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CD44 Proteins (CD44)

The protein encoded by CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. Additionally we are shipping CD44 Antibodies (1129) and CD44 Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD44 12505 P15379
CD44 25406  
CD44 960 P16070
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Top CD44 Proteins at

Showing 10 out of 30 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 59 to 64 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 59 to 64 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days

CD44 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
Rat (Rattus) ,

Human , , , , , , ,
, , , ,

Top referenced CD44 Proteins

  1. Human CD44 Protein expressed in Wheat germ - ABIN1348653 : Gebhard, Jain, Nair, Emmons, Argilagos, Koomen, McLaughlin, Hazlehurst: MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. in Molecular cancer therapeutics 2013 (PubMed)
    Show all 2 references for ABIN1348653

  2. Human CD44 Protein expressed in HEK-293 Cells - ABIN2180798 : Hanley, Burdick, Konstantopoulos, Sackstein: CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. in Cancer research 2005 (PubMed)

More Proteins for CD44 Interaction Partners

Mouse (Murine) CD44 interaction partners

  1. The high targeting ability of HA-MFNPs was observed at MKN-45 cells (gastric cancer cell line) which high-expressing CD44 in contrast with MKN-28 cells which low-expressing CD44.

  2. the aggravation of pulmonary inflammation upon combined exposure to allergen and an environmental pollutant is CD44-dependent.

  3. CD44 promotes chemoresistance in T-ALL by increased drug efflux.

  4. HA-binding to CD44-expressing beta cells is implicated in beta-cell demise

  5. Suggest CD44 is involved in the development of mucous metaplasia in mice infected with Helicobacter pylori.

  6. CD44 enhances T cell receptor signaling strength by delivering lymphocyte-specific protein kinase (show CDK7 Proteins), which is required for induction of IL-17 (show IL17A Proteins) producing T helper cells

  7. Endogenous hyaluronic acid increases Lgr5 (show LGR5 Proteins)(+) stem cell proliferation, crypt fission, and intestinal lengthening and that these effects are dependent on signaling through CD44 and TLR4 (show TLR4 Proteins).

  8. consistent with CD44's pivotal role in modulating several diverse behaviors important for adhesion, proliferation, apoptosis, migration and invasion during development, growth, repair, maintenance and regression of a wide variety of mesenchymal tissues

  9. The current study reports a unique approach to study H. pylori interaction with the human gastric epithelium. Here, we show that CD44 plays a functional role in H. pylori-induced epithelial cell proliferation.

  10. CD44 and pro-NRG1 (show NRG1 Proteins) are posttranslationally modified at their intracellular domains.

Human CD44 interaction partners

  1. CD44(+)/CD24 (show CD24 Proteins)(-) phenotype may be an important factor for malignant relapse following surgical resection and chemotherapy in patients with invasive ductal carcinoma.

  2. we present evidence that CD44v3 immunoexpression and CD44v3+/CD24 (show CD24 Proteins)- immunophenotypes could give prognostic information associated with unfavorable clinical outcomes.

  3. CD44 expression pattern was significantly correlated with grade of dysplasia in ulcerative colitis

  4. CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Proteins).

  5. CD44S-hyaluronan interactions protect cells resulting from EMT (show ITK Proteins) against anoikis.

  6. The combinatory expression of HOXA10 (show HOXA10 Proteins) and CD44 was correlated with poor gastric cancer prognosis.

  7. CD44 polymorphisms are associated with chronic HBV infection as the risk factors

  8. Basal like tumors are enriched for cancer stem cells (CSC) with CD44(+)/CD24(-/low) phenotype. CD133 can detect a different population of CSC in breast carcinoma

  9. High CD44 expression contributes to the development of carboplatin resistance in advanced serous epithelial ovarian cancer.

  10. Prognostic Significance of CD44v6, CD133, CD166 (show ALCAM Proteins), and ALDH1 (show ALDH1A1 Proteins) Expression in Small Intestinal Adenocarcinoma.

Cow (Bovine) CD44 interaction partners

  1. CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Proteins).

  2. release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.

  3. CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro

  4. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Proteins), CD44, and CD62L (show SELL Proteins) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

  5. detection of CD44 in the bovine oviductal epithelium

  6. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR Proteins)-mediated signalling pathways involving Cdc2 (show CDK1 Proteins) and gamma-adducin (show ADD3 Proteins).

  7. The novel finding that TSP-1 (show THBS1 Proteins)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 Proteins) and HyA (show KDM5D Proteins)).

Horse (Equine) CD44 interaction partners

  1. An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.

CD44 Protein Profile

Protein Summary

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Gene names and symbols associated with CD44 Proteins (CD44)

  • CD44 antigen (Cd44)
  • CD44 antigen-like (LOC100525150)
  • Cd44 molecule (Cd44)
  • CD44 molecule (Indian blood group) (CD44)
  • syndecan 4 (SDC4)
  • AU023126 protein
  • AW121933 protein
  • AW146109 protein
  • CD44A protein
  • CDW44 protein
  • CSPG8 protein
  • ECMR-III protein
  • HCELL protein
  • HERMES protein
  • HUTCH-I protein
  • IN protein
  • LHR protein
  • Ly-24 protein
  • MC56 protein
  • MDU2 protein
  • MDU3 protein
  • METAA protein
  • MIC4 protein
  • Pgp-1 protein
  • Pgp1 protein
  • RHAMM protein

Protein level used designations for CD44 Proteins (CD44)

ECMR-III , GP90 lymphocyte homing/adhesion receptor , HUTCH-I , PGP-I , extracellular matrix receptor III , hermes antigen , hyaluronate receptor , lymphocyte antigen 24 , phagocytic glycoprotein 1 , phagocytic glycoprotein I , CD44 antigen , Cell surface glycoprotein CD44 (hyaluronate binding protein) , PGP-1 , Hermes antigen , cell surface glycoprotein CD44 , chondroitin sulfate proteoglycan 8 , epican , hematopoietic cell E- and L-selectin ligand , heparan sulfate proteoglycan , homing function and Indian blood group system , extracellular matrix receptor-III , CD44-like protein , lymphocyte surface antigen precursor CD44 , syndecan 4 (amphiglycan, ryudocan) , syndecan-4

12505 Mus musculus
100750640 Cricetulus griseus
100525150 Sus scrofa
25406 Rattus norvegicus
960 Homo sapiens
403939 Canis lupus familiaris
101098744 Felis catus
281057 Bos taurus
395666 Gallus gallus
101113884 Ovis aries
100034221 Equus caballus
100301546 Oryctolagus cuniculus
419184 Gallus gallus
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