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Human CTNNB1 ELISA Kit for Sandwich ELISA - ABIN416829
Gupta, Khan, Kumar, Kumar, Sharma: Versican and its associated molecules: potential diagnostic markers for multiple myeloma. in Clinica chimica acta; international journal of clinical chemistry 2015
Rat (Rattus) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN431880
Shao, Cai, Sheng, Yin: Role of SDF-1 and Wnt signaling pathway in the myocardial fibrosis of hypertensive rats. in American journal of translational research 2015
Mouse (Murine) CTNNB1 ELISA Kit for Sandwich ELISA - ABIN424163
Chen, Feng, Bao, Li, Zhang, Shen, Zhao, Guo, Jing, Lin, Zong: Adverse Effects of Osteocytic Constitutive Activation of ß-Catenin on Bone Strength and Bone Growth. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015
Human CTNNB1 ELISA Kit for Sandwich ELISA - ABIN832441
Gaudio, Privitera, Battaglia, Torrisi, Sidoti, Pulvirenti, Canzonieri, Tringali, Fiore: Sclerostin levels associated with inhibition of the Wnt/?-catenin signaling and reduced bone turnover in type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2012
temporal expression of CTNNB1 mRNA during dermal wound repair in the horse
receptor for advanced glycation end products (RAGE (show AGER ELISA Kits)) was required for stabilization of beta-catenin in toluene diisocyanate-induced asthma, identifying protective effects of RAGE (show AGER ELISA Kits) blockade in this mouse model
Axud1 mediated stress-induced cardiomyocytes apoptosis through activating Wnt (show WNT2 ELISA Kits)/beta-catenin signaling pathway.
Our findings are consistent with published reports wherein anterior taste buds have higher sweet sensitivity while posterior taste buds are better tuned to bitter, and suggest beta-catenin plays a greater role in renewal of anterior versus posterior taste buds.
Exogenous or paracrine sources of NO promote the specification towards the myocyte lineage and expression of cardiac sarcomeric proteins of adult cardiac progenitor cells. This is contingent upon the expression and activity of the alpha1 subunit of guanylyl cyclase in CPC that is necessary for NO-mediated inhibition of the canonical Wnt (show WNT2 ELISA Kits)/beta-catenin pathway.
AP-2 beta (show TFAP2B ELISA Kits) and beta-catenin interact both in vitro through GST pull-down assays and in vivo by co-immunoprecipitation. We further identified the interaction regions to the DNA-binding domain of AP-2 beta (show TFAP2B ELISA Kits) and the 1-9 Armadillo (show PKP1 ELISA Kits) repeats of beta-catenin.
TIEG1 is involved in regulating the canonical Wnt (show WNT2 ELISA Kits) signaling pathway in bone through multiple mechanisms of action.
Activation of WNT/b-catenin activity improved cardiac contractility and ameliorated intraventricular conduction defects in LmnaH222P/H222P mice, which was associated with increased expression of myocardial connexin 43. These results indicate that decreased WNT/b-catenin contributes to the pathophysiology of LMNA cardiomyopathy and that drugs activating b-catenin may be beneficial in affected individuals
Oncogenic beta-catenin and PI3K activities interact in the acquisition of multiple cancer-related phenotypes in organoids grown in Matrigel.
We further found that knockdown of Kif2a (show KIF2A ELISA Kits) decreased the protein level of b-catenin, which is a critical molecule for neocortical neurogenesis. Together, these results reveal an important function of Kif2a (show KIF2A ELISA Kits) in embryonic neocortical neurogenesis
Data show that both Wnt1 (show WNT1 ELISA Kits)-cre and P0-cre are similarly effective in deleting beta-catenin in the neural crest.
Mechanistically, Hif-3alpha2 binds to beta-catenin and destabilizes the nuclear beta-catenin complex.
Nuclear beta-catenin is an indication of an activated Wnt (show WNT2 ELISA Kits) pathway, therefore suggesting a possible role for Wnt (show WNT2 ELISA Kits) signalling during zebrafish tooth development and replacement.
Findings suggest that microRNA 19b (miR (show MYLIP ELISA Kits)-19b) regulates laterality development and heart looping in embryos by targeting beta-catenin ctnnb1.
Custos binds to beta-catenin in a Wnt (show WNT2 ELISA Kits) responsive manner without affecting its stability, but rather modulates the cytoplasmic to nuclear translocation of beta-catenin.
