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Browse our GDF2 Proteins (GDF2)

Full name:
Growth Differentiation Factor 2 Proteins (GDF2)
On are 21 Growth Differentiation Factor 2 (GDF2) Proteins from 10 different suppliers available. Additionally we are shipping GDF2 Antibodies (82) and GDF2 Kits (63) and many more products for this protein. A total of 171 GDF2 products are currently listed.
BMP-9, Bmp9, DSL1
list all proteins Gene Name GeneID UniProt
GDF2 2658 Q9UK05
GDF2 12165 Q9WV56
Rat GDF2 GDF2 290921  

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GDF2 Proteins (GDF2) by Origin

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Top referenced GDF2 Proteins

  1. Mouse (Murine) GDF2 Protein expressed in CHO Cells - ABIN2666778 : Bidart, Ricard, Levet, Samson, Mallet, David, Subileau, Tillet, Feige, Bailly: BMP9 is produced by hepatocytes and circulates mainly in an active mature form complexed to its prodomain. in Cellular and molecular life sciences : CMLS 2012 (PubMed)
    Show all 8 references for ABIN2666778

  2. Human GDF2 Protein expressed in CHO Cells - ABIN2666776 : Herrera, Dooley, Breitkopf-Heinlein: Potential roles of bone morphogenetic protein (BMP)-9 in human liver diseases. in International journal of molecular sciences 2014 (PubMed)
    Show all 8 references for ABIN2666776

More Proteins for GDF2 Interaction Partners

Human Growth Differentiation Factor 2 (GDF2) interaction partners

  1. BMP9 inhibited the proliferation and migration of the A549 cells.

  2. his study shows that BMP9 inhibition is associated with Osteosarcoma (OS) development and that enhanced expression of BMP9 may be a potential treatment method for OS

  3. IGF1 (show IGF1 Proteins) can enhance BMP9-induced osteogenic differentiation in mesenchymal stem cells.

  4. In ovarian and breast epithelial cells, epigenetic regulation of GDF2 suppresses anoikis.

  5. BMP9 also influenced the expression of PPARgamma (show PPARG Proteins).

  6. Data suggest ALK1 (show ACVRL1 Proteins) and ACVR2A (show ACVR2A Proteins)/ACVR2B (show ACVR2B Proteins), acting as BMP9 co-receptors, rearrange pro-domains of BMP9--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  7. DLL4 (show DLL4 Proteins)/Notch1 (show NOTCH1 Proteins) and BMP9 interdependent signaling induces endothelial cell quiescence via P27KIP1 (show CDKN1B Proteins)/thrombospondin pathway.

  8. BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine (show CCL1 Proteins) Responses

  9. BMP-9 induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1 (show ACVRL1 Proteins), Smad (show SMAD1 Proteins) and ALP (show ALP Proteins) dependent mechanisms.

  10. This review summarizes the indirect connection between BMP9 and liver fibrosis, with a focus on the BMP9 signaling pathway members ALK1 (show ACVRL1 Proteins), endoglin (show ENG Proteins), Id1 (show ID1 Proteins), hepcidin (show HAMP Proteins) and Snail (show SNAI1 Proteins). [review]

Mouse (Murine) Growth Differentiation Factor 2 (GDF2) interaction partners

  1. Western blot analysis demonstrated that following BMP2 (show BMP2 Proteins) and BMP7 (show BMP7 Proteins) cotransfection of MC3T3E1 cells, the protein expression levels of BMP2 (show BMP2 Proteins), BMP4 (show BMP4 Proteins), BMP6 (show BMP6 Proteins), BMP7 (show BMP7 Proteins), BMP9 and Wnt3a (show WNT3A Proteins) were increased compared with control cells

  2. he results of the present study demonstrated that BMP9 promoted the osteoclast differentiation of osteoclast precursors via binding to the ALK1 receptor on the cell surface, and inhibiting the ERK1/2 signaling pathways in the cell

  3. that Dkk1 (show DKK1 Proteins) negatively regulates BMP9-induced osteogenic differentiation.

  4. Data show athat beta-catenin (show CTNNB1 Proteins) can be activated by bone morphogenetic protein 9 (BMP9) and the activation of beta-catenin (show CTNNB1 Proteins) plays an important role in the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells induced by BMP9.

  5. miR23b inhibits BMP9induced C2C12 myoblast osteogenesis via targeting of the Runx2 (show RUNX2 Proteins) gene, acting as a suppressor.

  6. We have established a producer line that stably expresses a high level of active BMP9 protein. Such producer line should be a valuable resource for generating biologically active BMP9 protein for studying BMP9 signaling

  7. Data show that microRNA miR (show MLXIP Proteins)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 (show SMAD7 Proteins) protein.

  8. Hh signaling is involved and plays a regulatory role in the osteogenic differentiation of MSCs induced by BMP9.

  9. data indicate that BMP9 and BMP13 (show GDF6 Proteins) (BMP9 might be more effective) promoted the differentiation of C3H10T1/2 cells into cardiomyocyte-like cells

  10. BMP9/ALK1 (show ACVRL1 Proteins) augmented vasculogenesis and angiogenesis, and thereby enhanced neovascularization. Thus, we suggest that BMP9/ALK1 (show ACVRL1 Proteins) may improve the efficacy of EPC (show TCF21 Proteins)-based therapies for treating ischemic diseases.

GDF2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.

Alternative names and synonyms associated with GDF2

  • growth differentiation factor 2 (gdf2)
  • growth differentiation factor 2 (GDF2)
  • growth differentiation factor 2 (Gdf2)
  • BMP-9 protein
  • Bmp9 protein
  • DSL1 protein

Protein level used designations for GDF2

bone morphogenetic protein 9 , GDF-2 , growth/differentiation factor 2 , BMP-9 , DSL-1 , dorsalin-1

563287 Danio rerio
2658 Homo sapiens
12165 Mus musculus
396412 Gallus gallus
540384 Bos taurus
290921 Rattus norvegicus
100351972 Oryctolagus cuniculus
100519741 Sus scrofa
611149 Canis lupus familiaris
101115426 Ovis aries
100723076 Cavia porcellus
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