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Browse our anti-SETD2 (SETD2) Antibodies

Full name:
anti-SET Domain Containing 2 Antibodies (SETD2)
On www.antibodies-online.com are 71 SET Domain Containing 2 (SETD2) Antibodies from 13 different suppliers available. Additionally we are shipping and many more products for this protein. A total of 76 SETD2 products are currently listed.
Synonyms:
HBP231, HIF-1, HIP-1, HYPB, Kif9, KMT3A, p231HBP, SET2
list all antibodies Gene Name GeneID UniProt
SETD2 316013  
SETD2 29072 Q9BYW2
SETD2    

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Most Popular Reactivities for anti-SETD2 (SETD2) Antibodies

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anti-Rat (Rattus) SETD2 Antibodies:

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anti-Mouse (Murine) SETD2 Antibodies:

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Top referenced anti-SETD2 Antibodies

  1. Cow (Bovine) Polyclonal SETD2 Primary Antibody for IHC, WB - ABIN2783051 : Barrand, Andersen, Collas: Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes. in Biochemical and biophysical research communications 2010 (PubMed)

  2. Mouse (Murine) Polyclonal SETD2 Primary Antibody for ELISA, WB - ABIN262286 : Sun, Wei, Wu, Hu, Wang, Wang, Zhang, Chen, Huang, Chen: Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase. in The Journal of biological chemistry 2005 (PubMed)

  3. Human Polyclonal SETD2 Primary Antibody for ICC, IF - ABIN4320758 : Kanu, Grönroos, Martinez, Burrell, Yi Goh, Bartkova, Maya-Mendoza, Mistrík, Rowan, Patel, Rabinowitz, East, Wilson, Santos, McGranahan, Gulati, Gerlinger, Birkbak, Joshi, Alexandrov, Stratton, Powles et al.: SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair. ... in Oncogene 2015 (PubMed)

More Antibodies against SETD2 Interaction Partners

Human SET Domain Containing 2 (SETD2) interaction partners

  1. SPOP (show SPOP Antibodies)-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing.

  2. one of these mutations (R2510H), located in the Set2 Rpb1 (show POLR2A Antibodies) interaction domain, did not result in an observable defect in SETD2 enzymatic function, a second mutation in the catalytic domain of this enzyme (R1625C) resulted in a complete loss of histone H3 (show HIST3H3 Antibodies) Lys (show LYZ Antibodies)-36 trimethylation (H3K36me3).

  3. functional loss of SETD2 enables renal primary tubular epithelial cells to bypass the senescence barrier by maintaining CDKN2A (show CDKN2A Antibodies)-E2F (show E2F1 Antibodies) signaling, facilitating a malignant transformation toward Clear Cell Renal Cell Carcinoma (show MOK Antibodies).

  4. Mutation in SETD2 gene is associated with renal cell carcinoma (show MOK Antibodies).

  5. Data identify SETD2 as a dual-function methyltransferase for both chromatin and the cytoskeleton and show a requirement for methylation in maintenance of genomic stability and the integrity of both the tubulin (show TUBB Antibodies) and histone codes.

  6. This study provides evidence for HOTAIR to promote tumorigenesis via downregulating SETD2 in liver cancer stem cells.

  7. Use bioinformatic tools to predict the molecular effects of all mutations lying in SETD2 genes.

  8. This study provide the evidence SETD2 mutation releate to Autism Spectrum Disorder.

  9. Data show that SETD2 mutations are not associated with microsatellite instability in renal cancer and suggest a role for SETD2 in maintaining genome integrity through nucleosome stabilization, DNA repair and suppression of replication stress.

  10. Findings extend the knowledge about the regulation of SETD2 at the posttranscriptional level by miRNA and regulatory mechanism downstream of SETD2 in ccRCC.

SETD2 Antigen Profile

Antigen Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

Alternative names and synonyms associated with SETD2

  • SET domain containing 2 (Setd2) antibody
  • SET domain containing 2 (SETD2) antibody
  • HBP231 antibody
  • HIF-1 antibody
  • HIP-1 antibody
  • HYPB antibody
  • Kif9 antibody
  • KMT3A antibody
  • p231HBP antibody
  • SET2 antibody

Protein level used designations for SETD2

histone-lysine N-methyltransferase SETD2 , kinesin family member 9 , huntingtin interacting protein 1 , huntingtin yeast partner B , huntingtin-interacting protein B , lysine N-methyltransferase 3A

GENE ID SPECIES
316013 Rattus norvegicus
476643 Canis lupus familiaris
29072 Homo sapiens
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