Browse our FZD8 Proteins (FZD8)

Full name:
Frizzled Family Receptor 8 Proteins (FZD8)
On are 5 Frizzled Family Receptor 8 (FZD8) Proteins from 2 different suppliers available. Additionally we are shipping FZD8 Antibodies (67) and FZD8 Kits (10) and many more products for this protein. A total of 87 FZD8 products are currently listed.
cFz-8, frizzled-8, frizzled8, Fz-8, Fz8, fzd8, hFZ8, Xfz8
list all proteins Gene Name GeneID UniProt
FZD8 8325 Q9H461
Rat FZD8 FZD8 364754 Q498S8
FZD8 14370 Q61091

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FZD8 Proteins (FZD8) by Origin

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More Proteins for FZD8 Interaction Partners

Xenopus laevis Frizzled Family Receptor 8 (FZD8) interaction partners

  1. Xfz8 is involved in the process of normal epithelium formation in the developing pronephric duct and tubules after specific

Chimpanzee Frizzled Family Receptor 8 (FZD8) interaction partners

  1. Human-chimpanzee differences in a FZD8 enhancer (HARE5) alter cell-cycle dynamics in the developing ne (show WNT2 Proteins)ocortex.

Human Frizzled Family Receptor 8 (FZD8) interaction partners

  1. these findings suggest that miR (show MLXIP Proteins)-100 suppresses the migration and invasion of breast cancer cells by targeting FZD-8 and inhibiting Wnt/b-catenin signaling pathway and manipulation of miR (show MLXIP Proteins)-100 may provide a promoting therapeutic strategy for cancer breast treatment.

  2. Frizzled-8 has an important pro-inflammatory role and suggest that its expression is related to chronic bronchitis.

  3. report the discovery of a human-accelerated regulatory enhancer (HARE5) of FZD8, a receptor of the Wnt (show WNT2 Proteins) pathway implicated in brain development and size

  4. Study concludes that expression of Fzd8 is repressed in multiple cancers and suggest it may have a role as a tumor suppressor.

  5. c-Met upregulated FZD8 through the ERK/c-Fos cascade in HN-CSC. Taken together, our results offer a preclinical proof-of-concept for targeting the c-Met/FZD8 signaling axis as a CSC-directed therapy to improve HNSCC treatment

  6. We demonstrated an activation of Wnt-2 (show WNT2 Proteins) signaling via the Frizzled-8 receptor in non-small cell lung cancer cells

  7. These observations suggest that c-Jun is involved in APF-mediated inhibition for bladder tumor cell growth

  8. APF has been shown to be a nine-residue frizzled-8 protein-related sialoglycopeptide. Subsequent research has gradually clarified the molecular mechanisms underlying the profound antiproliferative effect of APF.

  9. Soluble FZC18 and Wnt3a (show WNT3A Proteins) physically interact in a cell-free system and soluble FZC18 binds the frizzled 1 (show Fzd1 Proteins) and 8 receptors.

  10. analysis of the frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt (show WNT2 Proteins) and Dkk1 (show DKK1 Proteins) binding sites on LRP6 (show LRP6 Proteins)

Mouse (Murine) Frizzled Family Receptor 8 (FZD8) interaction partners

  1. Increasing amounts of soluble Frizzled8-cysteine-rich-domain protein modulated Wnt3a (show WNT3A Proteins) signaling in a biphasic manner.

  2. Fzd8 and beta-catenin (show CTNNB1 Proteins) negatively regulate osteoclast differentiation independent of osteoblasts.

  3. Study shows Flamingo (Fmi) and Frizzled (Fz) 8, members of noncanonical Wnt signaling, both express in and functionally maintain quiescent long-term hematopoietic stem cells.

  4. study presents the structure of Xenopus Wnt8 (XWnt8 (show WNT8A Proteins)) in complex with the mouse Fz8-cysteine-rich domain to a resolution of 3.25 A

  5. studies suggest a dose-dependent regulation of signaling by Fz5 and Fz8 in optic fissure/disc formation and progenitor expansion

  6. A major role for frizzled 4 (show FZD4 Proteins) and frizzled 8 in controlling ureteric growth in the developing kidney.

  7. analysis of the frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt (show WNT2 Proteins) and Dkk1 (show DKK1 Proteins) binding sites on LRP6 (show LRP6 Proteins)

  8. Several lines of evidence that the mouse Cristin/R-spondin family proteins function as Fzd8 and LRP6 (show LRP6 Proteins) receptor ligands and induce the canonical Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway, leading to TCF (show HNF4A Proteins)-dependent gene activation, are presented.

  9. Molecular modeling of the complex between the xWNT8 (show WNT8A Proteins) protein and the CRD (show CRX Proteins) domain of mFZD8

  10. Insulin-like growth-factor-binding protein-4 (show IGFBP4 Proteins) physically interacted with a Wnt receptor, Frizzled 8 (Frz8), and a Wnt (show WNT2 Proteins) co-receptor, low-density lipoprotein receptor-related protein 6 (LRP6 (show LRP6 Proteins)), and inhibited the binding of Wnt3A (show WNT3A Proteins) to Frz8 and LRP6 (show LRP6 Proteins)

FZD8 Protein Profile

Protein Summary

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This gene is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Alternative names and synonyms associated with FZD8

  • frizzled family receptor 5 (FZD5)
  • frizzled family receptor 8 (fzd8-b)
  • frizzled family receptor 8 (FZD8)
  • frizzled family receptor 8 (fzd8)
  • frizzled family receptor 8 (Fzd8)
  • frizzled family receptor 8 (fzd8-a)
  • frizzled homolog 8 (Drosophila) (Fzd8)
  • frizzled homolog 8 (Drosophila) (FZD8)
  • cFz-8 protein
  • frizzled-8 protein
  • frizzled8 protein
  • Fz-8 protein
  • Fz8 protein
  • fzd8 protein
  • hFZ8 protein
  • Xfz8 protein

Protein level used designations for FZD8

frizzled-8 , frizzled 8 , frizzled homolog 8 , frizzled 8, seven transmembrane spanning receptor , fz-8 , frizzled 8 protein

395571 Gallus gallus
399367 Xenopus laevis
466040 Pan troglodytes
100038274 Xenopus (Silurana) tropicalis
8325 Homo sapiens
364754 Rattus norvegicus
616913 Bos taurus
373690 Xenopus laevis
14370 Mus musculus
374059 Gallus gallus
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