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Browse our anti-GPBAR1 (GPBAR1) Antibodies

Full name:
anti-G Protein-Coupled Bile Acid Receptor 1 Antibodies (GPBAR1)
On are 111 G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) Antibodies from 13 different suppliers available. Additionally we are shipping GPBAR1 Kits (6) and GPBAR1 Proteins (3) and many more products for this protein. A total of 126 GPBAR1 products are currently listed.
BG37, CD344, EVR1, FEVR, Fz-4, Fz4, FZD4S, FzE4, Gpbar1, GPCR, GPCR19, GPR131, hFz4, M-BAR, MGC84403, Tgr5
list all antibodies Gene Name GeneID UniProt
GPBAR1 8322 Q9ULV1
GPBAR1 227289 Q80SS6
GPBAR1 338443 Q80T02

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anti-Human GPBAR1 Antibodies:

anti-Mouse (Murine) GPBAR1 Antibodies:

anti-Rat (Rattus) GPBAR1 Antibodies:

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More Antibodies against GPBAR1 Interaction Partners

Human G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) interaction partners

  1. bile acids promote intestinal epithelial cell proliferation and decrease mucosal injury by upregulating TGR5 expression in obstructive jaundice.

  2. The generated contour maps revealed the important structural insights for the activity of the compounds. The results obtained from this study could be helpful in the development of novel and more potent agonists of TGR5.

  3. human FZD4 assembles-in a DVL-independent manner-with Galpha12/13 but not representatives of other heterotrimeric G protein subfamilies.

  4. TGR5 functions as a tumor-suppressor in patients with ampullary adenocarcinoma and preoperative hyperbilirubinemia

  5. We conclude that Claudin-2 (show CLDN2 Antibodies) expression is significantly associated with bile acid receptors VDR (show CYP27B1 Antibodies) and TGR5 expression. Our studies identify a novel role of a tight junction protein (show OCLN Antibodies) in the development and progression of esophageal mucosal metaplasia, dysplasia and carcinoma.

  6. Several novel mutations (missense, non-stop (show USP22 Antibodies) and insertion) were detected in the coding regions of FZD4 (show FZD4 Antibodies), TSPAN12 (show TSPAN12 Antibodies) and ZNF408 (show ZNF408 Antibodies) genes among the unrelated familial exudative vitreoretinopathy probands. The mutations in FZD4 (show FZD4 Antibodies) and TSPAN12 (show TSPAN12 Antibodies) were involved in autosomal dominant and autosomal recessive families and further validates the involvement of these gene in exudative vitreoretinopathy development.

  7. this is the first report of bile acid derivatives able to antagonize GPBAR1 and and farnesoid X receptor (show xpr1 Antibodies) (FXR (show NR1H4 Antibodies)) modulatory activity.

  8. Two were novel mutations: p.E134* and p.T503fs of FZD4 (show FZD4 Antibodies) lead to the loss of FZD4 (show FZD4 Antibodies) activity.

  9. Letter: FZD4 (show FZD4 Antibodies)+ and FZD4 (show FZD4 Antibodies)- melanocytes were significantly lower in hair follicles of patients with rhododenol-induced leukoderma.

  10. These findings identify TGR5 as a suppressor of gastric cancer cell proliferation and migration

Mouse (Murine) G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) interaction partners

  1. The results suggest that TGR5 activation mediates cross-talk between alpha- and beta-cells by switching from glucagon (show GCG Antibodies) to GLP-1 (show GCG Antibodies) to restore beta- cell mass and function under hyperglycemic conditions.

  2. TGR5 is an important mediator of bile acid-induced cholangiocyte proliferation in vivo and in vitro. Furthermore, TGR5 protects cholangiocytes from death receptor-mediated apoptosis.

  3. miR (show MLXIP Antibodies)-26a is a target gene of bile acid receptor (show NR1H4 Antibodies) GPBAR-1/TGR5

  4. Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling

  5. Data show that the action of bile acids on -like peptide-1 (GLP-1 (show GCG Antibodies)) secretion is predominantly mediated by G protein-coupled bile acid receptor (show NR1H4 Antibodies) GPBAR1 (TGR5) located on the basolateral L-cell membrane.

  6. TGR5 appears to be crucial for protecting the regenerating liver from bile acid overload.

  7. Activation of TGR5 alleviates neuroinflammation and improves outcome in hepatic encephalopathy.

  8. XGB (show GTPBP4 Antibodies) increases BMR by TGR5-dependent mechanisms in mice

  9. GPBAR1 plays a role in secondary bile acid induced vasodilation via reglation of cystathionine gamma-lyase. The GPBAR1/CSE pathway might contribute to endothelial dysfunction and hyperdynamic circulation in liver cirrhosis.

  10. these studies reveal a signaling pathway downstream of TGR5 that modulates chemokine (show CCL1 Antibodies) expression in response to high-fat diet

Cow (Bovine) G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) interaction partners

  1. TGR5 agonism induces NO production via Akt (show AKT1 Antibodies) activation and intracellular Ca(2 (show CA2 Antibodies)+) increase in vascular endothelial cells, and this function inhibits monocyte adhesion in response to inflammatory stimuli.

Rabbit G Protein-Coupled Bile Acid Receptor 1 (GPBAR1) interaction partners

  1. TGR5 has been linked to signaling pathways involved in metabolism, cell survival, proliferation and apoptosis, which suggest a possible role of TGR5 in cancer development.

GPBAR1 Antigen Profile

Antigen Summary

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Alternative names and synonyms associated with GPBAR1

  • G protein-coupled bile acid receptor 1 (gpbar1) antibody
  • G protein-coupled bile acid receptor 1 (GPBAR1) antibody
  • frizzled family receptor 4 (FZD4) antibody
  • G protein-coupled bile acid receptor 1 (Gpbar1) antibody
  • G protein-coupled receptor (TGR5) antibody
  • BG37 antibody
  • CD344 antibody
  • EVR1 antibody
  • FEVR antibody
  • Fz-4 antibody
  • Fz4 antibody
  • FZD4S antibody
  • FzE4 antibody
  • Gpbar1 antibody
  • GPCR antibody
  • GPCR19 antibody
  • GPR131 antibody
  • hFz4 antibody
  • M-BAR antibody
  • MGC84403 antibody
  • Tgr5 antibody

Protein level used designations for GPBAR1

G protein-coupled bile acid receptor 1 , G-protein coupled bile acid receptor BG37 , WNT receptor frizzled-4 , frizzled 4, seven transmembrane spanning receptor , frizzled homolog 4 , frizzled-4 , G-protein coupled bile acid receptor 1 , G-protein coupled receptor GPCR19 , hBG37 , hGPCR19 , membrane bile acid receptor , membrane-type receptor for bile acids , G protein-coupled receptor TGR5 , G protein-coupled receptor , M-BAR

447779 Xenopus laevis
488521 Canis lupus familiaris
697937 Macaca mulatta
741111 Pan troglodytes
8322 Homo sapiens
151306 Homo sapiens
227289 Mus musculus
338443 Rattus norvegicus
317756 Bos taurus
100009346 Oryctolagus cuniculus
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