Browse our IRX2 Proteins (IRX2)

Full name:
Iroquois Homeobox Protein 2 Proteins (IRX2)
On are 4 Iroquois Homeobox Protein 2 (IRX2) Proteins from 3 different suppliers available. Additionally we are shipping IRX2 Antibodies (51) and many more products for this protein. A total of 63 IRX2 products are currently listed.
Irx5, IRX6, IRXA2
list all proteins Gene Name GeneID UniProt
IRX2 153572 Q9BZI1
Rat IRX2 IRX2 306657  
IRX2 16372 P81066

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IRX2 Proteins (IRX2) by Origin

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More Proteins for IRX2 Interaction Partners

Human Iroquois Homeobox Protein 2 (IRX2) interaction partners

  1. IRX2 transcription factor might represent a novel metastasis associated protein that acts as a negative regulator of cellular motility and as a repressor of chemokine (show CCL1 Proteins) expression and loss of IRX2 expression could therefore contribute to early hematogenous dissemination of breast cancer by sustaining chemokine (show CCL1 Proteins) secretion and enabling mobilization of tumor cells.

  2. IRX2 modulates the expression levels of MMP2 and VEGF in an AKTdependent manner.

  3. The mechanism by which IRX2 promoted cell proliferation and invasion by activating AKT (show AKT1 Proteins) and MMP9 (show MMP9 Proteins) was detected.

  4. Results revealed 3 genes highly predictive of event-free survival (EFS), beyond age and MLL status: FLT3, IRX2, and TACC2.

  5. IRX2 represents a candidate target of 5p amplifications in soft tissue sarcomas and might play a crucial role during the progression of this disease.

Mouse (Murine) Iroquois Homeobox Protein 2 (IRX2) interaction partners

  1. generation and phenotypic analysis of an Irx2-deficient mouse strain. Irx2-deficient mice are viable, are fertile, and appear to be normal.

  2. This homeobox protein (show HOXA1 Proteins) is expressed during early lung development.

  3. This homeobox protein (show HOXA1 Proteins) is expressed during digit development.

IRX2 Protein Profile

Protein Summary

IRX2 is a member of the Iroquois homeobox gene family. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.

Alternative names and synonyms associated with IRX2

  • iroquois homeobox 2 (IRX2)
  • iroquois homeobox 2 (Irx2)
  • Iroquois related homeobox 2 (Drosophila) (Irx2)
  • Irx5 protein
  • IRX6 protein
  • IRXA2 protein

Protein level used designations for IRX2

homeodomain protein IRXA2 , iroquois homeobox protein 2 , iroquois-class homeodomain protein IRX-2 , Iroquois related homeobox 2 , Iroquois related homeobox 5 , iroquois-class homeobox protein Irx6

153572 Homo sapiens
488064 Canis lupus familiaris
306657 Rattus norvegicus
16372 Mus musculus
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