Browse our anti-WIF1 (WIF1) Antibodies

Full name:
anti-WNT Inhibitory Factor 1 Antibodies (WIF1)
On are 142 WNT Inhibitory Factor 1 (WIF1) Antibodies from 19 different suppliers available. Additionally we are shipping WIF1 Kits (20) and WIF1 Proteins (18) and many more products for this protein. A total of 187 WIF1 products are currently listed.
AW107799, GB10372, shf, WIF-1, WIF1, zgc:110507

Most Popular Reactivities for anti-WIF1 (WIF1) Antibodies

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anti-Human WIF1 Antibodies:

anti-Mouse (Murine) WIF1 Antibodies:

anti-Rat (Rattus) WIF1 Antibodies:

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Top referenced anti-WIF1 Antibodies

  1. Human Monoclonal WIF1 Primary Antibody for IF, IHC - ABIN967258 : Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer. in BMC cancer 2009 (PubMed)
    Show all 3 references for 967258

  2. Human Polyclonal WIF1 Primary Antibody for IHC (p), WB - ABIN389184 : Elston, Gill, Conaglen, Clarkson, Shaw, Law, Cook, Little, Clifton-Bligh, Robinson, McDonald: Wnt pathway inhibitors are strongly down-regulated in pituitary tumors. in Endocrinology 2008 (PubMed)
    Show all 3 references for 389184

  3. Human Monoclonal WIF1 Primary Antibody for ICC, IHC - ABIN969457 : Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: Functional significance of Wnt inhibitory factor-1 gene in kidney cancer. in Cancer research 2009 (PubMed)
    Show all 2 references for 969457

  4. Human Polyclonal WIF1 Primary Antibody for WB - ABIN658480 : Licchesi, Van Neste, Tiwari, Cope, Lin, Baylin, Herman: Transcriptional regulation of Wnt inhibitory factor-1 by Miz-1/c-Myc. in Oncogene 2010 (PubMed)
    Show all 2 references for 658480

  5. Human Polyclonal WIF1 Primary Antibody for IHC (p), WB - ABIN389185 : Chan, Cui, van Hasselt, Li, Srivastava, Jin, Ng, Wang, Lee, Tsao, Zhong, Robertson, Rha, Chan, Tao: The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas. in Laboratory investigation; a journal of technical methods and pathology 2007 (PubMed)
    Show all 2 references for 389185

More Antibodies against WIF1 Interaction Partners

Human WNT Inhibitory Factor 1 (WIF1) interaction partners

  1. Our data suggests that total cellular b-catenin levels decrease in the presence of secreted frizzled-related protein 1 (show SFRP1 Antibodies) and Wnt inhibitory factor 1, and a significant increase in cell death after tyrosine kinase (show TXK Antibodies) inhibitor treatment is observed. On the contrary, when secreted frizzled-related protein 1 (show SFRP1 Antibodies) is suppressed, total b-catenin levels increase in the cell and the cells become resistant to tyrosine kinase (show TXK Antibodies) inhibitors.

  2. Gallbladder cancer patients with hypermethylated WIF-1 exhibited worse overall survival than those with hypomethylated WIF-1.

  3. In astrocytoma specimens, tumor areas with numerous single cells were identified which strongly express Wif-1.

  4. Hypermethylation of WIF1 (WNT inhibitory factor 1) and NPY (neuropeptide Y (show NPY Antibodies)) genes was significantly higher in tumor tissue compared to normal tissue, independently of tumor stage.

  5. the expression levels of WIF-1 were low in gallbladder cancer tumor tissues and the GBC-SD, SGC (show SGCB Antibodies)-996 and NOZ gallbladder cancer cell lines. This low expression was associated with the methylation status of the WIF-1 gene promotor.

  6. Compared with adjacent normal tissues, the methylation frequencies of WIF-1, RASSF1A (show RASSF1 Antibodies), and CDH13 (show CDH13 Antibodies) genes were significantly higher but the mRNA levels of these 3 genes were significantly lower in EC tissues. The survival rates of patients with WIF-1, RASSF1A (show RASSF1 Antibodies), and CDH13 (show CDH13 Antibodies) methylations were significantly lower than those of patients without methylation

  7. Promoter hypermethylation WIF1 play an important role in the carcinogenesis of lung cancer.

  8. HOTAIR can affect the radiosensitivity of pancreatic ductal adenocarcinoma (PDAC) cells partly via regulating the expression of WIF-1, and HOTAIR-WIF-1 axis is a potential target for PDAC radiotherapy.

