Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. SETD2 is a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs.
Alias Symbols: FLJ16420, FLJ22472, FLJ23184, FLJ45883, HIF-1, HSPC069, HYPB, KIAA1732, KMT3A, SET2, HIP-1, HBP231, p231HBP
Protein Interaction Partner: CLK2, SOX2, CBX8, HCVgp1, SIAH2, SMAD3, CIC, ATXN1, ELAVL1, UBC, SETD2, HIST1H3A, POLR2A, TP53, IWS1, HTT,
Protein Size: 891