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anti-Cathepsin K (CTSK) Antibodies

The protein encoded by CTSK is a lysosomal cysteine proteinase involved in bone remodeling and resorption. Additionally we are shipping Cathepsin K Kits (68) and Cathepsin K Proteins (33) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CTSK 1513 P43235
CTSK 13038 P55097
CTSK 29175 O35186
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Top anti-Cathepsin K Antibodies at

Showing 10 out of 172 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
Chicken Rabbit Un-conjugated IP, IHC, WB Western blot analysis of Cathepsin K with rat kidney tissue lysate. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB AP51131PU-N Cathepsin K Antibody flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Formalin fixed and paraffin embedded human skeletal muscle stained with CTSK Antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. 0.4 mL Log in to see 6 to 8 Days
Human Goat Un-conjugated ELISA, WB ABIN263224 (1µg/ml) staining of Human Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
Cow Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IP, IHC, WB Western blot analysis of Cathepsin K expression in MCF7 cell lysate. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB WB Suggested Anti-CTSK AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Liver 100 μL Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated IHC, WB 100 μL Log in to see 9 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Formalin-fixed and paraffin-embedded human breast carcinoma with CTSK Antibody (Center R222), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Flow cytometric analysis of ZR-75-1 cells using CTSK Antibody (Center R222)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days

CTSK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,

Rat (Rattus)

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Top referenced anti-Cathepsin K Antibodies

  1. Mouse (Murine) Polyclonal Cathepsin K Primary Antibody for IHC, WB - ABIN3022539 : Xiao, Junfeng, Tianhong, Lu, Shulin, Yu, Xiaohua, Weixia, Sheng, Yanyun, Guo, Min: Cathepsin K in adipocyte differentiation and its potential role in the pathogenesis of obesity. in The Journal of clinical endocrinology and metabolism 2006 (PubMed)
    Show all 3 references for ABIN3022539

  2. Human Polyclonal Cathepsin K Primary Antibody for EIA, IHC (p) - ABIN951065 : Novinec, Kovacic, Lenarcic, Baici: Conformational flexibility and allosteric regulation of cathepsin K. in The Biochemical journal 2010 (PubMed)
    Show all 3 references for ABIN951065

  3. Chicken Polyclonal Cathepsin K Primary Antibody for IP, IHC - ABIN223282 : López-Guisa, Cai, Collins, Yamaguchi, Okamura, Bugge, Isacke, Emson, Turner, Shankland, Eddy: Mannose receptor 2 attenuates renal fibrosis. in Journal of the American Society of Nephrology : JASN 2012 (PubMed)
    Show all 2 references for ABIN223282

  4. Human Polyclonal Cathepsin K Primary Antibody for EIA, WB - ABIN452891 : Lendeckel, Kähne, Ten Have, Bukowska, Wolke, Bogerts, Keilhoff, Bernstein: Cathepsin K generates enkephalin from beta-endorphin: a new mechanism with possible relevance for schizophrenia. in Neurochemistry international 2009 (PubMed)

  5. Cow (Bovine) Polyclonal Cathepsin K Primary Antibody for EIA, WB - ABIN374971 : Asagiri, Hirai, Kunigami, Kamano, Gober, Okamoto, Nishikawa, Latz, Golenbock, Aoki, Ohya, Imai, Morishita, Miyazono, Kato, Saftig, Takayanagi: Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. in Science (New York, N.Y.) 2008 (PubMed)

More Antibodies against Cathepsin K Interaction Partners

Human Cathepsin K (CTSK) interaction partners

  1. There is an increase in levels of CATK in type 1 Gaucher patients compared to the control group. In the patient group, CATK showed higher levels in patients with bone damage compared to those without it.

  2. elevated levels of CatK are closely associated with the presence of chronic heart failure and that the measurement of circulating CatK provides a noninvasive method of documenting and monitoring the extent of chronic heart failure

  3. Cathepsins in Rotator Cuff (show CUFF Antibodies) Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model.

  4. Matrix-metalloproteinase-9 (show MMP9 Antibodies) is cleaved and activated by cathepsin K.

  5. Sequence analysis of the patient's CTSK gene revealed homozygosity for a missense mutation (c.746T>C) in exon 6, which leads to amino change (p.Ile249Thr) in the mature CTSK protein

  6. The presence of high levels of inactive proforms of cathepsin K in GBM tissues and cells indicate that in GBM the proteolytic/collagenolytic role is not its primary function but it plays rather a different yet unknown role.

  7. Two compounds have sizable effects on enzyme activity using interstitial collagen as a natural substrate of cathepsin K and four compounds show a significantly stabilizing effect on cathepsin K.

  8. Studies indicate cathepsin X as a target for improving diagnosis and treating cancer patients.

  9. SDF-1alpha is involved in homing of CXCR4 (show CXCR4 Antibodies)+ GSLCs and leukocytes and that cathepsin K and osteopontin (show SPP1 Antibodies) are involved in the migration of GSLCs out of the niches

  10. one cathepsin K molecule binds to collagen-bound glycosaminoglycans at the gap region and recruits a second protease molecule that provides an unfolding and cleavage mechanism for triple helical collagen

Pig (Porcine) Cathepsin K (CTSK) interaction partners

  1. The CTSK marker was associated with back fat thickness and lean cuts (P < 0.01), and average daily gain and feed:gain ratio (P < 0.05) estimated breeding values.

