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Cathepsin K antibody (Middle Region)

CTSK Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN951065
  • Target See all Cathepsin K (CTSK) Antibodies
    Cathepsin K (CTSK)
    Binding Specificity
    • 14
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 96-126, Middle Region
    Reactivity
    • 57
    • 30
    • 23
    • 9
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 24
    • 1
    Rabbit
    Clonality
    • 61
    • 23
    Polyclonal
    Conjugate
    • 47
    • 11
    • 10
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cathepsin K antibody is un-conjugated
    Application
    • 66
    • 33
    • 23
    • 15
    • 11
    • 10
    • 8
    • 8
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human Cathepsin K.
    Cross-Reactivity (Details)
    Species reactivity (expected):Bovine, MonkeySpecies reactivity (tested):Human
    Purification
    Saturated Ammonium Sulfate (SAS) Precipitation
    Immunogen
    KLH conjugated synthetic peptide between 96-126 amino acids from the Central region of Human Cathepsin K Genename: CTSK
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CTSK Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Cathepsin K (CTSK)
    Alternative Name
    Cathepsin K (CTSK Products)
    Synonyms
    CTS02 antibody, CTSO antibody, CTSO1 antibody, CTSO2 antibody, PKND antibody, PYCD antibody, AI323530 antibody, MMS10-Q antibody, Ms10q antibody, catK antibody, CTSK antibody, wu:fa95f03 antibody, wu:fb08b05 antibody, zgc:110367 antibody, cts02 antibody, ctso antibody, ctso1 antibody, ctso2 antibody, pknd antibody, pycd antibody, OC-2 antibody, catk antibody, cathepsin K antibody, cathepsin K L homeolog antibody, Cathepsin K antibody, CTSK antibody, Ctsk antibody, ctsk antibody, ctsk.L antibody, catk antibody
    Background
    The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X
    Molecular Weight
    36966 Da
    Gene ID
    1513
    NCBI Accession
    NP_000387
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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