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Caspase 8 Antibodies

(Caspase 8 (CASP8))
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq, Jul 2008].
Caspase 8 antibody  (AA 411-482) Caspase 8 antibody  (AA 411-482) Caspase 8 antibody (AA 411-482) (ABIN724205)

CASP8 Reactivity: Human, Mouse, Rat, Monkey, Pig, Sheep ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB Host: Rabbit Polyclonal unconjugated

Caspase 8 antibody  (AA 1-479) Caspase 8 antibody  (AA 1-479) Caspase 8 antibody (AA 1-479) (ABIN6137970)

CASP8 Reactivity: Human IF, IHC, WB Host: Rabbit Polyclonal unconjugated

Caspase 8 antibody  (AA 217-384) Caspase 8 antibody  (AA 217-384) Caspase 8 antibody (AA 217-384) (ABIN7432745)

CASP8 Reactivity: Human ICC, IHC, IP, WB Host: Rabbit Polyclonal unconjugated

Caspase 8 Antibodies by Reactivity

Find Caspase 8 Antibodies for a variety of species such as anti-Human Caspase 8, anti-Mouse Caspase 8, anti-Rat Caspase 8. The species listed below are among those available. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Application

Find Caspase 8 Antibodies validated for a specific application such as WB, IHC, ELISA, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Host

Find Caspase 8 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Binding Specificity

Find Caspase 8 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Clonality

Find available monoclonal or polyclonal Caspase 8 Antibodies. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Clone

Find Caspase 8 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Caspase 8 Antibodies by Conjugate

Find Caspase 8 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Caspase 8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey, Mouse, Pig, Rat, Sheep
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (15)
  • (5)
  • (1)
Cat. No. ABIN724205
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC, WB
Validations
  • (17)
  • (12)
Cat. No. ABIN6137970
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • (9)
Cat. No. ABIN7432745
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • (9)
Cat. No. ABIN7437074
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
  • (10)
Cat. No. ABIN7444115
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (4)
  • (5)
Cat. No. ABIN1386778
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application FACS, IHC, ELISA, WB
Validations
  • (2)
  • (5)
Cat. No. ABIN969003
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application EIA, FACS, IHC (p), WB
Validations
  • (5)
Cat. No. ABIN1105678
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN7202063
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN7146964
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, IHC, WB
Validations
  • (4)
Cat. No. ABIN6256281
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application FACS, IHC, ELISA, WB
Validations
  • (4)
Cat. No. ABIN2745525
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (14)
  • (2)
Cat. No. ABIN3044129
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, IP, WB
Validations
  • (3)
Cat. No. ABIN7432748
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC (p), WB
Validations
  • (3)
Cat. No. ABIN7202064
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Caspase 8 Antibodies

Chen, Deng, Gan, Li, Huang, Lu, Wei, Su, Luo, Zou, Hong, Cao, Liu, Chi: "NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma." in: Molecular neurodegeneration, Vol. 15, Issue 1, pp. 26, (2020) (PubMed).

Song, Ma, Lu, Zhou, Zhao, Ai, Wei, Lin, Wang, Yan, Jiao: "The protective role of the MKP-5-JNK/P38 pathway in glucolipotoxicity-induced islet β-cell dysfunction and apoptosis." in: Experimental cell research, Vol. 382, Issue 1, pp. 111467, (2020) (PubMed).

Kong, Liu, Zhou, Hou, He, Li, Miao, Yang: "Downregulation of METTL14 increases apoptosis and autophagy induced by cisplatin in pancreatic cancer cells." in: The international journal of biochemistry & cell biology, Vol. 122, pp. 105731, (2020) (PubMed).

Zhao, Zhu, Bu, Zhou, Bai, Guo, Gao, Lu: "Triggering apoptosis by oroxylin A through caspase-8 activation and p62/SQSTM1 proteolysis." in: Redox biology, Vol. 29, pp. 101392, (2020) (PubMed).

Zhou, Li, Han, Feng, Liu, Chen, Liu, Zhao, Jin: "Emodin induced necroptosis in the glioma cell line U251 via the TNF-α/RIP1/RIP3 pathway." in: Investigational new drugs, Vol. 38, Issue 1, pp. 50-59, (2020) (PubMed).

Chen, Fang, Chen, Yang, Zhou, Mao, Xia, Jin, Li, You, Wang, Lei, He, Hu: "Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain-barrier disruption after ischemic stroke." in: Cell death & disease, Vol. 10, Issue 7, pp. 487, (2020) (PubMed).

Hu, Li, Yu, Liu, Wang, Qing, Wang, Wang, Zhu, Xu, Tan, Guo, Hui: "GL-V9 exerts anti-T cell malignancies effects via promoting lysosome-dependent AKT1 degradation and activating AKT1/FOXO3A/BIM axis." in: Free radical biology & medicine, Vol. 145, pp. 237-249, (2020) (PubMed).

Jin, Shi, Liu, Chen, Yang: "Xanthones from the Bark of Garcinia xanthochymus and the Mechanism of Induced Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells via the Mitochondrial Pathway." in: International journal of molecular sciences, Vol. 20, Issue 19, (2020) (PubMed).

Yu, Ye, Li, Zhan, Liu, Yan, Fang, Xie, Zhang, Chen, Ding, Chen: "Histone methyltransferase SETDB1 promotes colorectal cancer proliferation through the STAT1-CCND1/CDK6 axis." in: Carcinogenesis, Vol. 41, Issue 5, pp. 678-688, (2020) (PubMed).

Liu, Wei, Fang, Li, Li: "Giardia duodenalis induces extrinsic pathway of apoptosis in intestinal epithelial cells through activation of TNFR1 and K63 de-ubiquitination of RIP1 in vitro." in: Microbial pathogenesis, Vol. 149, pp. 104315, (2020) (PubMed).

Aliases for Caspase 8 Antibodies

caspase 8 L homeolog (casp8.L) Antibodies
death related ced-3/Nedd2-like protein (LOC661095) Antibodies
caspase 8 (CASP8) Antibodies
caspase-8 (LOC5563818) Antibodies
caspase-8 (casp8) Antibodies
caspase-8-like (LOC100222284) Antibodies
caspase 8 (Casp8) Antibodies
caspase 8, apoptosis-related cysteine peptidase (casp8) Antibodies
ALPS2B Antibodies
CAP4 Antibodies
CASP-8 Antibodies
Casp-8 Antibodies
casp8 Antibodies
CASP8 Antibodies
casp8-A Antibodies
caspase-8 Antibodies
FLICE Antibodies
MACH Antibodies
Mch5 Antibodies
MCH5 Antibodies
xCaspase-8 Antibodies
zgc:92075 Antibodies
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