Canis lupus familiaris
25408 Rattus norvegicus
100009377 Oryctolagus cuniculus
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