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Calcitonin-Related Polypeptide alpha Proteins (CALCA)

CALCA encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Additionally we are shipping CGRP Antibodies (256) and CGRP Kits (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CALCA 796 P06881,P01258
CALCA 24241 P01256,P01257
Mouse CALCA CALCA 12310 Q99JA0,P70160
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Showing 8 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
HOST_Synthetic Human Un-conjugated   0.1 mg Log in to see 11 to 16 Days
HOST_Escherichia coli (E. coli) Chicken Un-conjugated 100 μg Log in to see 11 to 13 Days

CALCA Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Rat (Rattus)

More Proteins for Calcitonin-Related Polypeptide alpha (CALCA) Interaction Partners

Cow (Bovine) Calcitonin-Related Polypeptide alpha (CALCA) interaction partners

  1. This report is the first to indicate lowered concentrations of calcitonin gene-related peptide (CGRP) as part of the metabolic changes during milk fever in cows.

Rabbit Calcitonin-Related Polypeptide alpha (CALCA) interaction partners

  1. Dynamic monitoring and comparison of plasma levels of ET, CGRP, NO, and MDA as well as SOD activity revealed that appropriate intervention of these factors may reduce reperfusion injury

  2. The reciprocal changes in SST (show SST Proteins) and histamine secretion in gastric Helicobacter infection were due to release of CGRP from sensory neurons.

  3. Substance P (show TAC1 Proteins) and CGRP correlate with the occurrence and development of allergic rhinitis.

Human Calcitonin-Related Polypeptide alpha (CALCA) interaction partners

  1. Calcitonin is specifically expressed in sera of medullary thyroid carcinoma patients. (Review)

  2. Peripheral actions of CGRP (show S100A12 Proteins) in the joint might contribute to both inflammation and joint afferent sensitization.

  3. Among adrenomedullin (show ADM Proteins), CRP (show CRP Proteins), and PCT (show UROD Proteins), procalcitonin demonstrates the highest correlation with the severity of infection.

  4. The study simultaneously evaluated both PCT (show UROD Proteins) and soluble TREM-1 (show TREM1 Proteins) along with CRP (show CRP Proteins) in febrile patients with autoimmune diseases.

  5. In absence of other nosocomial infections, early high serum PCT (show UROD Proteins) concentrations appear to be a reliable indicator of bacterial CNS infection in patients with external ventricular drains.

  6. blood PCT (show UROD Proteins) sufficient to confirm or exclude bacterial meningitis diagnosis [meta-analysis]

  7. Procalcitonin, uric acid, and BNP had significant relationship with many echocardiographic findings in participants. For patients, procalcitonin did not show correlation.

  8. NGAL (show LCN2 Proteins) and procalcitonin may be potential biomarkers for preeclampsia. Their levels increase significantly in preeclampsia and they are related to the severity of the disease.

  9. PCT (show UROD Proteins) level was not significantly different in neutropenic systemic inflammatory response syndrome patients and sepsis patients.

  10. The highest levels of procalcitonin (PCT (show UROD Proteins)) were found in patients with bacteremia caused by Streptococcus pneumoniae serotypes 7F, 19A, 3 & 1. PCT (show UROD Proteins) levels were able to predict bacteremia (caused by S. pneumoniae or not) in patients with pneumonia.

Pig (Porcine) Calcitonin-Related Polypeptide alpha (CALCA) interaction partners

  1. High level of co-expression of PACAP (show ADCYAP1 Proteins) with VIP (show Vip Proteins), SP and CGRP in the distal ganglia of the vagus sensory perikarya directly implicates studied peptides in their functional interaction during nociceptive vagal transduction.

  2. This study demonstrated for the first time a strong expression of NGF, TrkA, CGRP, nNOS and neuronal specific enolase in the majority of esophageal enteric nervous system components.

