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Human CTNNB1 ELISA Kit for Sandwich ELISA - ABIN832441
Gaudio, Privitera, Battaglia, Torrisi, Sidoti, Pulvirenti, Canzonieri, Tringali, Fiore: Sclerostin levels associated with inhibition of the Wnt/?-catenin signaling and reduced bone turnover in type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2012
Rat (Rattus) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN431880
Shao, Cai, Sheng, Yin: Role of SDF-1 and Wnt signaling pathway in the myocardial fibrosis of hypertensive rats. in American journal of translational research 2015
Mouse (Murine) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN424163
Chen, Feng, Bao, Li, Zhang, Shen, Zhao, Guo, Jing, Lin, Zong: Adverse Effects of Osteocytic Constitutive Activation of ß-Catenin on Bone Strength and Bone Growth. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
These results support the notion that pharmacological modulation of beta-catenin can be used to treat pseudarthrosis in patients with neurofibromatosis type 1 (show NF1 ELISA Kits).
we revealed miR (show MLXIP ELISA Kits)-375-3p negatively regulated osteogenesis by targeting LRP5 (show LRP5 ELISA Kits) and beta-catenin
ARX positively regulates Wnt (show WNT2 ELISA Kits)/ beta-catenin signaling and the C-terminal domain of ARX interacts with the armadillo (show PKP1 ELISA Kits) repeats in beta-catenin to promote Wnt (show WNT2 ELISA Kits)/beta-catenin signaling. In addition, we found BCL9 (show BCL9 ELISA Kits) and P300 (show NOTCH1 ELISA Kits) also interact with ARX to modulate Wnt (show WNT2 ELISA Kits)/beta-catenin signaling.
our results are consistent with an epithelial proliferative growth mechanism linking CTNNB1-driven Ccnd1 (show CCND1 ELISA Kits) transcription and estrogen-mediated CCND1 (show CCND1 ELISA Kits) protein stabilization.
Rbm46 regulates mouse embryonic stem cell differentiation through down-regulation of beta-Catenin.Rbm46 regulates mouse embryonic stem cell differentiation by targeting beta-Catenin mRNA for degradation.
Beta-catenin may promote bacterial killing via suppression of P. aeruginosa-induced macrophage autophagy.
Data suggest that PKCe (show PRKCE ELISA Kits) positively regulates beta-catenin expression and stabilization in a glycogen synthase kinase 3beta-independent manner; beta-catenin exhibits a perinuclear localization pattern in podocytes; however, beta-catenin is predominantly localized to nucleus in podocytes from PKCe (show PRKCE ELISA Kits) knockout mice. (PKCe (show PRKCE ELISA Kits) = protein kinase C epsilon (show PRKCE ELISA Kits))
Leukocyte beta-catenin expression is disturbed in systemic lupus erythematosus in patients and lupus-prone mice.
We have identified cooperation of hMet and beta-catenin activation in a subset of hepatocellular cancer patients and modeled this human disease in mice with a significant transcriptomic intersection; this model will provide novel insight into the biology of this tumor and allow us to evaluate novel therapies as a step toward precision medicine
GLP-1 (show GCG ELISA Kits) promoted adipogenesis through the modulation of the Wnt4 (show WNT4 ELISA Kits)/beta-catenin signaling pathway
Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.
Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 ELISA Kits) pathway, therefore suggesting a possible role for Wnt (show WNT2 ELISA Kits) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (show MYLIP ELISA Kits)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (show WNT2 ELISA Kits) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (show WNT2 ELISA Kits)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (show WNT2 ELISA Kits) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (show WNT2 ELISA Kits) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 and Eaf2 (show EAF2 ELISA Kits) in inhibiting canonical Wnt (show WNT2 ELISA Kits)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 (show EAF2 ELISA Kits) tumor suppressor activity.
Ccr7 (show CCR7 ELISA Kits) functions during axis formation as a GPCR (show GPRC6A ELISA Kits) to inhibit beta-catenin, likely by promoting Ca(2 (show CA2 ELISA Kits)+) transients throughout the blastula.
ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.
Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A and thereby down-regulating the Wnt (show WNT2 ELISA Kits)/beta-catenin signaling.
maternal Wnt (show WNT2 ELISA Kits)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (show WNT2 ELISA Kits) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC ELISA Kits), Axin (show AXIN1 ELISA Kits) and GSK3 (show GSK3b ELISA Kits), although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (show AKT1 ELISA Kits) polarization depend specifically on the N-cadherin (show CDH2 ELISA Kits)-p120 catenin (show CTNND1 ELISA Kits) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 ELISA Kits)-beta-catenin complex.
