Browse our anti-DNA2 (DNA2) Antibodies

Full name:
anti-DNA Replication Helicase 2 Homolog (Yeast) Antibodies (DNA2)
On are 25 DNA Replication Helicase 2 Homolog (Yeast) (DNA2) Antibodies from 10 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 31 DNA2 products are currently listed.
dna2-A, Dna2l, E130315B21Rik, hDNA2, PEOA6, XDna2
list all antibodies Gene Name GeneID UniProt
DNA2 327762 Q6ZQJ5
DNA2 1763 P51530
DNA2 309762  

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Most Popular Reactivities for anti-DNA2 (DNA2) Antibodies

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anti-Mouse (Murine) DNA2 Antibodies:

anti-Human DNA2 Antibodies:

anti-Rat (Rattus) DNA2 Antibodies:

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More Antibodies against DNA2 Interaction Partners

Mouse (Murine) DNA Replication Helicase 2 Homolog (Yeast) (DNA2) interaction partners

  1. The authors establish that a second Dna2-Rpa interaction is mutually exclusive with Rpa-DNA interactions and mediates the displacement of Rpa from ssDNA.

  2. DNA2 helicase cleaves G-quadruplex DNA and is required for telomere integrity.DNA2 reduces replication stress at telomeres, thereby preserving genome stability and suppressing cancer development.

  3. Characterization of the endonuclease and ATP-dependent flap (show ALOX5AP Antibodies) endo/exonuclease (show EXO1 Antibodies) of Dna2.

Human DNA Replication Helicase 2 Homolog (Yeast) (DNA2) interaction partners

  1. the motor of DNA2 functions as a ssDNA translocase to promote degradation of 5'-terminated DNA.

  2. The suppression of FANCD2 (show FANCD2 Antibodies)(-/-) by DNA2 knockdowns suggests that DNA2 and FANCD2 (show FANCD2 Antibodies) also have antagonistic roles: in the absence of FANCD2 (show FANCD2 Antibodies), DNA2 somehow corrupts repair.

  3. BRCA1 and CtIP (show RBBP8 Antibodies) contribute to DSB resection by recruiting Dna2 to damage sites, thus ensuring the robust DSB resection necessary for efficient homologous recombination.

  4. depletion of DNA2 in cells reduces proliferation, addition of estrogen restores proliferation. cells responding to estrogen will proliferate despite impaired in DNA2 activity, potentially promoting genomic instability and triggering cancer development.

  5. EXO1 (show EXO1 Antibodies), MRE11 (show MRE11A Antibodies), and CtIP (show RBBP8 Antibodies) are not involved in the same mechanism of reversed fork processing, whereas human RECQ1 (show RECQL Antibodies) limits DNA2 activity by preventing extensive nascent strand degradation.

  6. DNA2 stimulates the helicase activity of BLM.

  7. WRN (show RECQL2 Antibodies) and BLM act epistatically with DNA2 to promote the long-range resection of double strand break ends in human cells.

  8. DNA2 interacts with FANCD2 (show FANCD2 Antibodies), and cisplatin induces FANCD2 (show FANCD2 Antibodies) ubiquitylation even in the absence of DNA2.

  9. These results implicate human DNA2 and the long-patch base-excision repair pathway in the pathogenesis of adult-onset disorders of mtDNA maintenance.

  10. A characterization of the substrate specificities influencing hDna2 binding and cleavage functions and the sequential interaction of hFEN1 and hDna2 on Okazaki fragment intermediates.

Xenopus laevis DNA Replication Helicase 2 Homolog (Yeast) (DNA2) interaction partners

  1. Dna2 co-localizes in foci with RPA (show RPA1 Antibodies) and is found in a complex with replication fork components And-1 and Mcm10 (show MCM10 Antibodies). Dna2 interacts with the DSB repair and checkpoint proteins Nbs1 (show NLRP2 Antibodies) and ATM (show ATM Antibodies).

  2. Results provide strong evidence that xDNA2 is a major nuclease (show DCLRE1C Antibodies) for the resection of DNA ends for homology-dependent DNA double-strand break repair in eukaryotes.

DNA2 Antigen Profile

Antigen Summary

DNA2 is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability (Duxin et al., 2009

Alternative names and synonyms associated with DNA2

  • DNA replication helicase 2 homolog (yeast) (DNA2) antibody
  • DNA replication helicase 2 homolog (yeast) (Dna2) antibody
  • DNA replication helicase/nuclease 2 (DNA2) antibody
  • DNA replication helicase/nuclease 2 (Dna2) antibody
  • DNA replication helicase/nuclease 2 (dna2) antibody
  • dna2-A antibody
  • Dna2l antibody
  • E130315B21Rik antibody
  • hDNA2 antibody
  • PEOA6 antibody
  • XDna2 antibody

Protein level used designations for DNA2

DNA replication ATP-dependent helicase-like homolog , DNA replication ATP-dependent helicase/nuclease DNA2 , DNA2-like helicase , DNA replication helicase 2 homolog , helicase

489015 Canis lupus familiaris
327762 Mus musculus
423688 Gallus gallus
1763 Homo sapiens
309762 Rattus norvegicus
378492 Xenopus laevis
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