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anti-CD209 Molecule (CD209) Antibodies

CD209 encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. Additionally we are shipping CD209 Molecule Proteins (14) and CD209 Molecule Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CD209 288379  
CD209 30835 Q9NNX6
CD209 170786 Q91ZX1
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Top anti-CD209 Molecule Antibodies at

Showing 10 out of 431 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse FITC FACS Staining of CD209 transfected K562 cells with MOUSE ANTI HUMAN CD209: FITC (ABIN181973) 0.1 mg Log in to see 6 to 8 Days
Human Mouse PE FACS   25 Tests Log in to see 6 to 8 Days
Human Mouse Un-conjugated FACS, IF   0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-CD209 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate WB Suggested Anti-CD209  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated Func, FACS, IF Flow cytometric analysis using anti CD209 antibody ABIN181974 0.5 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, WB Figure 1. DC-SIGN antibody staining of Paraformaldehyde-Fixed HeLa by Immunofluorescence at 1/200 dilution. Figure 2. DC-SIGN antibody staining of HeLa (A) whole cell lysate (30 µg) at 1/5000 dilution, 10% SDS PAGE. 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB Western blot analysis of CD209 Antibody (Center) (ABIN653410) in HL-60 cell line lysates (35 µg/lane). CD209 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days

CD209 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CD209 Molecule Antibodies

  1. Human Polyclonal CD209 Primary Antibody for WB - ABIN871703 : Engering, Geijtenbeek, van Vliet, Wijers, van Liempt, Demaurex, Lanzavecchia, Fransen, Figdor, Piguet, van Kooyk: The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 3 references for ABIN871703

  2. Human Monoclonal CD209 Primary Antibody for FACS - ABIN320225 : Relloso, Puig-Kröger, Pello, Rodríguez-Fernández, de la Rosa, Longo, Navarro, Muñoz-Fernández, Sánchez-Mateos, Corbí: DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 2 references for ABIN320225

  3. Human Monoclonal CD209 Primary Antibody for FACS - ABIN181973 : Melero, Gabari, Corbí, Relloso, Mazzolini, Schmitz, Rodriguez-Calvillo, Tirapu, Camafeita, Albar, Prieto: An anti-ICAM-2 (CD102) monoclonal antibody induces immune-mediated regressions of transplanted ICAM-2-negative colon carcinomas. in Cancer research 2002 (PubMed)
    Show all 2 references for ABIN181973

  4. Human Monoclonal CD209 Primary Antibody for FACS, IF - ABIN1106050 : Khoo, Chan, Chan, Lin: DC-SIGN and L-SIGN: the SIGNs for infection. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)

More Antibodies against CD209 Molecule Interaction Partners

Cow (Bovine) CD209 Molecule (CD209) interaction partners

  1. The development and use of CD209 to characterize the phenotype of CD209 expressing cells in bovine blood using flow cytometry is reported.

  2. a DC-SIGN-like molecule expressed specifically by bovine DC. This molecule may play an important role in the infection of bovine (DC) cells with M. bovis.

Pig (Porcine) CD209 Molecule (CD209) interaction partners

  1. The cloning and characterization of the cDNA and gene encoding porcine DC-SIGN (pDC (show PDC Antibodies)-SIGN)is reported. The results will help better understand the biological role(s) of DC-SIGN family in innate immunity during the evolutionary process.

Zebrafish CD209 Molecule (CD209) interaction partners

  1. identification and functional characterization of DC-SIGN/CD209 molecule in zebrafish

Human CD209 Molecule (CD209) interaction partners

  1. DC-SIGNR (show CLEC4M Antibodies) VNTR and DC-SIGN VNTR, were not associated with the risk of pulmonary tuberculosis in a sample of Iranian population

  2. CD209 gene -871A/G is associated with decreased susceptibility to pulmonary tuberculosis (PT) overall; -336A/G polymorphism is associated with increased susceptibility in Asians and -139G/A polymorphism is not associated with susceptibility to PT

  3. The high-mannose N-linked glycan at N154 of Japanese encephalitis virus E glycoprotein was shown to be crucial for binding to DC-SIGN and subsequent internalization.

  4. Preliminary study suggests that OAS (show SMOC1 Antibodies) gene cluster and CD209 gene polymorphisms influence the risk of developing clinical symptoms in Chikungunya virus-infected patients.

  5. DC-SIGN can promote the maturation and activation of dendritic cells on recognition of hepatitis B virus, but wild type virus can escape recognition by DC-SIGN to a certain extent with the help of demannosylated modification.

  6. Colorectal mucus can bind the C-type lectin (show MBL2 Antibodies) DC-SIGN and block HIV-1 trans-infection of both CCR5 (show CCR5 Antibodies) and CXCR4 (show CXCR4 Antibodies) using HIV-1 strains.