The role of the beta-catenin mechanosensitive pathway in mesoderm identity has been conserved over the large evolutionary distance separating zebrafish and Drosophila.
The Wnt (show WNT2 ELISA Kits)/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. (Review)
This study demonstrated that beta-catenin/Wnt (show WNT2 ELISA Kits) signaling is initially required to activate cell-cycle re-entry in Muller glia following injury and that Wnt (show WNT2 ELISA Kits) signaling subsequently controls the fate of the progeny of those cell divisions.
A novel role for Eaf1 and Eaf2 (show EAF2 ELISA Kits) in inhibiting canonical Wnt (show WNT2 ELISA Kits)/beta-catenin signaling, which might form the mechanistic basis for Eaf1 and Eaf2 (show EAF2 ELISA Kits) tumor suppressor activity.
Ccr7 (show CCR7 ELISA Kits) functions during axis formation as a GPCR (show GPRC6A ELISA Kits) to inhibit beta-catenin, likely by promoting Ca(2 (show CA2 ELISA Kits)+) transients throughout the blastula.
ctnnb1 and ctnnb2 regulate multiple processes of laterality development in zebrafish embryos through similar and distinct mechanisms.
Together, these results indicate that capsaicin inhibits the patterning of the dorso-ventral and anterior-posterior body axes of embryo by repressing PP2A and thereby down-regulating the Wnt (show WNT2 ELISA Kits)/beta-catenin signaling.
maternal Wnt (show WNT2 ELISA Kits)/STOP signaling, but not beta-catenin signaling, has a role in cleavage after fertilization and cell cycle progression
Wnt (show WNT2 ELISA Kits) signalling can benefit from nucleo-cytoplasmic shuttling of APC (show APC ELISA Kits), Axin (show AXIN1 ELISA Kits) and GSK3 (show GSK3b ELISA Kits), although they are in general beta-catenin antagonising proteins.
Phosphoinositide 3-kinase and Rac (show AKT1 ELISA Kits) polarization depend specifically on the N-cadherin (show CDH2 ELISA Kits)-p120 catenin (show CTNND1 ELISA Kits) complex, whereas myosin II light chain and actin filament polarization depend on the N-cadherin (show CDH2 ELISA Kits)-beta-catenin complex.
HERG (show KCNH2 ELISA Kits) channel activity is stimulated by beta-catenin
Zic3 (show ZIC3 ELISA Kits) can suppress Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and control development of the notochord and Spemann's organizer.
Notch (show NOTCH1 ELISA Kits) initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 (show GSK3b ELISA Kits)
The tyrosine kinase receptor (show KDR ELISA Kits), PTK7 (show PTK7 ELISA Kits), is implicated in beta-catenin-dependent developmental processes.
Kazrin (show KAZ ELISA Kits) interacts with ARVCF (show ARVCF ELISA Kits)-catenin, spectrin and p190B (show ARHGAP5 ELISA Kits) RhoGAP (show ARHGAP1 ELISA Kits), and modulates RhoA (show RHOA ELISA Kits) activity.
High beta catenin expression is associated with gastric cancer.
E-cadherin (show CDH1 ELISA Kits) and beta-catenin expression provides discriminative prognostic power independent of conventional pathologic factors, thus further reinforcing the important role of cell adhesion molecules in the process of tumor metastasis, especially in triple-negative breast cancer (TNBC).
High PROX1 (show PROX1 ELISA Kits) and beta-catenin expression were independent factors for better prognosis in pancreatic ductal adenocarcinoma.
estrogen may play a role in androgen-independent prostate cancer cell proliferation through a novel pathway, involving ERbeta (show ESR2 ELISA Kits)-mediated activation of beta-catenin.
High beta catenin expression is associated with familial adenomatous polyposis.
CTNNB1 mutations in Lynch syndrome are associated with invasive growth.
Data show that FERM domain-containing protein 5 (FRMD5) is regulated by both beta-catenin and transcription factor 7-Like 2 protein (TCF7L2) in colon cancer cells.
Suppression of Akt1 (show AKT1 ELISA Kits)-beta-catenin pathway in advanced prostate cancer promotes TGFbeta1 (show TGFB1 ELISA Kits)-mediated epithelial to mesenchymal transition and metastasis.