  9. beta-catenin (show CTNNB1 Antibodies) expression may also be a poor prognostic factor for cervical cancer (CC) while WIF1 could be a potential drug target for treatment of advanced CC.

  10. Reduced expression of Wif-1 and increased expression of beta-catenin (show CTNNB1 Antibodies) may be involved in the pathogenesis of childhood acute lymphoblastic leukemia (ALL).

Mouse (Murine) WNT Inhibitory Factor 1 (WIF1) interaction partners

  1. Wif1 localizes to the enamel knot (show KCNK7 Antibodies) in which Wif1 regulates apoptosis by mediating and regulating Wnt (show WNT2 Antibodies)-beta-catenin (show CTNNB1 Antibodies) signaling. Thus, Wif1 plays an essential role in tooth development.

  2. WIF1 has a role in breast neoplasms: its inhibition significantly relieves the cancer stem cell-limiting effects of dietary compound isoliquiritigenin

  3. results demonstrate that Wif1 is not targeted for silencing by DNA methylation (show HELLS Antibodies) in OS. Instead, the reduced expression of Wif1 in OS cells is in context with their stage in differentiation

  4. EZH2 (show EZH2 Antibodies)-induced downregulation of WIF1 expression may partially regulate Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)-dependent crypt hyperplasia in response to citrobacter rodentium infection

  5. Dysregulation of this endodermal Shh-Wif1-b-catenin signaling axis contributes to ARM pathogenesis.

  6. It is anticipated that our findings will contribute to expansion of our understanding of WIF1 biological function on heart development and possible modes of treatment of heart diseases

  7. WIF1 secretion by the Mullerian duct mesenchyme plays a role in Mullerian duct regression in fetal males

  8. These data suggest that WIF-1 may take part in the fine-tuning of cartilage and bone turnover, promoting the balance of cartilage versus bone anabolism.

  9. Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development

  10. Osteoblastic Wif1 overexpression disrupts stem cell quiescence, leading to a loss of self-renewal potential.

Xenopus laevis WNT Inhibitory Factor 1 (WIF1) interaction partners

  1. In an examination of signaling pathways in developing Xenopus lung, wif1 was expressed in the mesenchyme layer of the entire lungs through stages 39-41.

Zebrafish WNT Inhibitory Factor 1 (WIF1) interaction partners

  1. Data describe the importance of proper level of Wnt (show WNT2 Antibodies) signaling for normal development of swimbladder in Wif1 morphant zebrafish.

WIF1 Antigen Profile

Antigen Summary

The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.

Alternative names and synonyms associated with WIF1

  • WNT inhibitory factor 1 (WIF-1) antibody
  • wnt inhibitory factor 1 (CpipJ_CPIJ003761) antibody
  • WNT inhibitory factor 1 (wif1) antibody
  • WNT inhibitory factor 1 (WIF1) antibody
  • Wnt inhibitory factor 1 (Wif1) antibody
  • wnt inhibitory factor 1 (wif1) antibody
  • AW107799 antibody
  • GB10372 antibody
  • shf antibody
  • WIF-1 antibody
  • WIF1 antibody
  • zgc:110507 antibody

Protein level used designations for WIF1

shifted , wnt inhibitory factor 1 , WNT inhibitory factor 1 , wnt inhibitory factor 1-like , Wnt inhibitory factor-1 , WIF-1 , wnt inhibitory factor-1

552805 Apis mellifera
6035098 Culex quinquefasciatus
100127197 Xenopus (Silurana) tropicalis
100484613 Ailuropoda melanoleuca
467056 Pan troglodytes
11197 Homo sapiens
24117 Mus musculus
417831 Gallus gallus
481148 Canis lupus familiaris
100511326 Sus scrofa
533672 Bos taurus
114557 Rattus norvegicus
399375 Xenopus laevis
30476 Danio rerio
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