Browse our anti-STIM1 (STIM1) Antibodies

Full name:
anti-Stromal Interaction Molecule 1 Antibodies (STIM1)
On www.antibodies-online.com are 155 Stromal Interaction Molecule 1 (STIM1) Antibodies from 24 different suppliers available. Additionally we are shipping STIM1 Proteins (18) and STIM1 Kits (2) and many more products for this protein. A total of 185 STIM1 products are currently listed.
Synonyms:
D11S4896E, GOK, MGC76045, MGC154748, si:ch211-112l17.2, si:dkey-24p1.5, SIM, Stim1, TAM
list all antibodies Gene Name GeneID UniProt
STIM1 6786 Q13586
STIM1 20866 P70302
STIM1 361618 P84903

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Top referenced anti-STIM1 Antibodies

  1. Human Monoclonal STIM1 Primary Antibody for IF, WB - ABIN968271 : Hu, Lee, Connors, Johnson, Burn, Su, Landes, Feinberg: A 2.5-Mb transcript map of a tumor-suppressing subchromosomal transferable fragment from 11p15.5, and isolation and sequence analysis of three novel genes. in Genomics 1998 (PubMed)
    Show all 5 references for 968271

  2. Human Polyclonal STIM1 Primary Antibody for EIA, IHC (p) - ABIN954978 : Byun, Abhyankar, Lelarge, Plancoulaine, Palanduz, Telhan, Boisson, Picard, Dewell, Zhao, Jouanguy, Feske, Abel, Casanova: Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma. in The Journal of experimental medicine 2010 (PubMed)
    Show all 4 references for 954978

  3. Human Monoclonal STIM1 Primary Antibody for ICC, IF - ABIN188961 : Williams, Manji, Parker, Hancock, Van Stekelenburg, Eid, Senior, Kazenwadel, Shandala, Saint, Smith, Dziadek: Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins. in The Biochemical journal 2001 (PubMed)
    Show all 3 references for 188961

  4. Cow (Bovine) Polyclonal STIM1 Primary Antibody for ICC, IF - ABIN258795 : Meuchel, Stewart, Smelter, Abcejo, Thompson, Zaidi, Martin, Prakash: Neurokinin-neurotrophin interactions in airway smooth muscle. in American journal of physiology. Lung cellular and molecular physiology 2011 (PubMed)
    Show all 2 references for 258795

  5. Human Monoclonal STIM1 Primary Antibody for IF, WB - ABIN396503 : Verma, Hoffmann, Kumar, Huang, Roe, Nguyen-Wu, Hashimoto, Hoffmann: Selenoprotein K knockout mice exhibit deficient calcium flux in immune cells and impaired immune responses. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)

  6. Human Monoclonal STIM1 Primary Antibody for IF, IHC (p) - ABIN2476609 : Varga-Szabo, Braun, Kleinschnitz, Bender, Pleines, Pham, Renné, Stoll, Nieswandt: The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction. in The Journal of experimental medicine 2008 (PubMed)

More Antibodies against STIM1 Interaction Partners

Pig (Porcine) Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. Downregulation of STIM1 levels in oocytes by siRNA completely inhibited the repetitive Ca(2 (show CA2 Antibodies)+) signal triggered by the fertilizing sperm.

  2. findings suggest that in oocytes, STIM1 serves as a sensor of Ca(2 (show CA2 Antibodies)+) store content that after store depletion moves to the plasma membrane to stimulate store-operated Ca(2 (show CA2 Antibodies)+) entry

  3. STIM1 plays role in PAR1 (show F2R Antibodies)-mediated Ca2 (show CA2 Antibodies)+ influx and Ca2 (show CA2 Antibodies)+-dependent NO production in endothelial cells; DNA sequence alignment of porcine and human STIM1

Zebrafish Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. STIM1 is localized to the cleavage furrow during cytokinesis of the first and second cell division cycles in zebrafish embryos.

Xenopus laevis Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. STIM1/TRPC1 (show TRPC1 Antibodies)-dependent store-operated Ca2 (show CA2 Antibodies)+ entry plays an essential role in generating spatiotemporal Ca2 (show CA2 Antibodies)+ signals that mediate guidance responses of nerve growth cones.

Silk Worm Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. STIM1 and Orai1 (show ORAI1 Antibodies) are essential components of the signal transduction cascade that regulates sex pheromone production.

Human Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. RASSF4 (show RIN2 Antibodies) controls store operated calcium entry and endoplasmic reticulum-plasma membrane junctions through ARF6 (show ARF6 Antibodies)-dependent regulation of PM PI(4,5)P2 levels, pivotal for a variety of physiological processes.

  2. conformational changes in STIM1 upon calcium release

  3. STIM1-induced Ca(2 (show CA2 Antibodies)+) signaling activates Pyk2 (show PTK2B Antibodies) to inhibit the interaction of VE-PTP (show PTPRB Antibodies) and VE-cadherin (show CDH5 Antibodies) and hence increase endothelial permeability.