MiR (show MLXIP ELISA Kits)-770 inhibits tumorigenesis and EMT (show ITK ELISA Kits) by targeting JMJD6 (show JMJD6 ELISA Kits) and regulating WNT (show WNT2 ELISA Kits)/beta-catenin pathway in non-small cell lung cancer
Tanshinone IIA inhibits beta-catenin/VEGF (show VEGFA ELISA Kits)-mediated angiogenesis by targeting TGF-beta1 (show TGFB1 ELISA Kits) in normoxic and HIF-1alpha (show HIF1A ELISA Kits) in hypoxic microenvironments in human colorectal cancer.
Results highlight a potential role for the beta-catenin/Wnt (show WNT2 ELISA Kits) and Notch (show NOTCH1 ELISA Kits) signalling pathways during the infection of crypt cells by L. intracellularis.
Flutamide exposure led to decreased beta-catenin in corpus luteum of mid/late pregnancy.
beta-catenin signaling is involved in formation of contractile membranes by dedifferentiated retinal pigment epithelium cells.
Wnt3a (show WNT3A ELISA Kits) produced a significant increase in heart valve interstitial cell number at day 4 and in the percentage of BrdU-positive nuclei at 24 h. The increase in proliferation was abolished by beta-catenin siRNA.
beta-catenin controls myocardin (show MYOCD ELISA Kits)-related transcription factor-dependent transcription and emerges as a critical regulator of an array of cytoskeletal genes
beta-Catenin plays a critical role in mediating TGF-beta1 (show TGFB1 ELISA Kits)-induced myofibroblast differentiation in aortic valve interstitial cells.
scratching-induced injury and repair of bronchial epithelial cells may involve inhibition of Glycogen synthase kinase 3beta activity which can lead to activation of the downstream signaling through beta-catenin
Data show that Wnt3a (show WNT3A ELISA Kits) can inhibit the adipogenic differentiation of porcine AMSCs, and suggest that Wnt (show WNT2 ELISA Kits)/beta-catenin signaling inhibits adipogenic differentiation potential and alters the cell fate from adipocytes to osteoblasts.
TNF-alpha (show TNF ELISA Kits) inhibits adipogenesis through stabilization of beta-catenin protein in porcine preadipocytes.
Bovine herpesvirus 1 transiently increased beta-catenin protein levels in bovine kidney cells, but not in rabbit skin cells.
These results demonstrate that activation of AKT (show AKT1 ELISA Kits) is required for gonadotropin regulation of CTNNB1 accumulation and subsequent ovarian E2 production.
beta-catenin, a transcription factor activated by the canonical Wnt signaling pathway, was frequently detected in bovine herpesvirus 1 ORF2-positive trigeminal ganglionic neurons of latently infected, but not mock-infected, calves.
These data demonstrate for the first time that FSH (show BRD2 ELISA Kits) regulates CTNNB1 protein and WNT2 (show WNT2 ELISA Kits) mRNA expressions in bovine granulosa cells, suggesting a potential role of canonical WNT (show WNT2 ELISA Kits) signaling in ovarian steroidogenesis and follicular growth of cattle.
These data provide evidence that testosterone increases cellular beta-catenin content which promotes the expression of beta-catenin-targeted genes and myogenesis in the muscle-derived stem cells of cattle.
that beta-catenin is a plasma membrane-associated protein (show PDZK1IP1 ELISA Kits) in airway smooth muscle that regulates active tension development, presumably by stabilizing cell-cell contacts and thereby supporting force transmission between neighboring cells.
This study demonstrated a relationship between the timing of the development of in vitro-produced bovine embryos and the distribution and localization of the junction protein beta-catenin.
TGF-beta3 (show TGFB3 ELISA Kits) induces the chondrogenic differentiation of pericytes by inducing Wnt (show WNT2 ELISA Kits)/beta-catenin signaling and T-cell factor-induced gene transcription.
cAMP/PKA regulation of GSK3beta (show GSK3b ELISA Kits)/beta-catenin signaling contributes to the increase in progesterone production in corpus luteum.
Palmatin effect on osteoarthritis is likely mediated via the Wnt (show WNT2 ELISA Kits)/beta-catenin and Hedgehog (show SHH ELISA Kits) signaling
These results collectively showed that 2-Deoxy-D-glucose regulates dedifferentiation via beta-catenin pathway in rabbit articular chondrocytes.
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
catenin beta 1 subunit
, catenin beta-1
, beta catenin 1
, catenin (cadherin-associated protein), beta 1, 88kDa
, catenin beta-1-like
, catenin (cadherin associated protein), beta 1, 88kDa
, catenin beta
, beta catenin