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Browse our Heme Oxygenase (Decycling) 1 Proteins (HMOX1)

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Heme Oxygenase (Decycling) 1 Proteins (HMOX1)
On are 46 Heme Oxygenase (Decycling) 1 (HMOX1) Proteins from 13 different suppliers available. Additionally we are shipping Heme Oxygenase (Decycling) 1 Antibodies (361) and Heme Oxygenase (Decycling) 1 Kits (52) and many more products for this protein. A total of 465 Heme Oxygenase (Decycling) 1 products are currently listed.
list all proteins Gene Name GeneID UniProt
HMOX1 3162 P09601
HMOX1 15368 P14901
HMOX1 24451 P06762

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Heme Oxygenase (Decycling) 1 Proteins (HMOX1) by Origin

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Top referenced Heme Oxygenase (Decycling) 1 Proteins

  1. Rat (Rattus) HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN1686745 : Brydun, Watari, Yamamoto, Okuhara, Teragawa, Kono, Chayama, Oshima, Ozono: Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis. in Hypertension research : official journal of the Japanese Society of Hypertension 2007 (PubMed)
    Show all 5 references for ABIN1686745

  2. Human HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN666727 : Soares, Brouard, Smith, Bach: Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs. in Immunological reviews 2002 (PubMed)
    Show all 2 references for ABIN666727

More Proteins for Heme Oxygenase (Decycling) 1 Interaction Partners

Soybean (Glycine max) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. study evaluated the time-course of HO-1 and catalase (show CAT Proteins) gene expressions in nodules and roots of soybean plants subjected to cadmium treatment

Xenopus laevis Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Data suggest expression of hsp32 is up-regulated in kidney epithelial cells upon in vitro exposure to heavy metal water pollutants (Cd, As) or proteasomal inhibitors (MG132, withaferin A, celastrol); heat shock may be synergistic factor.

Zebrafish Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. The induced expression of HO-1 by fenofibrate appeared to be essential for mediating the protective effects of fenofibrate, as the inhibition of HO-1 activity significantly diminished the protective effects of fenofibrate against the GM-mediated death of sensory hair cells in cochlea

  2. Suggest that Gata-1 (show GATA1 Proteins) and Nrf2a (show NFE2L2 Proteins) play differential roles in regulating the heme degradation enzymes hmox1a/bvra (show BLVRA Proteins)/bvrb (show BLVRB Proteins) during an early developmental period of heightened cellular stress.

  3. Bach1 (show BACH1 Proteins) regulates the liver specificity and transience of the Nrf2a (show NFE2L2 Proteins)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Proteins) inhibition based on its level in each tissue.

Arabidopsis thaliana Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Data indicate that Heme oxygenase 1 (HY1) functioned negatively and acted upstream of ABSCISIC ACID-INSENSITIVE4 (ABI4) in drought signaling.

  2. HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis.

  3. Data indicate that AtHO1 (HY1; heme oxygenase-1)-overexpressing plants generated more NO, whereas knock-down of AtHO1 expression reduced the level of nitric oxide (NO) in plants.

  4. HY1 mutant exhibited progressive salt hypersensitivity.

  5. Disrupting the binding of the AtHBP5 to haem oxygenase 1 (HY1) leads to oxidative stress.

  6. Mutation of HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence.

  7. HY1 and HY5 additively regulate the expression of light regulated genes and accumulation of chlorophyll and anthocyanin during early seedling development.

  8. HY1 (Heme oxygenase 1) plays an important role in salt acclimation.

  9. all members of the HO1 subfamily (HY1, HO3 and HO4) are active monomeric HOs and can convert haem to BV IXalpha using spinach Fd (ferredoxin) as an electron donor

Synechocystis PCC 6803 Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. HO2 (show HMOX2 Proteins) has an activity high enough to substitute for HO1 under aerobic conditions.

Human Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. TGFB1 (show TGFB1 Proteins) stimulated the expression of HO-1 via activating the PLCgamma/PKCalpha (show PKCa Proteins) pathway and suppressing the downstream expression of miRNA-519b.

  2. HO1, a protective heat shock protein, was significantly reduced in peripheral artery disease patients (0.8+/-0.7 vs. 3.4+/-1.3 ng/ml; P<0.001).

  3. Patients with severe preeclampsia may be protected against oxidative injury following an elevation in HO-1 and Nrf2 (show GABPA Proteins) levels.

  4. the expression of NRF2 (show GABPA Proteins), KEAP1 (show KEAP1 Proteins), NQO-1 (show NQO1 Proteins) and HO-1 are increased significantly in advanced laryngeal squamous cell carcinoma, compared with the adjacent normal mucosa. Remarkable relevance exists between high expression of KEAP1 (show KEAP1 Proteins), NQO-1 (show NQO1 Proteins), HO-1 and nuclear NRF2 (show GABPA Proteins). their expression levels were independent of age, tumor stage (clinical stage III and IV), tumor size and lymph node metastasis.

