GDF2 Protein (AA 320-429)
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- Target See all GDF2 Proteins
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 320-429
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Origin
- Human
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Source
- HEK-293 Cells
- Characteristics
- Human GDF-2 Protein, Tag Free
- Purity
- >95 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product GDF2 Protein
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Growth Differentiation Factor 2 (GDF2) (AA 320-429) protein (His-IF2DI Tag)
GDF2 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Growth Differentiation Factor 2 (GDF2) (AA 1-429) protein (GST tag)GDF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 2 (GDF2) (AA 320-419) protein (GST tag)GDF2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Differentiation Factor 2 (GDF2) (AA 320-429) protein (His tag)Crystallography grade GDF2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Growth Differentiation Factor 2 (GDF2) (AA 319-428) protein (His tag)Crystallography grade GDF2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- ACN, TFA in Water
- Storage
- -20 °C
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- Target
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- Alternative Name
- GDF-2 (GDF2 Products)
- Synonyms
- bmp9 Protein, BMP-9 Protein, BMP9 Protein, Bmp9 Protein, DSL1 Protein, growth differentiation factor 2 Protein, gdf2 Protein, GDF2 Protein, Gdf2 Protein
- Background
- Human Growth and differentiation factor 2 (GDF-2), also known as Bone morphogenetic protein 9 (BMP-9), is a member of the BMP subgroup of the TGF-beta superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. GDF-2 Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. ALK1 is a signalling receptor for bone morphogenetic protein-9 (BMP-9) in endothelial cells (ECs). BMP-9 bound with high affinity to ALK1 and endoglin, and weakly to the type-I receptor ALK2 and to the BMP type-II receptor (BMPR-II) and activin type-II receptor (ActR-II) in transfected COS cells. Binding of BMP-9 to ALK2 was greatly facilitated when BMPR-II or ActR-II were co-expressed.
- Molecular Weight
- 12.1 kDa
- Pathways
- Transition Metal Ion Homeostasis
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