Browse our TANK-Binding Kinase 1 (TBK1) ELISA Kits

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TANK-Binding Kinase 1 ELISA Kits (TBK1)
On are 15 TANK-Binding Kinase 1 (TBK1) ELISA Kits from 9 different suppliers available. Additionally we are shipping TANK-Binding Kinase 1 Antibodies (156) and TANK-Binding Kinase 1 Proteins (11) and many more products for this protein. A total of 192 TANK-Binding Kinase 1 products are currently listed.
1200008B05Rik, AI462036, AW048562, NAK, T2K, TBK1, wu:fk70c05, zgc:136548
list all ELISA KIts Gene Name GeneID UniProt
TBK1 29110 Q9UHD2
TBK1 56480 Q9WUN2
TBK1 299827  

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More ELISA Kits for TANK-Binding Kinase 1 Interaction Partners

Zebrafish TANK-Binding Kinase 1 (TBK1) interaction partners

  1. Fish IRF6 (show IRF6 ELISA Kits) is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 (show MYD88 ELISA Kits) and TBK1, suggesting that differences in the IRF6 (show IRF6 ELISA Kits) regulation pattern exist between lower and higher vertebrates.

Human TANK-Binding Kinase 1 (TBK1) interaction partners

  1. Mutations in the TANK-binding kinase 1 (TBK1) gene were identified as a cause for amyotrophic lateral sclerosis (ALS (show IGFALS ELISA Kits)) with or without comorbid frontotemporal dementia.

  2. The occurrence of TBK1 mutations in FTD (show FTL ELISA Kits) and ALS (show IGFALS ELISA Kits) underlines the fact that FTD (show FTL ELISA Kits) and ALS (show IGFALS ELISA Kits) are part of the same disease spectrum. For future therapeutic trials, characterization of TBK1 mutation carriers in presymptomatic cohorts, such as the genetic frontotemporal dementia initiative (GENFI), is of great importance.

  3. demonstrate a key role of TBK1/IKKepsilon (show IKBKE ELISA Kits) in the survival and proliferation of HTLV-1-transformed T cells

  4. Data suggest that Encephalomyocarditis virus 3C protease cleaves TANK and disrupts the TANK-TBK1-IKKepsilon (show IKBKE ELISA Kits)-IRF3 (show IRF3 ELISA Kits) complex, resulting in reduction in IRF3 (show IRF3 ELISA Kits) phosphorylation and type I interferon (show IFNA ELISA Kits) production. (TANK = TRAF family member associated NFKB activator (show TANK ELISA Kits); TBK1 = TANK binding kinase 1; IKKepsilon (show IKBKE ELISA Kits) = inhibitor of nuclear factor kappa B kinase subunit epsilon (show IKBKE ELISA Kits); IRF3 (show IRF3 ELISA Kits) = interferon regulatory factor 3 (show IRF3 ELISA Kits))

  5. Data suggest that changes in inhibitor of nuclear factor kappa B kinase subunit epsilon (IKKepsilon (show IKBKE ELISA Kits)) and TANK-binding kinase 1 (TBK1) expression may be involved in the development of intestinal-type gastric cancer.

  6. Here the authors show that recruitment of WIPI2 (show WIPI2 ELISA Kits), itself essential for anti-bacterial autophagy, is dependent on the localization of catalytically active TBK1 to the vicinity of cytosolic bacteria.

  7. review of the role of TBK1 in the seemingly unrelated, yet allelic diseases amyotrophic lateral sclerosis (ALS (show IGFALS ELISA Kits)), frontotemporal dementia (FTD (show FTL ELISA Kits)), normal tension glaucoma (NTG (show OPA1 ELISA Kits)) and childhood herpes simplex encephalitis and discuss the role of TBK1 in neuroinflammatory diseases

  8. Enrichment of qualifying variants toward glaucoma was present in all genes except WDR36, in which controls harbored more variants, and TBK1, in which no qualifying variants were detected in cases or controls.

  9. Human herpesvirus 1 ICP27 interacted with TBK1 and STING in a manner that was dependent on TBK1 activity and the RGG motif in ICP27 and inhibited type I IFN induction through the cGAS-STING-TBK1 pathway in human macrophages.