  5. Expressions of p38MAPK (show MAPK14 Proteins)-1, HIF-1 (show HIF1A Proteins) and HO-1 could serve as predictive roles for coronary lesions among peri (show PLIN1 Proteins)-menopausal women.

  6. we propose that upregulation of HO1 expression by a smallmolecule activator may be effective in controlling SexHinduced cell migration in lung cancer.

  7. (i) melatonin counteracted UVR-induced alterations in the ATP synthesis and reduced free radical formation; (ii) melatonin induced the translocation of Nrf2 (show GABPA Proteins) transcription factor from the cytosol into the nucleus resulting in, (iii) melatonin enhanced gene expression of phase-2 antioxidative enzymes including gamma-glutamylcysteine synthetase (show GCLC Proteins) (gamma-GCS (show GCLC Proteins)), heme oxygenase-1 (HO-1), and NADPH (show NQO1 Proteins): quinone dehydrogenase-1 (NQO1 (show NQO1 Proteins)...

  8. in GCB (show GBA Proteins)-DLBCL cells with low levels of NF-kappaB (show NFKB1 Proteins) expression, the TNF-alpha (show TNF Proteins)-mediated activation of NF-kappaB (show NFKB1 Proteins) leading to HO-1 upregulation rescued the cells from apoptosis caused by HO-1 silencing. These results indicated that HO-1 can be a potential target for the treatment of ABC (show ABCB6 Proteins)-DLBCL.

  9. Antioxidant, S-propyl-cysteine protects against NAFLD via PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins)/Nrf2 (show GABPA Proteins)/HO-1 signaling pathway.

  10. NRF2 (show GABPA Proteins) rs6721961 polymorphism was negatively associated with diabetes in Mexican men.

Pig (Porcine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. findings collectively suggest that miR (show MYLIP Proteins)-506 acts as a tumor suppressor via regulation of ROCK1 (show ROCK1 Proteins) expression and may thus be a promising therapeutic target for HCC (show FAM126A Proteins)

  2. Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.

  3. Down-regulation of HO-1 is associated with pulmonary arterial hypertension and right ventricular failure.

  4. The study revealed the involvement of HO-1 in classical swine fever virus proliferation.

  5. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  6. Glutamate (show GRIN2C Proteins) regulates Ca2 (show CA2 Proteins)+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms.

  7. obalt protoporphyrin prevents postictal cerebral vascular dysfunction by upregulating HO-1.

  8. Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF (show VEGFA Proteins), a specific endothelial cell growth factor (show FGF1 Proteins).

  9. Interaction of soluble factors in plasma possibly generated during PICSO are not responsible for upregulation of HO-1 and VEGF mRNA.

Cow (Bovine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. the data were consistent with HO-1 acting as an anti-viral factor and these findings suggested that induction of HO-1 may be a useful prevention and treatment strategy against BVDV infection.

  2. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 (show NFE2L2 Proteins) expression early in the course of infection, which results in increased expression of HO-1 within these cells.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: regulation of HO-1 gene expression in aortic endothelial cells by advanced glycation end products

  4. Sickle blood increases endothelial heme oxygenase activity.

  5. data provide evidence for the involvement of the thioredoxin/thioredoxin (show TXN Proteins) receptor system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge

  6. Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD/SOD3 (show SOD3 Proteins).

Mouse (Murine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Angiotensinogen (show AGT Proteins)-mediated downregulation of aquaporin 1 (show AQP1 Proteins) and Nrf2 (show NFE2L2 Proteins) signalling may play an important role in intrarenal renin (show REN Proteins)-angiotensin system-induced hypertension and kidney injury.

  2. loss of HO-1 in adipocytes has greater effects on body fat and fasting hyperglycemia in a sex-dependent fashion and that expression of HO-1 in adipose tissue may have a greater protective role in females as compared to males.

  3. Oleanolic acid can attenuate hepatic ischemia reperfusion injury via HO-1/Sesn2 (show SESN2 Proteins) signaling pathway.

  4. The results indicate that MHE exerts anti-inflammatory effects by suppressing inflammatory mediator production via NF-kappaB (show NFKB1 Proteins) and MAPK (show MAPK1 Proteins) signaling pathways inhibition and induction of HO-1 expression in macrophages. Therefore, our results suggest the potential value of MHE as an inflammatory therapeutic agent developed from a natural substance.

  5. HO-1/Carbon Monoxide can act as an antiresorption agent and reduce bone loss by blocking osteoclast differentiation.

  6. that miR (show MLXIP Proteins)-93 antagomir alleviates ischemic injury through the nuclear factor erythroid 2-related factor (Nrf2 (show NFE2L2 Proteins)) and heme oxygenase-1 (HO-1) antioxidant pathway

  7. Antioxidant, S-propyl-cysteine protects against NAFLD via PI3K/Akt (show AKT1 Proteins)/Nrf2 (show NFE2L2 Proteins)/HO-1 signaling pathway.

