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Mouse (Murine) SAA1 ELISA Kit for Sandwich ELISA - ABIN822171
Kleiner, Celsi, Tricarico, Zacchigna, Crovella, Marcuzzi: Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: a strain-comparative study. in In vivo (Athens, Greece) 2013
Show all 2 references for ABIN822171
Human SAA1 ELISA Kit for Sandwich ELISA - ABIN414457
Ma, Luo, Wu, Chen, Kou, Wang: Circulation levels of acute phase proteins in patients with Takayasu arteritis. in Journal of vascular surgery 2010
Show all 2 references for ABIN414457
SAA is a potential new uremic toxin involved in uremia-related atherosclerosis through interaction with RAGE (show AGER ELISA Kits).
Data indicate that SAA1 overexpressing mice (TG) show significant deficits in social behaviors, including impaired social recognition and reduced social interaction. Study detected exogenous SAA1 expression in the brain of TG mice, implying that liver-derived SAA1 migrates to the brain. Results show an increase in the accumulation of the 87kDa form of Abeta (show APP ELISA Kits) in TG mice compared to wild type mice.
Mass spectrometry analysis of peptides derived from chemically crosslinked HDL (show HSD11B1 ELISA Kits)-SAA particles detected multiple crosslinks between apoA1 (show APOA1 ELISA Kits) and SAA, indicating close proximity (within 25 A) of these two proteins on the HDL (show HSD11B1 ELISA Kits) surface, providing a molecular and structural mechanism for the simultaneous binding of heparin to apoA1 (show APOA1 ELISA Kits) and SAA.
The findings identify SR-BII (show SCARB2 ELISA Kits) as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK (show MAPK1 ELISA Kits)-mediated signaling pathways.
Sustained, elevated levels of SAA1 were correlated with metabolic parameters and local cytokine expression in the liver following 16 weeks on the high-fat diet. We suggest that SAA1-derived amyloid deposition under long-term high-fat diet exposure may be associated with the complications of high-fat diet-induced obesity and metabolic disorders.
SAA inhibits osteoclast formation from mouse macrophages. SAA blocks RANKL (show TNFSF11 ELISA Kits)-induced osteoclastogenesis.
Serum Amyloid A induces inflammation, proliferation and cell death in activated hepatic stellate cells.
These data demonstrate that SAA stimulates a robust pro-inflammatory response in skeletal muscle myotubes via the TLR2 (show TLR2 ELISA Kits)-dependent release of IL-6 (show IL6 ELISA Kits) and TNFalpha (show TNF ELISA Kits).
Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL (show HSD11B1 ELISA Kits)
SAA1/2 produced by macrophages promotes early lesion formation in the ascending aorta in LDLR (show LDLR ELISA Kits) knockout mice.
The SAA1.1 allele was found in four familial Mediterranean fever (show MEFV ELISA Kits) patients, including two with AA amyloidosis.
genetic variants at the CRP (show CRP ELISA Kits) and SAA1 loci independently affect both CRP (show CRP ELISA Kits) and SAA levels, and their respective circulating levels act as suppressors.
Serum amyloid A could represent a novel marker of primary unexplained recurrent early pregnancy loss because affected women exhibited elevated levels of this protein.
The polymorphism of SAA1 is not associated with susceptibility and severity of Familial Mediterranean Fever (show MEFV ELISA Kits) in Egyptian children
Correlate MEFV (show MEFV ELISA Kits) genotype and the SAA1 polymorphisms with the clinical manifestations of familial Mediterranean fever (show MEFV ELISA Kits) and the occurrence of amyloidosis in a large cohort of Armenian patients.
Study found increased SAA concentration in patients with sarcoidosis.
the detection of residues 76 and 77 of SAA (AA76) may alter the ability to diagnose AA amyloidosis.
The results demonstrated that SAA upregulated Visfatin (show NAMPT ELISA Kits) expression in cultured RAW264.7 macrophages and in the primary monocytes.
Structure, function and SAA1 gene polymorphisms
polymorphisms in the SAA2 gene are associated with milk production traits in Chinese Holstein cows
endometritis gives rise to a systemic acute phase response and an up-regulated endometrial gene expression of SAA and several pro-and anti-inflammatory cytokines
The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
serum amyloid A protein
, serum amyloid A1
, serum amyloid a protein
, serum amyloid A 2
, serum amyloid A-1 protein
, serum amyloid A
, serum amyloid A-3 protein
, tumor protein p53 inducible protein 4
, serum amyloid A2