Browse our anti-ATP7B (ATP7B) Antibodies

Full name:
anti-ATPase, Cu++ Transporting, beta Polypeptide Antibodies (ATP7B)
On www.antibodies-online.com are 158 ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) Antibodies from 24 different suppliers available. Additionally we are shipping ATP7B Proteins (11) and ATP7B Kits (8) and many more products for this protein. A total of 182 ATP7B products are currently listed.
Synonyms:
Atp7a, ATP7B, Hts, PINA, PWD, tx, WC1, Wd, WND
list all antibodies Gene Name GeneID UniProt
ATP7B 540 P35670
ATP7B 11979 Q64446
ATP7B 24218  

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anti-Human ATP7B Antibodies:

anti-Mouse (Murine) ATP7B Antibodies:

anti-Rat (Rattus) ATP7B Antibodies:

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Top referenced anti-ATP7B Antibodies

  1. Human Polyclonal ATP7B Primary Antibody for ICC, IF - ABIN151824 : Safaei, Otani, Larson, Rasmussen, Howell: Transport of cisplatin by the copper efflux transporter ATP7B. in Molecular pharmacology 2008 (PubMed)
    Show all 8 references for 151824

  2. Human Monoclonal ATP7B Primary Antibody for ELISA, WB - ABIN393414 : Singleton, McInnes, Cater, Winnall, McKirdy, Yu, Taylor, Ke, Richardson, Mercer, La Fontaine: Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 393414

  3. Human Polyclonal ATP7B Primary Antibody for ICC, IF - ABIN151825 : Guo, Nyasae, Braiterman, Hubbard: NH2-terminal signals in ATP7B Cu-ATPase mediate its Cu-dependent anterograde traffic in polarized hepatic cells. in American journal of physiology. Gastrointestinal and liver physiology 2005 (PubMed)
    Show all 2 references for 151825

  4. Human Polyclonal ATP7B Primary Antibody for IHC (p), WB - ABIN3042569 : Wu, Yi, Sui, Jiang, Jiang, Zhao: Expression of ATP7B in human gastric cardiac carcinomas in comparison with distal gastric carcinomas. in World journal of gastroenterology 2006 (PubMed)
    Show all 2 references for 3042569

  5. Human Polyclonal ATP7B Primary Antibody for IF (p), IHC (p) - ABIN733433 : Wang, Zhu, Zhao, Wang: miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression. in International journal of molecular medicine 2016 (PubMed)

  6. Human Monoclonal ATP7B Primary Antibody for ELISA, WB - ABIN560009 : Ansede, Wright, St Claire, Hart, Gefroh, Brouwer: Characterization of sandwich-cultured hepatocytes as an in vitro model to assess the hepatobiliary disposition of copper. in Drug metabolism and disposition: the biological fate of chemicals 2009 (PubMed)

  7. Human Polyclonal ATP7B Primary Antibody for IF, IHC - ABIN1533712 : Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: The DNA sequence and analysis of human chromosome 13. ... in Nature 2004 (PubMed)

More Antibodies against ATP7B Interaction Partners

Cow (Bovine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. Data show that CD4 (show CD4 Antibodies)(+) and WC1(+) gammadelta T-cells were induced to produce IL-17 (show IL17A Antibodies) termed Th17 and gammadelta17 cells.

  2. The endocytosis and signaling of the gamma-delta T cell coreceptor WC1 are regulated by a dileucine motif.

  3. WC1 is a hybrid gamma-delta TCR coreceptor and pattern recognition receptor for pathogenic bacteria.

  4. Identification of differences in the signal transduction through the endodomains of WC1 contributes to understanding the functional role of the WC1 coreceptors in the gammadelta T cell responses.

  5. Specific receptors in the WC1 family directly participate in Leptospira recognition and/or activation of gamma-delta T cells.

  6. These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(high) T cell population, which showed Foxp3 (show FOXP3 Antibodies) transcription/expression, natural regulatory activity did not reside in this cell population

  7. Sudies demonstrate that WC1 molecules are encoded by a large, multi-gene family whose transcripts undergo extensive alternative splicing.

Human ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. The P-type copper ATPases ATP7A (show ATP7A Antibodies) and ATP7B provide an important system for acquisition, active transport, distribution and elimination of copper. Relevance of copper metabolism to human diseases and therapy is already known. It is quite certain that further studies will reveal detailed and useful information on biochemical mechanisms and relevance to diseases

  2. the mechanism of copper-dependent regulation of ATP7B and ATP7A (show ATP7A Antibodies), the roles of individual MBDs, and the relationship between the regulatory and catalytic copper binding are still unknown. We describe the structure and dynamics of the MBDs, review the current knowledge about their functional roles and propose a mechanism of regulation of ATP7B by copper-dependent changes in the dynamics and conformation of the MBD (show DPEP1 Antibodies) chain.

  3. ATP-dependent copper transfer in ATP7A (show ATP7A Antibodies)/B is not affected by varying the pH, suggesting that net proton counter-transport may not occur in copper ATPases. Platinum anticancer drugs activate ATP7A (show ATP7A Antibodies)/B and are subjected to ATP-dependent vectorial displacement with a mechanism analogous to that of copper

  4. Expression of the most frequent ATP7B mutant, H1069Q, activates p38 (show CRK Antibodies) and c-Jun N-terminal kinase signaling pathways, which favor the rapid degradation of the mutant.