  4. Elevated Orai1 (show ORAI1 Antibodies) and STIM1 expressions upregulate MACC1 (show MACC1 Antibodies) expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  5. It represents as a target of cisplatin and blockade of Stim1-mediated Ca(2 (show CA2 Antibodies)+) entry may be a useful strategy to improve the efficacy of cisplatin to treat osteosarcoma.

  6. STIM1L and TRPC1 (show TRPC1 Antibodies)/4 are working together in myotubes to ensure efficient store refilling and a proper differentiation program.

  7. SARAF (show TMEM66 Antibodies) modulates TRPC1 (show TRPC1 Antibodies), but not TRPC6 (show TRPC6 Antibodies), channel function in a STIM1-independent manner

  8. What is less clear is how the spatial and temporal spread of intracellular Ca(2 (show CA2 Antibodies)+) is shaped and regulated by differential expression of the individual SOCE genes and their splice variants, their heteromeric combinations and pre- and posttranslational modifications. This review focuses on principle mechanisms regulating expression, splicing, and targeting of Ca(2 (show CA2 Antibodies)+) release-activated Ca(2 (show CA2 Antibodies)+) (CRAC) channels.

  9. The focus is on the activation of the STIM proteins, the subsequent coupling of STIM1 to Orai1 (show ORAI1 Antibodies), and the consequent structural rearrangements that gate the Orai channels into the open state to allow Ca(2 (show CA2 Antibodies)+)permeation into the cell. [review]

  10. Mutations in the STIM1 and ORAI1 (show ORAI1 Antibodies) genes cause calcium dyshomeostasis in tubular aggregate myopathy. (Review)

Cow (Bovine) Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. STIM1 and STIM2 (show Stim2 Antibodies) are expressed in bovine aortic endothelial cells and they both interact with IP3R-1 (show ITPR1 Antibodies).

Mouse (Murine) Stromal Interaction Molecule 1 (STIM1) interaction partners

  1. data indicate that STIM1 overexpression in neurons in the brain perturbs metabotropic glutamate (show GRIN1 Antibodies) receptor signaling, leading to impairments in long-term depression and alterations in animal behavior

  2. Ca(2 (show CA2 Antibodies)+) entry serves critical cellular functions in virtually every cell type, and appropriate regulation of Ca(2 (show CA2 Antibodies)+) in neurons is essential for proper function.

  3. STIM1-induced Ca(2 (show CA2 Antibodies)+) signaling activates Pyk2 (show PTK2B Antibodies) to inhibit the interaction of VE-PTP (show PTPRB Antibodies) and VE-cadherin (show CDH5 Antibodies) and hence increase endothelial permeability.

  4. suggests that STIM1 is a multifunctional signaling effector that participates in the control of membrane excitability and Ca(2 (show CA2 Antibodies)+) signaling events in beta-cells

  5. vascular smooth muscle STIM1 plays a crucial role in the development of hypertension and associated cardiovascular pathologies.

  6. Data show that the STIM1 Ksp (Eg5 (show KIF11 Antibodies))-cre knockout mice produced more urine compared to control.

  7. We conclude that STIM1 has an unexpected function in the heart where it alters communication between the sarcolemma and sarcoplasmic reticulum resulting in greater Ca(2 (show CA2 Antibodies)+) flux and a leaky SR compartment.

  8. Stim1 silencing prevented mTOR (show FRAP1 Antibodies) complex 2 phosphorylation of Akt (show AKT1 Antibodies)(S473) via a direct interaction between STIM1 and Rictor (show RICTOR Antibodies). This represses GSK-3beta (show GSK3b Antibodies) activity and prevents/reverses cardiac hypertrophy.

  9. role of STIM1, Orai1 (show TMEM132A Antibodies) and TRPCs, and thus SOCE, in thrombus formation, suggests that therapies directed against SOCE and targeting these molecules during cardiovascular and cerebrovascular events could improve traditional anti-thrombotic treatments

  10. Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis

STIM1 Antigen Profile

Antigen Summary

This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene.

Alternative names and synonyms associated with STIM1

  • stromal interaction molecule 1 (STIM1) antibody
  • stromal interaction molecule 1 (stim1) antibody
  • stromal interaction molecule 1a (stim1a) antibody
  • stromal interaction molecule 1b (stim1b) antibody
  • stromal interaction molecule 1 (Stim1) antibody
  • stromal interaction molecule 1 (LOC100345564) antibody
  • D11S4896E antibody
  • GOK antibody
  • MGC76045 antibody
  • MGC154748 antibody
  • si:ch211-112l17.2 antibody
  • si:dkey-24p1.5 antibody
  • SIM antibody
  • Stim1 antibody
  • TAM antibody

Protein level used designations for STIM1

stromal interaction molecule 1 , stromal interaction molecule 1b

GENE ID SPECIES
419082 Gallus gallus
100171399 Sus scrofa
100053079 Equus caballus
403095 Xenopus (Silurana) tropicalis
450973 Pan troglodytes
556360 Danio rerio
779419 Xenopus laevis
100005700 Danio rerio
100188967 Bombyx mori
100345564 Oryctolagus cuniculus
100380565 Salmo salar
6786 Homo sapiens
608643 Canis lupus familiaris
534816 Bos taurus
20866 Mus musculus
361618 Rattus norvegicus
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