Browse our FRZB Proteins (FRZB)

Full name:
Frizzled-Related Protein Proteins (FRZB)
On are 11 Frizzled-Related Protein (FRZB) Proteins from 5 different suppliers available. Additionally we are shipping FRZB Antibodies (56) and FRZB Kits (26) and many more products for this protein. A total of 99 FRZB products are currently listed.
FRE, frezzled, FRITZ, Frp, FRP-3, Frzb-1, FRZB-PEN, FRZB1, FZRB, hFIZ, OS1, SFRP3, SRFP3
list all proteins Gene Name GeneID UniProt
FRZB 20378 P97401
Rat FRZB FRZB 295691  
FRZB 2487 Q92765

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FRZB Proteins (FRZB) by Origin

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Top referenced FRZB Proteins

  1. Human FRZB Protein expressed in Escherichia coli (E. coli) - ABIN1098735 : Baker-Lepain, Lynch, Parimi, McCulloch, Nevitt, Corr, Lane: Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis. in Arthritis and rheumatism 2012 (PubMed)
    Show all 2 references for 1098735

More Proteins for FRZB Interaction Partners

Mouse (Murine) Frizzled-Related Protein (FRZB) interaction partners

  1. Stable overexpression of Frzb in MC3T3-E1 cells increased calcium deposition and osteoblast markers compared with control. Western blot analysis showed that the increased osteogenesis was associated with reduced canonical, but increased non-canonical Wnt (show WNT2 Proteins) signaling.

  2. an inverse septal-to-temporal increase in the expression of sfrp3 that emerges during postnatal development, is reported.

  3. The spatiotemporally dynamic expression ofsFRP3 strongly suggests that sFRP3 has potential functions in the sensory neuron genesis and sensory circuitry formation.

  4. Our results suggest that FrzB may have a protective role on cartilage degradation and matrix metalloproteinase (show MMP20 Proteins) induction in mouse chondrocytes

  5. left ventricles from post-MI mice showed an increased sFRP3 mRNA level, particularly in cardiac fibroblasts, and (iv) mechanical stretch enhanced sFRP3 expression and release in myocardial fibroblasts

  6. Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice.

  7. Study identifies sFRP3 as an inhibitory niche factor from local mature dentate granule neurons that regulates multiple phases of adult hippocampal neurogenesis.

  8. Data indicate an important role for frizzled-related protein (Frzb) in joint homeostasis and highlight the complex biology of WNT (show WNT2 Proteins) signaling in the joint.

  9. Secreted Frizzled-related proteins (sFrps) are expressed in the postnatal cerebral cortex in regional and lamina patterns in the major subdivisions of the cerebral cortex: the olfactory bulb, the hippocampal formation, and the neocortex.

  10. sFRP3 may stimulate differentiation through a beta (show SUCLA2 Proteins)-catenin (show CTNNB1 Proteins)-independent pathway in addition to its previously known function as a decoy receptor for Wnt's

Human Frizzled-Related Protein (FRZB) interaction partners

  1. this study shows that sFRP3 regulates fibroblast-like synociocyte transformation

  2. This may suggest that SFRP3 acts as an agonist of Wnt (show WNT2 Proteins) signaling and promotes invasive behavior.

  3. The secreted frizzled-related protein (show SFRP2 Proteins) and disheveled protein family members appear to be actively involved in the pathogenesis of primary testicular germ cell tumors.

  4. FRZB expression was up-regulated in hepatocellular carcinoma bone metastasis tissue, which suggested that FRZB might play a key role in the HCC (show FAM126A Proteins) bone metastasis.

  5. Positive expression of FRZB was statistically significantly associated with poor prognosis of patients with colon carcinoma hepatic metastasis.

  6. Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3 (show PAX3 Proteins)-FOXO1 (show FOXO1 Proteins)-Positive Alveolar Rhabdomyosarcoma

  7. Intermediate SFRP3 levels are associated with better survival and fewer cardiovascular events than low or high SFRP3 levels, independently of conventional risk factors, in older patients with chronic systolic Heart Failure of ischemic origin.

  8. Intermediate levels of sFRP3 were a predictor of all-cause mortality and re-hospitalization in acute coronary syndromes.

  9. Data suggest secreted FRP3 (frizzled related protein-3 (show HSPB3 Proteins)) interacts with ADAM17 (show ADAM17 Proteins) (A disintegrin/metalloprotease (show ADAM8 Proteins) 17) substrate IL6R (interleukin-6 receptor (show IL6R Proteins)) release; this interaction is down-regulated in osteoarthritis due to rare double variant in FRP3 (show FOLR2 Proteins).

  10. study indicates that increased expression of both SFRP1 (show SFRP1 Proteins) and SFRP3 may contribute to the pathogenesis of IUGR placental dysfunction, whereas the loss of these proteins may be involved in the development of human trophoblastic tumors.

FRZB Protein Profile

Protein Summary

The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.

Alternative names and synonyms associated with FRZB

  • frizzled-related protein (Frzb)
  • frizzled-related protein (FRZB)
  • FRE protein
  • frezzled protein
  • FRITZ protein
  • Frp protein
  • FRP-3 protein
  • Frzb-1 protein
  • FRZB-PEN protein
  • FRZB1 protein
  • FZRB protein
  • hFIZ protein
  • OS1 protein
  • SFRP3 protein
  • SRFP3 protein

Protein level used designations for FRZB

frizzled-related protein 1 , sFRP-3 , secreted frizzled-related protein 3 , secreted frizzled-related sequence protein 3 , frezzled , frizzled homolog-related , frzB-1

20378 Mus musculus
295691 Rattus norvegicus
2487 Homo sapiens
281170 Bos taurus
395545 Gallus gallus
101118419 Ovis aries
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