SETD2 antibody (SET Domain Containing 2) (N-Term)

Details for Product anti-SETD2 Antibody No. ABIN2783051
Antigen
Epitope
N-Term
15
8
8
8
7
7
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Rat (Rattus)
75
18
15
2
1
1
Host
Rabbit
62
9
7
Clonality
Polyclonal
Conjugate
This SETD2 antibody is un-conjugated
6
4
4
4
4
4
2
2
2
2
2
2
Application
Immunohistochemistry (IHC), Western Blotting (WB)
41
39
37
16
6
4
3
2
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SETD2
Sequence SDEDSVRTSS SQRSHDLKFS ASIEKERDFK KSSAPLKSED LGKPSRSKTD
Cross-Reactivity Dog (Canine), Human, Rat (Rattus)
Predicted Reactivity Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 83%, Rat: 85%
Characteristics This is a rabbit polyclonal antibody against SETD2. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Antigen
Alternative Name SETD2 / HIF1 (SETD2 Antibody Abstract)
Background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Alias Symbols: FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP
Protein Interaction Partner: CLK2, SOX2, CBX8, HCVgp1, SIAH2, SMAD3, CIC, ATXN1, ELAVL1, UBC, SETD2, HIST1H3A, POLR2A, TP53, IWS1, HTT,
Protein Size: 891
Molecular Weight 97 kDa
Gene ID 29072
NCBI Accession NM_014159
UniProt Q9BYW2
Pathways Tube Formation
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 891 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-SET Domain Containing 2 (SETD2) (N-Term) antibody (ABIN2783051) anti-SET Domain Containing 2 (SETD2) (N-Term) antibody (Image 1)
Image no. 2 for anti-SET Domain Containing 2 (SETD2) (N-Term) antibody (ABIN2783051) SETD2 antibody - N-terminal region validated by IHC using Human Placenta lysate at 4...
Image no. 3 for anti-SET Domain Containing 2 (SETD2) (N-Term) antibody (ABIN2783051) Human HepG2 cells SETD2 is strongly supported by BioGPS gene expression data to be ex...
Product cited in: Barrand, Andersen, Collas: "Promoter-exon relationship of H3 lysine 9, 27, 36 and 79 methylation on pluripotency-associated genes." in: Biochemical and biophysical research communications, Vol. 401, Issue 4, pp. 611-7, 2010 (PubMed).