  8. HO-1 is an inhibitor of hematopoietic cell migration in response to crucial bone marrow homing chemoattractants.

  9. Data indicate that heme oxygenase-1 (HO-1)-mediated downregulation of NF-kappa B (show NFKB1 Proteins) p65 (show NFkBP65 Proteins) was involved in the anti-psoriatic effect of Terminalia chebulanin (TC).

  10. HO-1 was upregulated in spinal cord microglial cells after spinal nerve injury.

Rabbit Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Ligustrazine injection possesses notable protective effects on ischemia/reperfusion injury in rabbits by increasing the expression of HO-1 in lung.

  2. Results add new evidence for the importance of HO-1 in the genesis and development of atherosclerosis and provide several possible mechanisms underlying the anti-atherosclerosis effects of HO-1

  3. the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism

  4. Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 (show HSP70 Proteins) expression and increasing CO production.

  5. These results suggest that HO-1 is important in limiting in-stent stenosis and can be regarded as a new therapeutic target.

  6. Statins showed anti-atherosclerotic effects mediated by HO-1/eNOS (show NOS3 Proteins), restoring the [NO]/[ONOO(-)] imbalance and reducing lipid peroxidation.

  7. HO-1/CO system was activated and may be one of the protective signal pathway during pulmonary ischemia-reperfusion injury in rabbits.

  8. HO-1 contributes to vascular repair by increasing circulating endothelial progenitor cells (EPCs) derived from the bone marrow.

Heme Oxygenase (Decycling) 1 (HMOX1) Protein Profile

Protein Summary

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

Alternative names and synonyms associated with Heme Oxygenase (Decycling) 1 (HMOX1)

  • heme oxygenase (decycling) 1 (HMOX1)
  • heme oxygenase 1 (HO1)
  • heme oxygenase (decycling) 1 (hmox1)
  • heme oxygenase 1 (TED4)
  • heme oxygenase (ho1)
  • heme oxygenase (CPE0214)
  • heme oxygenase 1 (ho1)
  • Heme oxygenase (ho1)
  • heme oxygenase 1 (AM1_C0205)
  • heme oxygenase 1 (CC1G_11686)
  • heme oxygenase 1 (CpipJ_CPIJ007246)
  • Heme oxygenase (Cyan7425_2962)
  • heme oxygenase (decycling) 1 (Hmox1)
  • ATHO1 protein
  • bK286B10 protein
  • D8Wsu38e protein
  • F18A8.4 protein
  • F18A8_4 protein
  • GUN2 protein
  • HEME OXYGENASE protein
  • HEME OXYGENASE 1 protein
  • HEME OXYGENASE 6 protein
  • Hemox protein
  • Heox protein
  • HEOXG protein
  • Hmox protein
  • Hmox1 protein
  • HMOX1D protein
  • Ho-1 protein
  • Ho1 protein
  • hsp32 protein
  • HY1 protein
  • HY6 protein
  • MGC132176 protein
  • wu:fc27c04 protein
  • zgc:65984 protein

Protein level used designations for HMOX1

heme oxygenase (decycling) 1 , heme oxygenase 1 , fc27c04 , heme oxygenase , Heme oxygenase , heat shock protein, 32-kD , HO-1 , heat shock protein 32 , heme oxygenase (decyclizing) 1 , P32 protein , hemoxygenase , heme oxygenase-1

470195 Pan troglodytes
547612 Glycine max
719266 Macaca mulatta
734976 Xenopus laevis
791518 Danio rerio
817208 Arabidopsis thaliana
953483 Synechocystis sp. PCC 6803
988459 Clostridium perfringens str. 13
1012610 Thermosynechococcus elongatus BP-1
1463132 Prochlorococcus marinus subsp. marinus str. CCMP1375
1726356 Prochlorococcus marinus subsp. pastoris str. CCMP1986
1732486 Synechococcus sp. WH 8102
4718538 Prochlorococcus marinus str. AS9601
4719905 Prochlorococcus marinus str. MIT 9515
4778405 Prochlorococcus marinus str. MIT 9303
4779884 Prochlorococcus marinus str. NATL1A
4911675 Prochlorococcus marinus str. MIT 9301
5157291 Synechococcus sp. RCC307
5615689 Prochlorococcus marinus str. MIT 9215
5686060 Acaryochloris marina MBIC11017
5730157 Prochlorococcus marinus str. MIT 9211
5862292 Microcystis aeruginosa NIES-843
6012319 Coprinopsis cinerea okayama7130
6039118 Culex quinquefasciatus
7288894 Cyanothece sp. PCC 7425
3162 Homo sapiens
445512 Sus scrofa
513221 Bos taurus
15368 Mus musculus
24451 Rattus norvegicus
442987 Canis lupus familiaris
100715748 Cavia porcellus
396287 Gallus gallus
100173339 Pongo abelii
100008919 Oryctolagus cuniculus
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