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CD44 Proteins (CD44)

The protein encoded by CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. Additionally we are shipping CD44 Antibodies (1473) and CD44 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CD44 12505 P15379
CD44 25406  
CD44 960 P16070
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Top CD44 Proteins at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$280.50
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Human His tag   10 μg Log in to see 11 Days
$187.50
Details

CD44 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus) ,

Human , , , , , , , ,
, , , ,

Top referenced CD44 Proteins

  1. Human CD44 Protein expressed in Wheat germ - ABIN1348653 : Gebhard, Jain, Nair, Emmons, Argilagos, Koomen, McLaughlin, Hazlehurst: MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. in Molecular cancer therapeutics 2013 (PubMed)
    Show all 2 references for ABIN1348653

  2. Human CD44 Protein expressed in HEK-293 Cells - ABIN2180800 : Hanley, Burdick, Konstantopoulos, Sackstein: CD44 on LS174T colon carcinoma cells possesses E-selectin ligand activity. in Cancer research 2005 (PubMed)

More Proteins for CD44 Interaction Partners

Mouse (Murine) CD44 interaction partners

  1. These studies demonstrate that both endometrial cell and peritoneal mesothelial cell CD44 play a role in the development of early endometriotic lesion.

  2. Targeting CD44 expressing colon cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin.

  3. MGK as hydrophobic moieties and oHA as the target of CD44 receptor.

  4. CD44, NOD2, and Fas (show FAS Proteins) have distinct functions in regulating changes in trabecular and cortical bone indices during unloading.

  5. The absence of CD44 in neonatal bone marrow has no impact on the size of the long-term reconstituting hematopoietic stem cell pool, but results in an enhanced long-term engraftment potential of hematopoietic stem cells.

  6. CD44 deficiency can reduce osteoclast activity and counteract cortical bone loss in the hindlimb of unloaded mice.

  7. Genetic deficiency of CD44 augments activation, apoptosis and pro-thrombotic potential of platelets.

  8. The high targeting ability of HA-MFNPs was observed at MKN-45 cells (gastric cancer cell line) which high-expressing CD44 in contrast with MKN-28 cells which low-expressing CD44.

  9. the aggravation of pulmonary inflammation upon combined exposure to allergen and an environmental pollutant is CD44-dependent.

  10. CD44 promotes chemoresistance in T-ALL by increased drug efflux.

Pig (Porcine) CD44 interaction partners

  1. Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells

  2. CD44 has a key role in oocyte maturation but not in cumulus expansion.

  3. This study demonstrates that the CD14-negative isolation yields an enhanced cell population SFB that is more potent than MSCP as a cell source for cartilage tissue engineering.

  4. CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.

Human CD44 interaction partners

  1. The ALDH1 (show ALDH1A1 Proteins) activity and sphere forming ability of CD44(high) /ALDH1 (show ALDH1A1 Proteins)(high) cells was significantly inhibited by GSK3beta knockdown. On the other hand, CD44(high) /ALDH1 (show ALDH1A1 Proteins)(low) cells exhibited high epidermal growth factor receptor (EGFR (show EGFR Proteins)) expression and increased cell growth.

  2. Analysis of KRAS mutation combined with immunohistochemical expression of CD44 and CD166 (show ALCAM Proteins) identified subgroups of patients with colon adenocarcinoma at higher risk of lymph node involvement by the tumor and development of liver and lung metastasis.

  3. Study shows that CD44 is an important regulator of glucose metabolism in small cell neuroendocrine carcinoma.

  4. the authors investigated the ability of two hyaluronan-based nanoparticles targeting CD44 receptors to home in on lung cancer cells in an in-vivo orthotropic model. The preferential uptake of smaller sized nanoparticles via intravenous route has further enhanced the existing knowledge of future drug designs.

  5. Although LCN2 increased intracellular iron concentrations, LCN2-induced GSH may catalyze and override oxidative stress via CD44 and xCT, and subsequently enhance the survival of clear cell carcinoma tumor cells in oxidative stress-rich environment.

  6. loss of the CD44 expression plays role in lymphovascular permeation and metastasis and it can be hypothesized that its reexpression at metastatic site may play a role in homing of tumor cells

  7. CD44 and CD133 might participate in early-stage endometrial cancer carcinogenesis

  8. Nuclear CD44 in liver cancer stem cells is responsible for the poorly differentiated highly malignant tumor cells by maintenance of low stemness state.

  9. findings suggested that HIV-1 gp41-I90 ectodomain can enhance the transmigration of THP-1 through Cn-infected BBB, which may be mediated by CD44.

  10. Increased Expression of CD44 mRNA is associated with Recurrence After Curative Resection of Hepatocellular Carcinoma.

Cow (Bovine) CD44 interaction partners

  1. CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (show HYAL2 Proteins).

  2. release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.

  3. CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro

  4. determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (show IL2RA Proteins), CD44, and CD62L (show SELL Proteins) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.

  5. detection of CD44 in the bovine oviductal epithelium

  6. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (show HMMR Proteins)-mediated signalling pathways involving Cdc2 (show CDK1 Proteins) and gamma-adducin (show ADD3 Proteins).

  7. The novel finding that TSP-1 (show THBS1 Proteins)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (show THBS1 Proteins) and HyA (show KDM5D Proteins)).

Horse (Equine) CD44 interaction partners

  1. An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.

CD44 Protein Profile

Protein Summary

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Gene names and symbols associated with CD44 Proteins (CD44)

  • CD44 antigen (Cd44)
  • CD44 antigen-like (LOC100525150)
  • Cd44 molecule (Cd44)
  • CD44 molecule (Indian blood group) (CD44)
  • syndecan 4 (SDC4)
  • AU023126 protein
  • AW121933 protein
  • AW146109 protein
  • CD44A protein
  • CDW44 protein
  • CSPG8 protein
  • ECMR-III protein
  • HCELL protein
  • HERMES protein
  • HUTCH-I protein
  • IN protein
  • LHR protein
  • Ly-24 protein
  • MC56 protein
  • MDU2 protein
  • MDU3 protein
  • METAA protein
  • MIC4 protein
  • Pgp-1 protein
  • Pgp1 protein
  • RHAMM protein

Protein level used designations for CD44 Proteins (CD44)

ECMR-III , GP90 lymphocyte homing/adhesion receptor , HUTCH-I , PGP-I , extracellular matrix receptor III , hermes antigen , hyaluronate receptor , lymphocyte antigen 24 , phagocytic glycoprotein 1 , phagocytic glycoprotein I , CD44 antigen , Cell surface glycoprotein CD44 (hyaluronate binding protein) , PGP-1 , Hermes antigen , cell surface glycoprotein CD44 , chondroitin sulfate proteoglycan 8 , epican , hematopoietic cell E- and L-selectin ligand , heparan sulfate proteoglycan , homing function and Indian blood group system , extracellular matrix receptor-III , CD44-like protein , lymphocyte surface antigen precursor CD44 , syndecan 4 (amphiglycan, ryudocan) , syndecan-4

GENE ID SPECIES
12505 Mus musculus
100750640 Cricetulus griseus
100525150 Sus scrofa
25406 Rattus norvegicus
960 Homo sapiens
403939 Canis lupus familiaris
101098744 Felis catus
281057 Bos taurus
395666 Gallus gallus
101113884 Ovis aries
100034221 Equus caballus
100301546 Oryctolagus cuniculus
419184 Gallus gallus
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