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Human Monoclonal RUVBL1 Primary Antibody for IF, PLA - ABIN563710
Kaji, Fertig, Medsger, Satoh, Hoshino, Hamaguchi, Hasegawa, Lucas, Schnure, Ogawa, Sato, Takehara, Fujimoto, Kuwana: Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement. in Arthritis care & research 2014
Human Polyclonal RUVBL1 Primary Antibody for ICC, IF - ABIN4351482
Tyleckova, Hrabakova, Mairychova, Halada, Radova, Dzubak, Hajduch, Gadher, Kovarova: Cancer cell response to anthracyclines effects: mysteries of the hidden proteins associated with these drugs. in International journal of molecular sciences 2013
xPontin and xReptin (show RUVBL2 Antibodies) are essential genes regulating cell proliferation in early Xenopus embryogenesis through interaction with c-Myc (show MYC Antibodies)
Pontin has a mitosis-specific function in regulating microtubule assembly
the reptin (show RUVBL2 Antibodies)/pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin (show CTNNB1 Antibodies) pathway
The interaction between RUVBL1 and ITFG1 (show ITFG1 Antibodies) is required for breast cancer cell collective invasion and progression.
Methylation of RUVBL1 by the arginine methyltransferase PRMT5 (show PRMT5 Antibodies) is required for homologous recombination-mediated double-strand break repair by promoting TIP60 (show KAT5 Antibodies)-mediated histone H4K16 acetylation.
association of c-FLIPL (show CFLAR Antibodies) and TIP49 provided an additional mechanism involved in c-FLIPL (show CFLAR Antibodies)-mediated functions, including Wnt (show WNT2 Antibodies) activation
Adenovirus E1A (show BCKDHA Antibodies) was found to bind to RuvBL1 via the C terminus of E1A (show BCKDHA Antibodies), and this interaction was important for suppression of interferon (show IFNA Antibodies)-stimulated gene transcriptional activation and recruitment of E1A (show BCKDHA Antibodies) to interferon (show IFNA Antibodies)-regulated promoters.
The interaction of ECD with RUVBL1, and its CK2-mediated phosphorylation, independent of its interaction with PIH1D1, are important for its cell cycle regulatory function.
Results highlight an important role and mechanism for Pontin, a new mutp53 partner, in promoting mutp53 GOF in tumorigenesis.
data thus demonstrate that RUVBL1 is essential for efficient mitosis and proliferation.
by means of molecular docking approaches we first modeled the structures of hetero-hexameric TIP49 ( TIP49a and TIP49b (show RUVBL2 Antibodies) )complexes with short ds-DNA fragments (20 base pairs with different GC content) within the central channel of hexameric ring
Study showed that pontin is up-regulated in renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) and high cytoplasmic pontin expression was associated with poor survival of RCC (show XRCC1 Antibodies) patients.
RuvbL1 and RuvbL2 (show RUVBL2 Antibodies) enhance aggresome formation and disaggregate amyloid fibrils.
accumulating E2f1 (show E2F1 Antibodies) progressively recruits a Pontin/Reptin (show RUVBL2 Antibodies) complex to open the chromatin conformation at E2f (show E2F1 Antibodies) target genes and amplifies the E2f (show E2F1 Antibodies) transcriptional response.
Pontin functions as an essential coactivator for Oct4 (show POU5F1 Antibodies)-dependent large intergenic noncoding RNA expression in mouse embryonic stem cells.
Loss of Ruvbl1 gene is associated with bone marrow failure.
nuclear DNA helicase that binds TBP; involved in recombination and transcription
, RuvB-like 1 (E. coli)
, RuvB-like 1-like
, ruvB-like 1-like
, RuvB-like 1
, 49 kDa TATA box-binding protein-interacting protein
, 49 kDa TBP-interacting protein
, 54 kDa erythrocyte cytosolic protein
, INO80 complex subunit H
, NMP 238
, RuvB (E coli homolog)-like 1
, TATA binding protein interacting protein 49 kDa
, TIP60-associated protein 54-alpha
, nuclear matrix protein 238
, pontin 52
, DNA helicase p50
, RuvB-like protein 1
, Pontin 52