HERG (show KCNH2 ELISA Kits) channel activity is stimulated by beta-catenin
Zic3 (show ZIC3 ELISA Kits) can suppress Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch (show NOTCH1 ELISA Kits) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (show GSK3b ELISA Kits)
The tyrosine kinase receptor (show KDR ELISA Kits), PTK7 (show PTK7 ELISA Kits), is implicated in beta-catenin-dependent developmental processes.
Kazrin (show KAZ ELISA Kits) interacts with ARVCF (show ARVCF ELISA Kits)-catenin, spectrin and p190B (show ARHGAP5 ELISA Kits) RhoGAP (show ARHGAP1 ELISA Kits), and modulates RhoA (show RHOA ELISA Kits) activity.
TSPAN2 (show TSPAN2 ELISA Kits) may promote apoptosis of RNAKT-15 cells by regulating the JNK (show MAPK8 ELISA Kits)/beta-catenin pathway in response to high glucose concentrations. Targeting TSPAN2 (show TSPAN2 ELISA Kits) could be a potential therapeutic strategy to treat glucose toxicity-induced beta-cell failure.
Case Reports/Review: CTNNB1 point-mutations/deletion mutations in ovarian microcystic stromal tumors.
UBQLN4, APP (show APP ELISA Kits), CTNNB1, SHBG (show SHBG ELISA Kits), and COL1A1 (show COL1A1 ELISA Kits) might be involved in the development of nonalcoholic fatty liver disease, and are proposed as the potential markers for predicting the development of this condition
Our findings suggest that Pyk2 (show PTK2B ELISA Kits) plays an important role in the coordination of stabilization of beta-catenin in the crosstalk between Wnt (show WNT2 ELISA Kits)/beta-catenin and Wnt (show WNT2 ELISA Kits)/Ca(2 (show CA2 ELISA Kits)+) signaling pathways upon Wnt3a (show WNT3A ELISA Kits) stimulation in differentiating hNPCs.
Data show that in colorectal cancer SerpinB3 (show SERPINB3 ELISA Kits), COX-2 (show COX2 ELISA Kits) and beta-Catenin are positively correlated and associated with more advanced tumor stage.
DDX17 (show DDX17 ELISA Kits) contributes to acquired gefitinib resistance through exportin (show XPO1 ELISA Kits)/importin (show KPNA4 ELISA Kits)-dependent cytoplasmic shuttling and activation of beta-catenin in non-small lung cancer cells.
An extended immunohistochemical panel that includes beta-catenin and SOX10 (show SOX10 ELISA Kits) helps to support the diagnosis of biphenotypic sinonasal sarcoma without the need for gene rearrangement studies.
All substances, nilotinib, dasatinib, erlotinib and gefitinib have a significant impact on beta-catenin and E-cadherin (show CDH1 ELISA Kits) expression in both HPV16-positive and HPV16-negative cells in vitro. Hence, alterations of beta-catenin and E-cadherin (show CDH1 ELISA Kits) could provide novel insights for future targeted therapies of head and neck SCC (show CYP11A1 ELISA Kits)
Low CTNNB1 expression is associated with Metastasis in Colorectal Cancer.
NF-kappaB (show NFKB1 ELISA Kits) and beta-catenin signaling by gain-of-function mutations in CARMA1 (show CARD11 ELISA Kits) augments WNT (show WNT2 ELISA Kits) stimulation and is required for regulating the expression of distinct NF-kappaB (show NFKB1 ELISA Kits) target genes to trigger cell-intrinsic and extrinsic processes that promote DLBCL lymphomagenesis
Results highlight a potential role for the beta-catenin/Wnt (show WNT2 ELISA Kits) and Notch (show NOTCH1 ELISA Kits) signalling pathways during the infection of crypt cells by L. intracellularis.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (show WNT3A ELISA Kits) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (show MYOCD ELISA Kits)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 ELISA Kits)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (show WNT3A ELISA Kits) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 ELISA Kits)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (show TNF ELISA Kits) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.
These results demonstrate that activation of AKT (show AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (show BRD2 ELISA Kits) regulates CTNNB1 protein and WNT2 (show WNT2 ELISA Kits) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 ELISA Kits) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 ELISA Kits) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (show TGFB3 ELISA Kits) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta (show GSK3b ELISA Kits)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 ELISA Kits)/beta-catenin and Hedgehog (show SHH ELISA Kits) signaling
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin