Browse our SRSF Protein Kinase 1 Proteins (SRPK1)

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SRSF Protein Kinase 1 Proteins (SRPK1)
On are 7 SRSF Protein Kinase 1 (SRPK1) Proteins from 5 different suppliers available. Additionally we are shipping SRSF Protein Kinase 1 Antibodies (121) and SRSF Protein Kinase 1 Kits (2) and many more products for this protein. A total of 140 SRSF Protein Kinase 1 products are currently listed.
atc, AU017960, BEST:CK01209, CG9085, CG11489, CK01209, Dmel\\CG11489, SFRSK1, SRPK, srpk1, Srpk79D, wu:fc06h03, zgc:63789
list all proteins Gene Name GeneID UniProt
SRPK1 20815 O70551
SRPK1 6732 Q96SB4
Rat SRPK1 SRPK1 361811  

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SRSF Protein Kinase 1 Proteins (SRPK1) by Origin

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Top referenced SRSF Protein Kinase 1 Proteins

  1. Human SRPK1 Protein expressed in Baculovirus infected Insect Cells - ABIN2005139 : Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: Lysine acetylation targets protein complexes and co-regulates major cellular functions. in Science (New York, N.Y.) 2009 (PubMed)
    Show all 2 references for 2005139

More Proteins for SRSF Protein Kinase 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. Mutation of the Srpk79D gene causes conspicuous accumulations of BRP (show GDF5 Proteins) in larval and adult nerves.

  2. SRPK79D is a novel T-bar-associated protein kinase (show CDK7 Proteins) that represses T-bar assembly in peripheral axons, and that SRPK79D-dependent repression must be relieved to facilitate site-specific AZ assembly.

Mouse (Murine) SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. In 2 independent murine models of breast tumor metastasis, stable shRNA-based SRPK1 knockdown suppressed metastasis to distant organs, including lung, liver, and spleen, and inhibited focal adhesion reorganization.

  2. SRPK1 overexpression is also tumorigenic because excess SRPK1 squelches PHLPP1.

  3. SRPK1 expression might be an important prognostic indicator for the chemoresponsiveness of nonseminomatous male germ cell tumors.

Human SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. SRPK1 interacts with an RS-like domain in the N terminus of CLK1 (show CDK11B Proteins) to facilitate the release of phosphorylated SR proteins, which then promotes efficient splice-site recognition and subsequent spliceosome assembly.

  2. Data indicate that proto-oncogene (show RAB1A Proteins) protein c-akt (Akt (show AKT1 Proteins)) phosphorylates distinct sites than SRPK1 protein within the arginine-serine (RS) domain of Lamin B Receptor (LBR (show LBR Proteins)).

  3. SRPK1 interference inhibits the growth and invasion of RCC (show XRCC1 Proteins) cells.

  4. SRPK1 is overexpressed in HCC (show FAM126A Proteins) and may be a promising indicator of prognosis for HCC (show FAM126A Proteins) patients

  5. Overexpression of SRPK1 is associated with glioma.

  6. The mRNA level and the protein level of SRPK1 were up-regulated in NSCLC tissues. It activated the transcriptional activity of beta-catenin/T-cell factor complex. SRPK1 knockdown attenuated the expression of target genes of this complex. Silencing SRPK1 down-regulated the phosphorylation of GSK3beta.

  7. SRPK1 is upregulated in prostate cancer and correlates with disease stage and invasion.

  8. Data indicate serine/arginine-rich protein (show MANF Proteins) kinases SRPK1/2/SRPIN340 complexes by molecular docking and molecular dynamics.

  9. SRPK1 mediates TGF-beta (show TGFB1 Proteins)-induced proliferation.

  10. SRPK1 may be a potential anticancer target to inhibit glioma progression.

SRSF Protein Kinase 1 (SRPK1) Protein Profile

Protein Summary

This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.

Alternative names and synonyms associated with SRSF Protein Kinase 1 (SRPK1)

  • SRSF protein kinase 1 (SRPK1)
  • serine-arginine protein kinase at 79D (srpk79D)
  • serine/arginine-rich protein specific kinase 1a (srpk1a)
  • serine/arginine-rich protein specific kinase 1 (Srpk1)
  • SRSF protein kinase 1 (Srpk1)
  • atc protein
  • AU017960 protein
  • BEST:CK01209 protein
  • CG9085 protein
  • CG11489 protein
  • CK01209 protein
  • Dmel\\CG11489 protein
  • SFRSK1 protein
  • SRPK protein
  • srpk1 protein
  • Srpk79D protein
  • wu:fc06h03 protein
  • zgc:63789 protein

Protein level used designations for SRSF Protein Kinase 1 Proteins (SRPK1)

CG11489-PB , CG11489-PE , CG11489-PF , CG11489-PH , CG11489-PI , CG11489-PJ , CG11489-PK , CG11489-PL , CG11489-PM , CG11489-PN , CG11489-PO , air traffic controller , srpk79D-PB , srpk79D-PE , srpk79D-PF , srpk79D-PH , srpk79D-PI , srpk79D-PJ , srpk79D-PK , srpk79D-PL , srpk79D-PM , srpk79D-PN , srpk79D-PO , serine/arginine-rich protein specific kinase 1 , SRSF protein kinase 1 , SFRS protein kinase 1 , SR protein-specific kinase 1 , SR-protein-specific kinase 1 , serine/arginine-rich protein-specific kinase 1 , serine/threonine-protein kinase SRPK1 , serine/arginine-rich splicing factor kinase 1 , Serine/threonine-protein kinase SRPK1

100063400 Equus caballus
40461 Drosophila melanogaster
323679 Danio rerio
100593994 Nomascus leucogenys
20815 Mus musculus
6732 Homo sapiens
361811 Rattus norvegicus
474887 Canis lupus familiaris
100155422 Sus scrofa
512631 Bos taurus
100172042 Pongo abelii
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