  7. Engagement of sIg (show PICALM Antibodies) in FL cells or normal B cells by anti-Ig led to endocytosis in vitro as expected, but DC-SIGN, even when cross-linked, did not lead to significant endocytosis of sIg (show PICALM Antibodies)

  8. M2 macrophages induced a DC-SIGN-dependent adhesion of highly mannosylated IgM(+) FL B cells and triggered BCR (show BCR Antibodies)-associated kinase activation.

  9. DC-SIGN-induced ISGF3 (show STAT1 Antibodies) by fucose-based PAMPs has an essential role in driving IL-27 (show IL27 Antibodies) and subsequent TFH polarization, which might be harnessed for vaccination design

  10. selective engagement of dendritic cell-SIGN resulting in intracellular persistence in myeloid dendritic cells; however TLR2 (show TLR2 Antibodies) activation can overcome autophagy evasion and pathogen persistence in dendritic cells

Rhesus Monkey CD209 Molecule (CD209) interaction partners

  1. DC-SIGN+ cells showed a clear differential distribution in the decidua in the first 2 weeks of pregnancy, being found only adjacent to the implantation site

  2. DC-SIGN expression in mesenteric lymph nodes is significantly downregulated in simian immunodeficiency virus-infected pig-tailed macaques.

Mouse (Murine) CD209 Molecule (CD209) interaction partners

  1. results suggested that podocytes in lupus nephritis can exert dendritic cell-like function through their expression of DC-SIGN, which may be involved in immune and inflammatory responses of renal tissues

  2. High-resolution crystal structures of the SIGN-R1 carbohydrate recognition domain show 2 binding sites allowing SIGNR1 (show CD209B Antibodies) to simultaneously bind both immune glycoproteins and microbial polysaccharide components.

  3. Data suggest that serum amyloid P (SAP (show APCS Antibodies)) activates CD209 DC-SIGN to regulate the innate immune system differently from C-reactive protein (CRP (show CRP Antibodies)), and that DC-SIGN is a target for antifibrotics.

  4. Intestinal enterocytes regulate tissue-associated immune compartments under the control of DC-SIGN in inflammatory bowel disease.

  5. In vivo T cell activation induces the formation of CD209(+) PDL-2 (show PDCD1LG2 Antibodies)(+) dendritic cells.

  6. CD209a expression on dendritic cells is critical for the development of pathogenic Th17 cell responses in murine schistosomiasis.

  7. CD209a is activated in macrophages by LECT2 (show LECT2 Antibodies).

  8. The neck region of the C-type lectin DC-SIGN regulates its surface spatiotemporal organization and virus-binding capacity on antigen-presenting cells

  9. interactions between the CRD (show CRX Antibodies) of DC-SIGN and the extracellular matrix and/or cis (show CISH Antibodies) interactions with transmembrane scaffolding protein(s) play an essential role in organizing these microdomains

  10. analysis of activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3 (show ICAM3 Antibodies))-grabbing nonintegrin (DC-SIGN), and beta2 integrins

CD209 Molecule (CD209) Antigen Profile

Protein Summary

This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332\; often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.

Gene names and symbols associated with anti-CD209 Molecule (CD209) Antibodies

  • CD209 molecule (CD209) antibody
  • CD209 antigen (Cd209) antibody
  • CD209-like protein (cd209) antibody
  • CD209 molecule (cd209) antibody
  • CD209 (dc-sign) antibody
  • CD209a antigen (Cd209a) antibody
  • CD209c molecule (Cd209c) antibody
  • Cd209 antibody
  • CDSIGN antibody
  • CIRE antibody
  • CLEC4L antibody
  • CLEC4M antibody
  • DC-SIGN antibody
  • DC-SIGN1 antibody
  • Dcsign antibody
  • si:ch211-224h1.3 antibody
  • SIGN-R1 antibody
  • SIGNR5 antibody

Protein level used designations for anti-CD209 Molecule (CD209) Antibodies

CD209 antigen , CD209-like protein , C-type lectin domain family 4, member M , DC-SIGN protein , CD209 , C-type lectin domain family 4 member L , C-type lectin domain family 4, member L , HIV gpl20-binding protein , dendritic cell-specific ICAM-3-grabbing non-integrin 1 , dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin , DC-SIGN1 , dendritic cell-specific ICAM-3 grabbing non-integrin , putative mannose-binding C-type lectin , CD209 antigen-like protein A , dendritic cell-specific ICAM-3-grabbing non-integrin , CD209 antigen-like protein C , CD209c antigen

100460708 Pongo abelii
288379 Rattus norvegicus
100136662 Oncorhynchus mykiss
485000 Canis lupus familiaris
513266 Bos taurus
100170134 Sus scrofa
100334918 Danio rerio
100462978 Felis catus
100529184 Oryzias latipes
30835 Homo sapiens
450160 Pan troglodytes
574211 Macaca mulatta
170786 Mus musculus
688951 Rattus norvegicus
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