Rabbit Cathepsin K (CTSK) interaction partners

  1. The authors showed CTSK upregulation in human lung specimens and elevated serum CTSK levels of patients with tuberculosis, compared with controls.

  2. Down-regulation of cathepsin K in synovium at the initial stage of osteoarthritis significantly accelerated cartilage degeneration.

Mouse (Murine) Cathepsin K (CTSK) interaction partners

  1. The effects of muscarinic receptor (show CHRM5 Antibodies) M3 knockout on cathepsin K expression, bone density and biomechanical properties of bone are reported.

  2. Cathepsin K expression is increased in the bone of a diabetic mouse model.

  3. Data suggest Ctsk gene, key gene upregulated during osteoclast differentiation, is transcriptionally activated during cell hypoxia-induced mitochondrial dysfunction/disruption; hnRNPA2 (heterogeneous ribonucleoprotein A2) is coactivator in this process.

  4. cathepsin K knockout attenuates age-related decline in cardiac function via suppressing caspase (show CASP3 Antibodies)-dependent and caspase (show CASP3 Antibodies)-independent apoptosis

  5. Data (including data from studies in knockout/transgenic mice) suggest that Ctsk is involved in inflammatory response and bone resorption in both rheumatoid arthritis and periodontitis; thus, Ctsk appears to play a role in osteoimmune responses.

  6. In a mouse model of post-traumatic osteoarthritis, cathepsin K activity was significantly increased in injured knees relative to uninjured knees.

  7. Gene deletion of cathepsin K in mice accelerated callus size resolution, significantly increased callus mineralized mass, and improved mechanical strength as compared to wild type mice.

  8. synergism between HIV proteins and pro-atherogenic shear stress to increase endothelial cell expression of the powerful protease cathepsin K

  9. in addition to its other effects, the absence of CatK in OCP limits their ability to engraft in a repairing fracture callus compared to WT OCP.

  10. Cardiac mammalian target of rapamycin (show FRAP1 Antibodies) and extracellular signal-regulated kinases (ERK (show EPHB2 Antibodies)) signaling cascades were upregulated by pressure overload, the effects of which were attenuated by cathepsin K knockout.

Cathepsin K (CTSK) Antigen Profile

Protein Summary

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Gene names and symbols associated with anti-Cathepsin K (CTSK) Antibodies

  • cathepsin K-like (LOC100054991) antibody
  • 26-29kD-proteinase (26-29-p) antibody
  • cathepsin K (CTSK) antibody
  • cathepsin K (ctsk) antibody
  • Cathepsin K (catk) antibody
  • cathepsin O (CTSO) antibody
  • cathepsin K (catk) antibody
  • cathepsin K (Ctsk) antibody
  • 26/29kD-proteinase antibody
  • AI323530 antibody
  • anon-SAGE:Wang-123 antibody
  • catK antibody
  • CG8947 antibody
  • CTS02 antibody
  • CTSK antibody
  • CTSO antibody
  • CTSO1 antibody
  • CTSO2 antibody
  • Dmel\\CG8947 antibody
  • l(3)s3635 antibody
  • MMS10-Q antibody
  • Ms10q antibody
  • OC-2 antibody
  • PKND antibody
  • PYCD antibody
  • wu:fa95f03 antibody
  • wu:fb08b05 antibody
  • zgc:110367 antibody

Protein level used designations for anti-Cathepsin K (CTSK) Antibodies

26,29kDa proteinase , 26-29 kD-proteinase , 26-29-p-PA , 26-29kDa proteinase , 26-29kd prot , CG8947-PA , anon-SAGE:Wang-123 , cathepsin K , etID33526.16 , Cathepsin K , cathepsin O , cathepsin O1 , cathepsin O2 , cathepsin X , JTAP-1 , protein OC-2 , Cat K , minisatellite 10q detected by probe MMS10 , cathepsin K (pycnodysostosis) , cathepsin K preproprotein

100054991 Equus caballus
39547 Drosophila melanogaster
457278 Pan troglodytes
550475 Danio rerio
779889 Xenopus (Silurana) tropicalis
100127265 Xenopus laevis
100195370 Salmo salar
461567 Pan troglodytes
482665 Canis lupus familiaris
616804 Bos taurus
699868 Macaca mulatta
100528180 Ictalurus punctatus
1513 Homo sapiens
395818 Gallus gallus
397569 Sus scrofa
100009334 Oryctolagus cuniculus
13038 Mus musculus
29175 Rattus norvegicus
608843 Canis lupus familiaris
513038 Bos taurus
100718267 Cavia porcellus
101108972 Ovis aries
574112 Macaca mulatta
Selected quality suppliers for anti-Cathepsin K (CTSK) Antibodies
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