  3. Localization of calcitonin gene related peptide in the nerve fibers of porcine cystic ovaries

  4. Calcitonin is a regulator of the 25-hydroxyvitamin D3 1alpha-hydroxylase (show CYP27B1 Proteins) gene.

  5. CGRP-antibodies can be used as markers for type II neurons in the pig small intestinal myenteric plexus in quantitative studies but it should be kept in mind that up to one-tenth of CGRP-reactive neurons may be non-type II neurons.

  6. The data provide morphological evidence confirming expression of CGRP in the porcine spinal nuclei while its coexpression in cholinergic neurons suggests that CGRP may play a role in modulation of the spinal cholinergic transmission.

Mouse (Murine) Calcitonin-Related Polypeptide alpha (CALCA) interaction partners

  1. Suggest that cochlear function is enhanced by maturation of CGRP receptor complexes.

  2. the generation of Tregs may be promoted by naive CD4 (show CD4 Proteins)+ T cell: neuron interaction through the release of neuropeptide CGRP.

  3. The observations of this study imply that Adelta afferents expressing CGRP-IR transduce information from different sites within the skin.

  4. SHH (show SHH Proteins) may affect alveolar bone healing by interacting with CGRP-positive sensory neurons and thus regulate the socket's healing process after tooth extraction.

  5. TRPM8 (show TRPM8 Proteins) signaling in mucosal sensory neurons is indispensable for the regulation of innate inflammatory responses via the neuropeptide CGRP.

  6. CGRP suppresses the development of leaky choroidal neovascularization through negative regulation of inflammation.

  7. CT has a role in skeletal biology and S1P (show S1PR1 Proteins) acts as an osteoanabolic molecule and has a role in crosstalk between osteoclasts and osteoblasts

  8. CGRP is an inhibitory transmitter that shapes peripheral taste signals via serotonergic signaling during processing gustatory information in taste buds.

  9. The increased responsiveness to intraplantar calcitonin gene-related peptide suggests that the peripheral actions of calcitonin gene-related peptide are enhanced as a result of the neurofibromin (show NF1 Proteins) deficit.

  10. This study provides direct ultrastructural evidences for the synaptic contacts between CGRP-positive terminals and GABAergic neurons within the central nucleus of amygdala.

CGRP (CALCA) Protein Profile

Protein Summary

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CALCA

  • calcitonin-related polypeptide alpha (CALCA)
  • Calcitonin gene-related peptide (calca)
  • calcitonin (ci-ct)
  • calcitonin (CALCA)
  • calcitonin (CT)
  • calcitonin gene-related peptide (LOC100008771)
  • calcitonin-related polypeptide alpha (Calca)
  • calcitonin-related polypeptide beta (CALCB)
  • calcitonin/calcitonin-related polypeptide, alpha (Calca)
  • CA protein
  • Cal1 protein
  • CAL6 protein
  • Calc protein
  • Calc1 protein
  • CALC3 protein
  • calca protein
  • calcitonin protein
  • Cgrp protein
  • CGRP-1 protein
  • CGRP-I protein
  • CGRP1 protein
  • CGRPI protein
  • ci-ct protein
  • Ct protein
  • Ctn protein
  • KC protein
  • RATCAL6 protein

Protein level used designations for CALCA

calcitonin gene-related peptide 2 , calcitonin-related polypeptide 3 , calcitonin-related polypeptide alpha , calcitonin , calcitonin/calcitonin-related polypeptide, alpha , Calcitonin gene-related peptide , calcitonin gene-related peptide , alpha-type CGRP , calcitonin 1 , calcitonin gene-related peptide I , katacalcin , CGRP-I , calcitonin gene-related peptide 1 , calcitonin gene related peptide I , calcitonin-related polypeptide, beta , alpha CGRP , calcitonin/alpha CGRP

614663 Bos taurus
748619 Pan troglodytes
100286641 Salmo salar
100329144 Ciona intestinalis
396256 Gallus gallus
514876 Bos taurus
100008771 Oryctolagus cuniculus
796 Homo sapiens
24241 Rattus norvegicus
403946 Canis lupus familiaris
100033906 Equus caballus
100579174 Sus scrofa
100294596 Ovis aries
100124407 Sus scrofa
12310 Mus musculus
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