  10. Upon cytosolic DNA stimulation, STAT3 (show STAT3 ELISA Kits) Ser (show SIGLEC1 ELISA Kits)(754) is directly phosphorylated by TBK1 in a STING-dependent manner. Moreover, Ser (show SIGLEC1 ELISA Kits)(754) phosphorylation inhibits cytosolic DNA-induced STAT3 (show STAT3 ELISA Kits) transcriptional activity and selectively reduces STAT3 (show STAT3 ELISA Kits) target genes that are up-regulated in response to cytosolic DNA

Mouse (Murine) TANK-Binding Kinase 1 (TBK1) interaction partners

  1. USP38 inhibits type I interferon signaling by editing TBK1 ubiquitination through NLRP4 signalosome.

  2. The authors report that Raf kinase inhibitory protein (RKIP (show PEBP1 ELISA Kits)) is essential for TBK1 activation and type I interferon (show IFNA ELISA Kits) production triggered by viral infection.

  3. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 (show FOSL1 ELISA Kits) "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (show TRAF3 ELISA Kits)), TIR domain-containing adapter inducing IFN-beta (show IFNB1 ELISA Kits) (TRIF (show RNF138 ELISA Kits)), and Tank-binding kinase 1 (TBK1) via impairing K63-linked polyubiquitination of TRAF3 (show TRAF3 ELISA Kits) and TRIF (show RNF138 ELISA Kits).

  4. TBK1 complexes required for the phosphorylation of IRF3 (show IRF3 ELISA Kits) and the production of interferon-beta (show IFNB1 ELISA Kits) have been identified.

  5. this study reveals a previously unknown ICOS (show ICOS ELISA Kits)-TBK1 signaling pathway that specifies the commitment of germinal center follicular helper T cells

  6. Innate immune responses to adenovirus vectors are largely TBK1-dependent in the spleen but TBK1-independent in the liver

  7. Data show that the formation of a tripartite ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 ELISA Kits))-STING membrane protein-TANK-binding kinase 1 (TBK1) complex was necessary for the activation of interferon regulatory factor-3 (IRF3 (show IRF3 ELISA Kits)).

  8. This study suggest that TBK1 exerts pronociceptive effects in inflammatory nociception which are due to both modulation of NF-kappaB dependent genes and regulation of MAPKs and c-fos.

  9. TRIM27 (show RFP ELISA Kits) inhibits VSV infection-induced type I IFN production by promoting TBK1 degradation.

  10. Suggest that by reducing production of cAMP in adipocytes, PDE3B, IKKepsilon (show IKBKE ELISA Kits) and TBK1 may contribute to the repression of energy expenditure during obesity.

TANK-Binding Kinase 1 (TBK1) Antigen Profile

Antigen Summary

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Alternative names and synonyms associated with TANK-Binding Kinase 1 (TBK1)

  • TANK-binding kinase 1 (tbk1) Elisa Kit
  • TANK-binding kinase 1 (TBK1) Elisa Kit
  • TANK-binding kinase 1 (LOC100358771) Elisa Kit
  • TANK-binding kinase 1 (Tbk1) Elisa Kit
  • 1200008B05Rik Elisa Kit
  • AI462036 Elisa Kit
  • AW048562 Elisa Kit
  • NAK Elisa Kit
  • T2K Elisa Kit
  • TBK1 Elisa Kit
  • wu:fk70c05 Elisa Kit
  • zgc:136548 Elisa Kit

Protein level used designations for TANK-Binding Kinase 1 (TBK1) ELISA Kits

serine/threonine-protein kinase TBK1 , TANK-binding kinase 1 , NF-kappa-B-activating kinase , TANK binding kinase 1 , serine/threonine protein kinase TBK1 , serine/threonine-protein kinase TBK1-like , NF-kB-activating kinase , T2K

446351 Xenopus laevis
452047 Pan troglodytes
692289 Danio rerio
717427 Macaca mulatta
100051650 Equus caballus
100125828 Sus scrofa
100216212 Xenopus (Silurana) tropicalis
100358771 Oryctolagus cuniculus
100399701 Callithrix jacchus
100433568 Pongo abelii
100484104 Ailuropoda melanoleuca
100553575 Anolis carolinensis
100582856 Nomascus leucogenys
29110 Homo sapiens
481145 Canis lupus familiaris
533141 Bos taurus
56480 Mus musculus
299827 Rattus norvegicus
417825 Gallus gallus
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