WIF1 antibody (C-Term)

Catalog No. ABIN389185

This Rabbit Polyclonal antibody specifically detects WIF1 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.It has been mentioned in 1 publication

Quick Overview for WIF1 antibody (C-Term) (ABIN389185)

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WIF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB10584

Product Details anti-WIF1 Antibody

Binding Specificity: AA 347-376, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WIF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 347-376 amino acids from the C-terminal region of human WIF1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-WIF1 antibody (ABIN389185)

Zhu, Yang, Liu, Zou, Yuan, Hu et al.: "Association between Wnt inhibitory factor 1 and receptor tyrosine kinase-like orphan receptor 2 protein expression and the clinical pathological significance in benign and malignant pancreatic ..." in: Oncology letters, Vol. 13, Issue 4, pp. 2244-2252, (2017) (PubMed).

Target Details for WIF1

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Alternative Name: WIF1

Background: WNT proteins are extracellular signaling molecules involved in the control of embryonic development. WIF1 is a secreted protein, which binds WNT proteins and inhibits their activities. This protein contains a WNT inhibitory factor (WIF) domain and 5 epidermal growth factor (EGF)-like domains. It may be involved in mesoderm segmentation. This protein is found to be present in fish, amphibia and mammals.

Molecular Weight: 41528

Gene ID: 11197

NCBI Accession: NP_009122

UniProt: Q9Y5W5

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation