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Human CTNNB1 ELISA Kit for Sandwich ELISA - ABIN416829
Gupta, Khan, Kumar, Kumar, Sharma: Versican and its associated molecules: potential diagnostic markers for multiple myeloma. in Clinica chimica acta; international journal of clinical chemistry 2015
Rat (Rattus) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN431880
Shao, Cai, Sheng, Yin: Role of SDF-1 and Wnt signaling pathway in the myocardial fibrosis of hypertensive rats. in American journal of translational research 2015
Mouse (Murine) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN424163
Chen, Feng, Bao, Li, Zhang, Shen, Zhao, Guo, Jing, Lin, Zong: Adverse Effects of Osteocytic Constitutive Activation of ß-Catenin on Bone Strength and Bone Growth. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
Sphingosylphosphorylcholine promotes the differentiation of resident Sca-1 (show Ly6a ELISA Kits) positive cardiac stem cells to cardiomyocytes through lipid raft/JNK (show MAPK8 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) and beta-catenin signaling pathways.
Data indicate that a balance between supporting cell (show PTPRJ ELISA Kits) self-renewal and differentiation is maintained in the developing ovary by relative Wnt4 (show WNT4 ELISA Kits) protein/beta-catenin and p27Kip1 (show CDKN1B ELISA Kits) protein (p27 (show CDKN1B ELISA Kits))/Forkhead box L2 (FOXL2 (show FOXL2 ELISA Kits)) activities.
After ERbeta interference, beta-catenin, p-Gsk3beta (Ser9) and CyclinDl were strongly expressed compared with expressions in the blank control group
Sp5/8 bind directly to GC boxes in Wnt (show WNT2 ELISA Kits) target gene enhancers and to adjacent, or distally positioned, chromatin-bound T-cell factor (Tcf) 1 (show HNF1A ELISA Kits)/lymphoid enhancer factor (Lef) 1 (show LEF1 ELISA Kits) to facilitate recruitment of beta-catenin to target gene enhancers.
Epithelial expression of DeltaN(1-131)-beta-catenin in the intestine creates an inflammatory microenvironment and co-operates with other mutations in the Wnt (show WNT2 ELISA Kits)/beta-catenin pathway to facilitate and promote tumorigenesis.
detected a marked increase in the localization of beta-catenin in the nucleus of crypt epithelial cells in the ileum of PKD1 (show PKD1 ELISA Kits)
Our findings identify the eIF4E (show EIF4E ELISA Kits)- beta-catenin axis as a critical regulator of lung cancer cell growth and survival, and suggest that its pharmacological inhibition may be therapeutically useful in lung cancer.
The role of beta-catenin signaling in the proliferation of undifferentiated spermatogonia in the adult mouse testis
Beta-catenin signaling role in the hair follicle bulge stem cells
Inducible endothelial-cell-restricted disruption of ctnnb1 caused BBB (show ALMS1 ELISA Kits) breakdown and downregulation of claudin-1 (show CLDN1 ELISA Kits) and -3, leading to seizures, neuronal injury, multiple brain petechial hemorrhages, CNS inflammation, and postictal death.
Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 ELISA Kits) pathway, therefore suggesting a possible role for Wnt (show WNT2 ELISA Kits) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (show MYLIP ELISA Kits)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (show WNT2 ELISA Kits) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (show WNT2 ELISA Kits)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (show WNT2 ELISA Kits) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (show WNT2 ELISA Kits) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 and Eaf2 (show EAF2 ELISA Kits) in inhibiting canonical Wnt (show WNT2 ELISA Kits)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 (show EAF2 ELISA Kits) tumor suppressor activity.
Ccr7 (show CCR7 ELISA Kits) functions during axis formation as a GPCR (show GPRC6A ELISA Kits) to inhibit beta-catenin, likely by promoting Ca(2 (show CA2 ELISA Kits)+) transients throughout the blastula.
ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.
2-OST (show HS2ST1 ELISA Kits) functions within the Wnt (show WNT2 ELISA Kits) pathway, downstream of Wnt (show WNT2 ELISA Kits) ligand signaling and upstream of Gsk3beta and beta-catenin intracellular localization and function
maternal Wnt (show WNT2 ELISA Kits)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (show WNT2 ELISA Kits) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC ELISA Kits), Axin (show AXIN1 ELISA Kits) and GSK3, although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (show AKT1 ELISA Kits) polarization depend specifically on the N-cadherin (show CDH2 ELISA Kits)-p120 catenin (show CTNND1 ELISA Kits) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 ELISA Kits)-beta-catenin complex.
HERG (show KCNH2 ELISA Kits) channel activity is stimulated by beta-catenin
Zic3 (show ZIC3 ELISA Kits) can suppress Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3
The tyrosine kinase receptor (show KDR ELISA Kits), PTK7 (show PTK7 ELISA Kits), is implicated in beta-catenin-dependent developmental processes.
Kazrin (show KAZ ELISA Kits) interacts with ARVCF (show ARVCF ELISA Kits)-catenin, spectrin and p190B (show ARHGAP5 ELISA Kits) RhoGAP (show ARHGAP1 ELISA Kits), and modulates RhoA (show RHOA ELISA Kits) activity.
Activated Xenopus CTNNB1 regulates embryonic limb development via FGF signaling
Decreased inhibition of beta-catenin was correlated with aberrant parenchyma in idiopathic pulmonary fibrosis patients.
The TIPE2-elicited antimetastatic effect in gastric cancer was closely associated with the inhibition of AKT signaling and enhancement of GSK3b activity followed by the degradation and decreased translocation to nucleus of b-catenin
High CTNNB1 expression is associated with cancer.
Case Report: well-differentiated hepatocellular neoplasm with beta-catenin mutation and Dubin-Johnson like pigment.
Survivin (show BIRC5 ELISA Kits), p53 (show TP53 ELISA Kits), and beta-catenin overexpression, as prognostic markers, might suggest that the Urothelial carcinomas are biologically aggressive with the poor prognosis
Data suggest that beta-catenin (beta-cat) signaling upregulates the expression of osterix (OSX (show SP7 ELISA Kits)) in pre-osteoblastic and bone marrow stromal cells.
The results identify phosphorylated Y142 beta-catenin as a nuclear b-catenin signaling form that downregulates adhesion and promotes glioblastoma multiforme cell invasion.
study demonstrate that GDNF (show GDNF ELISA Kits) increases the intracellular phosphorylation level of beta-catenin through N-cadherin (show CDH2 ELISA Kits)/Src (show SRC ELISA Kits) signaling
Beta-catenin expression was increased in the vascular endothelial cells of primary myelofibrosis and in the megakaryocytes of Eessential thrombocytemia and policythemia vera (show IGF2BP3 ELISA Kits).
All trans-retinoic acid can reverse the suppressive effect of MED28 (show MED28 ELISA Kits) on HBP1 and E-cadherin (show CDH1 ELISA Kits) and inactivate the Wnt (show WNT2 ELISA Kits)/beta-catenin pathway in colorectal cancer, suggesting a protective effect of ATRA against colorectal cancer.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (show WNT3A ELISA Kits) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (show MYOCD ELISA Kits)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 ELISA Kits)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (show WNT3A ELISA Kits) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 ELISA Kits)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (show TNF ELISA Kits) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
These results demonstrate that activation of AKT (show AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (show BRD2 ELISA Kits) regulates CTNNB1 protein and WNT2 (show WNT2 ELISA Kits) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 ELISA Kits) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 ELISA Kits) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (show TGFB3 ELISA Kits) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin