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Browse our WNT5A Proteins (WNT5A)

Full name:
Wingless-Type MMTV Integration Site Family, Member 5A Proteins (WNT5A)
On are 13 Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) Proteins from 6 different suppliers available. Additionally we are shipping WNT5A Antibodies (99) and WNT5A Kits (19) and many more products for this protein. A total of 137 WNT5A products are currently listed.
8030457G12Rik, hWNT5A, wnt-5A, WNT5A, wnt5a-B
list all proteins Gene Name GeneID UniProt
WNT5A 22418 P22725
WNT5A 7474 P41221
WNT5A 64566 Q9QXQ7

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WNT5A Proteins (WNT5A) by Origin

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Top referenced WNT5A Proteins

  1. Human WNT5A Protein expressed in Wheat germ - ABIN1325364 : Bazhin, Tambor, Dikov, Philippov, Schadendorf, Eichmüller: cGMP-phosphodiesterase 6, transducin and Wnt5a/Frizzled-2-signaling control cGMP and Ca(2+) homeostasis in melanoma cells. in Cellular and molecular life sciences : CMLS 2010 (PubMed)

More Proteins for WNT5A Interaction Partners

Zebrafish Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. There is an important role of Wnt5a in kidney development. Disrupted Wnt5a results in kidney cysts in zebrafish and pleiotropic abnormal kidney development in mice.

  2. Wnt5a acts as a chemoattractant in the emerging limb bud where it contributes to the establishment of cell polarity that is likely to underlie the oriented cell behaviours

Mouse (Murine) Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. Decreased expressions of Wnt1 (show WNT1 Proteins) and Wnt5a.

  2. indicate that restricted expression of Wnt5a in the caudal SpM (show NPC1 Proteins) is essential for normal OFT morphogenesis, and uncover a novel function of spatially regulated cell cohesion by Wnt5a in driving the deployment of SHF (show SHF Proteins) cells from the SpM (show NPC1 Proteins) into the OFT

  3. Findings indicate wingless-related MMTV integration site 5A protein (WNT5a) as a key regulator of follicle development and gonadotropin responsiveness.

  4. The oxidative stress of diabetes mellitus impairs Wnt (show WNT2 Proteins) signaling and causes cardiac outlet defects that are rescued by SOD1 (show SOD1 Proteins) overexpression

  5. The results in a potent increase in odontoblastic cell differentiation, indicating the unique involvement of Atg5 (show ATG5 Proteins), autophagy and Wnt5 signaling in CS/BMP-4 (show BMP4 Proteins)-induced differentiation of ES cells into odontoblast-like cells, at a relatively early stage.

  6. the Wnt5a/Frizzled-2 (show FZD2 Proteins) axis suppresses beta-catenin (show CTNNB1 Proteins) signaling in hepatocytes in an autocrine manner, thereby contributing to timely conclusion of the liver regeneration process

  7. effects on hypoxic pulmonary hypertension by regulating pulmonary vascular remodeling and right ventricular hypertrophy via reduction in beta-catenin (show CTNNB1 Proteins)/cyclin D1 (show CCND1 Proteins) signaling

  8. Wnt5a regulates the pathogenesis of gp120 (show ITIH4 Proteins)-induced pain.

  9. Study identified a novel Wnt5a/Fzd4 (show FZD4 Proteins) signaling pathway that contributes to the regulation of dendrite morphogenesis

  10. The Wnt5a-Ror2 (show ROR2 Proteins) axis promotes the signaling circuit between interleukin-12 and interferon-gamma (show IFNG Proteins) in colitis

Xenopus laevis Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. Xenopus adult stem cells originate from the larval absorptive cells expressing Ror2 (show ROR2 Proteins), which require Wnt5a/Ror2 (show ROR2 Proteins) signaling for their dedifferentiation accompanied by changes in cell morphology.

  2. Data show that PAPC (show PCDH8 Proteins) signaling via RhoA (show RHOA Proteins) and Wnt5a/Ror2 (show ROR2 Proteins) activity are required to keep cells aligned in apical-basal orientation during invagination of the ear placode.

  3. Data show that Rspo3 (show RSPO3 Proteins) binds syndecan 4 and that together they activate Wnt5a/PCP (show PRCP Proteins) signaling.

  4. In an examination of signaling pathways in developing Xenopus lung, wnt5a was expressed in the mesenchyme layer of the entire lungs through stages 39-41.

  5. Wnt5a reduces cell surface levels and promotes ubiquitination and degradation of SDC4 (show SDC4 Proteins) in dorsal mesodermal cells from Xenopus gastrulae.

  6. Transcriptional regulation of XPAPC (show PCDH8 Proteins) by XWnt-5A requires the receptor tyrosine kinase Ror2 (show ROR2 Proteins).

  7. Xwnt-5a plays an instructive role in larval tail regeneration via Wnt (show WNT2 Proteins)/JNK (show MAPK8 Proteins) signaling

Human Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. Wnt5a is increased and beta-catenin (show CTNNB1 Proteins) is decreased in parenchyma from idiopathic pulmonary fibrosis patients.

  2. results corroborated previous findings of Ryk (show RYK Proteins)-mediated Wnt5a effect, and suggested a role for Ror2 (show ROR2 Proteins) in the Wnt5a machinery in glioblastoma

  3. WNT5A participates in the biology of odontogenic tumors and inflammatory cyst but not in developmental cyst.

  4. Mutation in WNT5A may serve as a susceptibility factor for Congenital Anomalies Of Kidney And Urinary Tract.

  5. Wnt5a-Ror2 (show ROR2 Proteins) signaling enhances expression and secretion of CXCL16 (show CXCL16 Proteins) in mesenchymal stem cells thereby activating CXCR6 (show CXCR6 Proteins) expressed on tumor cells to promote proliferation.

  6. The homozygous genotypes (CC for rs524153 and GG for rs504849) were associated with a lower WNT5A transcriptional level compared with the transcriptional level of those with wild-type genotypes.

  7. Epigenetic inactivation of the WNT5A promoter B involves both DNA methylation (show HELLS Proteins) and histone modifications. Differential expression of the WNT5A alternative promoters A and B is a characteristic of osteosarcomas.

  8. Findings suggest that high receptor tyrosine kinase (show RET Proteins)-like orphan receptor (show NR1D2 Proteins) (ROR) 2 (show ROR2 Proteins) or proto-oncogene (show RAB1A Proteins) protein Wnt-5A (Wnt5a) expression is associated with poor prognosis in non-small cell lung cancer (NSCLC).

  9. Noncanonical Wnt5a signaling and JNK (show MAPK8 Proteins) activity contribute to vascular insulin (show INS Proteins) resistance and endothelial dysfunction.

  10. This study identifies an interaction between ROR1 (show ROR1 Proteins) and ROR2 (show ROR2 Proteins) that is required for Wnt5a signaling that promotes leukemia chemotaxis and proliferation.

Cow (Bovine) Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. WNT5A is a negative regulator of FSH (show BRD2 Proteins)-stimulated granulosa cell steroidogenesis in cattle.

Rabbit Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) interaction partners

  1. Wnt-5A may be associated with cartilage destruction by promoting the expression of matrix metalloproteinases.

WNT5A Protein Profile

Protein Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with WNT5A

  • wingless-type MMTV integration site family, member 5A (WNT5A)
  • wingless-type MMTV integration site family, member 5a (wnt5a)
  • Wnt signaling ligand (wnt5)
  • wingless-related MMTV integration site 5A (Wnt5a)
  • wingless-type MMTV integration site family, member 5A (wnt5a)
  • wingless-type MMTV integration site family, member 5A (Wnt5a)
  • WNT-5A protein (WNT-5A)
  • 8030457G12Rik protein
  • hWNT5A protein
  • wnt-5A protein
  • WNT5A protein
  • wnt5a-B protein

Protein level used designations for WNT5A

wingless-type MMTV integration site family, member 5A , protein Wnt-5a , protein Wnt-5a-like , XWnt-5a , Wnt-5a , WNT-5A protein , Wnt-5a protein , wingless-related MMTV integration site 5A , wingless-type MMTV integration site 5A

484721 Canis lupus familiaris
568191 Danio rerio
705692 Macaca mulatta
100401066 Callithrix jacchus
100447525 Pongo abelii
100012859 Monodelphis domestica
100602014 Nomascus leucogenys
445761 Ciona intestinalis
22418 Mus musculus
378689 Xenopus laevis
395703 Gallus gallus
7474 Homo sapiens
530005 Bos taurus
64566 Rattus norvegicus
100009381 Oryctolagus cuniculus
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