  5. Results reveal that partial gene deletions in ATP7B represent causative mutations in some of the uncharacterized Wilson's disease alleles.

  6. It has been demonstrated in ovarian cancer cells that cisplatin resistance and uptake correlates with reduced CTR1 (show SLC31A1 Antibodies) and LRRC8A (show LRRC8A Antibodies) protein expression/activity and a concomitant upregulation in cisplatin exporting transporters (ATP7A (show ATP7A Antibodies), ATP7B), which implies that the resistant cells have a reduced ability to accumulate cisplatin and activate proapoptotic transporters for osmolytes.

  7. Stratified analysis by genotypes revealed that both outdoor and indoor copper exposure increased inattentiveness in ATP7B rs1061472-CC and rs1801243-CC carriers.

  8. ATP7B mutant cell lines showed different degrees of cell survival and characteristic responses upon treatment with Zn and D-penicillamine.

  9. Five of the nineteen mutations in ATP7B were newly detected mutations; moreover, 8 of these mutations were polymorphic (2 were newly identified).

  10. miR (show MLXIP Antibodies)-133a enhances the sensitivity of multidrug-resistant epithelial cells to cisplatin by downregulating ATP7B expression.

Mouse (Murine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. This study showed that knockout of Atp7b led to altered lipid metabolism and liver steatosis in the absence of inflammation.

  2. ATP7B is transported from the trans-Golgi network (TGN (show TG Antibodies)) to the bile canaliculus by basolateral sorting and endocytosis, and microtubule-mediated transcytosis through the subapical compartment.

  3. Data indicate that the copper-transporting ATPase (show DNAH8 Antibodies) gene (Atp7b) knockout mice showed a drastic, time-dependent accumulation of hepatic copper.

  4. The aim of this study was to identify copper disturbances according to various brain compartments and further dissect the causal relationship between copper storage and neuronal damage using Atp7b(-/-) mice.

  5. DKWSLLL sequence is essential for ATP7b sorting at the TGN (show TG Antibodies), transport from the TGN (show TG Antibodies) to the PM, endocytosis, and recycling to the TGN (show TG Antibodies) and PM.

  6. Ligand-activated nuclear receptors FXR/NR1H4 (show NR1H4 Antibodies) and GR/NR3C1 (show NR3C1 Antibodies) and nuclear receptor interacting partners are less abundant in Atp7b(-/-) hepatocyte nuclei.

  7. By performing dynamic PET, authors obtained the first real-time measurements of 64Cu distribution in the organs or tissues of Atp7b -/- mice.

  8. Clusterin (show CLU Antibodies) and COMMD1 (show COMMD1 Antibodies) independently regulate degradation of the mammalian copper ATPases ATP7A (show ATP7A Antibodies) and ATP7B.

  9. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease.

  10. The Jackson toxic milk mouse as a model for copper loading

Pig (Porcine) ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) interaction partners

  1. A copper-dependent ATPase (show DNAH8 Antibodies) hydrolysis in a native Golgi-enriched preparation from liver, was characterized.

ATP7B Antigen Profile

Antigen Summary

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD).

Alternative names and synonyms associated with ATP7B

  • ATPase, Cu++ transporting, beta polypeptide (ATP7B) antibody
  • ATPase, Cu++ transporting, beta polypeptide (atp7b) antibody
  • ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (atp7b) antibody
  • ATPase, Cu++ transporting, beta polypeptide (LOC100344865) antibody
  • ATPase, Cu++ transporting, beta polypeptide (Atp7b) antibody
  • BoWC1.1 (WC1) antibody
  • CD163 molecule-like 1 (CD163L1) antibody
  • Atp7a antibody
  • ATP7B antibody
  • Hts antibody
  • PINA antibody
  • PWD antibody
  • tx antibody
  • WC1 antibody
  • Wd antibody
  • WND antibody

Protein level used designations for ATP7B

ATPase, Cu++ transporting, beta polypeptide , copper-transporting ATPase beta subunit , ATPase, Cu++ transporting, beta polypeptide (Wilson disease) , Wilson's disease protein , copper-transporting ATPase , copper-transporting ATPase 2 , ATP7B-like , copper-transporting ATPase 2-like , ATPase, Cu(2+)- transporting, beta polypeptide , Wilson disease-associated protein , copper pump 2 , Wilson protein , toxic milk , wilson disease-associated protein homolog , ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease) , PINA gene, promoter , pineal night-specific ATPase , ATPase, Cu(2+)-transporting, beta polypeptide , ATPase 7B protein , scavenger receptor cysteine-rich type 1 protein M160 , scavenger-receptor protein

GENE ID SPECIES
518075 Bos taurus
442967 Canis lupus familiaris
476903 Canis lupus familiaris
556499 Danio rerio
571325 Danio rerio
592143 Strongylocentrotus purpuratus
713781 Macaca mulatta
100344865 Oryctolagus cuniculus
100469748 Ailuropoda melanoleuca
100497797 Xenopus (Silurana) tropicalis
100028163 Monodelphis domestica
100082671 Ornithorhynchus anatinus
100052751 Equus caballus
100541545 Meleagris gallopavo
100558446 Anolis carolinensis
540 Homo sapiens
11979 Mus musculus
24218 Rattus norvegicus
418879 Gallus gallus
100049684 Sus scrofa
443046 Ovis aries
783109 Bos taurus
100144477 Sus scrofa
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