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anti-Chemokine (C-X-C Motif) Receptor 2 (CXCR2) Antibodies

The protein encoded by CXCR2 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR2 Kits (27) and CXCR2 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CXCR2 3579 P25025
CXCR2 12765 P35343
CXCR2 29385 P35407
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Top anti-CXCR2 Antibodies at antibodies-online.com

Showing 10 out of 255 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-IL8RB Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (fro), IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of Jurkat (lanes 1 and 4), SH-SY5Y (lanes 2 and 5) and THP-1 (lanes 3 and 6) lysates: 1-3. Anti-CXCR2 (extracellular) antibody, (1:200). 4-6. Anti-CXCR2 (extracellular) antibody, preincubated with the control peptide antigen. Anti-CXCR2_(extracellular) - Indirect flow cytometry analysis of intact live Jurkat cells: Indirect flow cytometry analysis of intact live Jurkat cells: Black: Unstained cells. Green: Cells + Anti-CXCR2 (extracellular) antibody, (5-10 µg/5x105 cells). 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Mouse PE FACS Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB PE-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$140.44
Details
Human Mouse Fluorescein FACS Detection of CXCR2/IL-8 RB in Human Peripheral Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$140.44
Details
Human Mouse Allophycocyanin FACS Detection of CXCR2/IL-8 RB in Human Blood Granulocytes by Flow Cytometry. 25 Tests Log in to see 6 to 7 Days
$144.38
Details
Mouse Rat Allophycocyanin FACS Detection of CXCR2/IL-8 RB in HEK293 Human Cell Line Transfected with Mouse CXCR2/IL-8 RB and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR2/IL-8 RB or (B) mouse CXCR1/IL-8 RA and eGFP was stained with Rat Anti-Mouse CXCR2/IL-8 RB APC-conjugated Monoclonal Antibody. Detection of CXCR2/IL-8 RB in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Rat Anti-Mouse Gr-1/Ly-6G Fluorescein-conjugated Monoclonal Antibody. 25 Tests Log in to see 6 to 7 Days
$152.25
Details
Human Mouse Un-conjugated FACS, IHC, Neut Chemotaxis Induced by CXCL1/GRO alpha and Neutralization by Human CXCR2/IL-8 RB Antibody. Recombinant Human CXCL1/GRO alpha. The ND50 is typically 1-5 ug/mL. Detection of CXCR2/IL-8 RB in Human Blood Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human CXCR2/IL-8 RB Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$345.19
Details
Mouse Rat Un-conjugated FACS, Neut Chemotaxis Induced by CXCL2/MIP-2 and Neutralization by Mouse CXCR2/IL-8 RB Antibody. Recombinant Mouse CXCL2/MIP-2. The ND50 is typically 15-50 ug/mL. Detection of CXCR2/IL-8 RB in HEK293 Human Cell Line Transfected with Mouse CXCR2/IL-8 RB and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) mouse CXCR2/IL-8 RB or (B) mouse CXCR1/IL-8 RA and eGFP was stained with Rat Anti-Mouse CXCR2/IL-8 RB Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$357.00
Details
Human Mouse PE FACS   25 Tests Log in to see 6 to 8 Days
$198.00
Details

CXCR2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-CXCR2 Antibodies

  1. Human Monoclonal CXCR2 Primary Antibody for FACS, IHC - ABIN4899080 : Keane, Donnelly, Belperio, Goodman, Dy, Burdick, Fishbein, Strieter: Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 30 references for ABIN4899080

  2. Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS, Neut - ABIN4899087 : Bi, Zhou, Yang, Wang, Zhang, Wang, Wu, Han, Song, Tan, Du, Yang, Zhou, Cui, Zhou, Yan, Zhang, Guo, Wang, Liu, Yang: IL-17A produced by neutrophils protects against pneumonic plague through orchestrating IFN-γ-activated macrophage programming. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)
    Show all 18 references for ABIN4899087

  3. Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895453 : Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 6 references for ABIN4895453

  4. Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895449 : Mihara, Smit, Krajnc-Franken, Gossen, Rooseboom, Dokter: Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. in European journal of immunology 2005 (PubMed)
    Show all 4 references for ABIN4895449

  5. Human Polyclonal CXCR2 Primary Antibody for EIA, IHC (fro) - ABIN492888 : Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003 (PubMed)
    Show all 4 references for ABIN492888

  6. Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895472 : Citro, Valle, Cantarelli, Mercalli, Pellegrini, Liberati, Daffonchio, Kastsiuchenka, Ruffini, Battaglia, Allegretti, Piemonti: CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice. in Diabetes 2015 (PubMed)
    Show all 3 references for ABIN4895472

  7. Human Polyclonal CXCR2 Primary Antibody for FACS, WB - ABIN1742104 : Pagé, Robitaille, Pouysségur, Richard: Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN1742104

  8. Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN319852 : Petering, Götze, Kimmig, Smolarski, Kapp, Elsner: The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils. in Blood 1999 (PubMed)

  9. Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895445 : Pokkali, Das, R: Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. in Cytokine 2008 (PubMed)

  10. Human Polyclonal CXCR2 Primary Antibody for WB - ABIN2777085 : Gauvreau, Boulet, Cockcroft, Baatjes, Cote, Deschesnes, Davis, Strinich, Howie, Duong, Watson, Renzi, OByrne: Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. in American journal of respiratory and critical care medicine 2008 (PubMed)

More Antibodies against CXCR2 Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. Our findings suggest that CXCL3 (show CXCL3 Antibodies) and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

  2. Data suggest that neutrophil-activating peptide 2 (NAP-2 (show PPBP Antibodies)) secreted by NK cells can bind to CXC Chemokine Receptor (show CXCR4 Antibodies) 2 (CXCR2) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.

  3. High CXCR2 expression is associated with pancreatic cancer.

  4. These data provide rationale that targeting CXCR1 (show CXCR1 Antibodies)/2 with small molecule inhibitors may enhance chemotherapeutic efficacy for the treatment of gastric cancer.

  5. Letter: cold temperatures up regulate CXCR2 ligand Il8 (show IL8 Antibodies) in microvascular endothelial cells which may contribute to neutrophil recruitment and inflammation in skin from patients with livedo vasculopathy with winter ulcerations.

  6. The results showed that the expression of N-Ac-PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP.

  7. The results of this study show that the CXCR2 rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Antibodies) genes.

  8. These studies provide direct evidence linking the activation of IL8 (show IL8 Antibodies), DNA demethylation and the induction of the OA process with important therapeutic implications therein for patients with this debilitating disease.

  9. Studied the expression of CXCL8 (show IL8 Antibodies)-CXCR1 (show CXCR1 Antibodies)/2 pathway, its impact on cell proliferation and cytokine expression in human colorectal carcinoma HCT116 cells.

  10. Inhibition of IL-8 (show IL8 Antibodies) signalling can enhance response in platinum sensitive and resistant high grade serous ovarian carcinoma.

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. Results also demonstrated that in CXCR2 (show CXCR1 Antibodies), genotypes BC, CC and FF were probably relevant with mastitis and the genotypes AA, AB and EE may have better milk quality.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. CXCR2/CXCL1 (show CXCL1 Antibodies) axis promotes granulocytic myeloid-derived suppressor cells recruitment and facilitates arginase I (show ARG1 Antibodies) expression and activity of these cells at maternal-fetal interface

  2. CXCR2 plays a critical role in particle-induced osteolysis.

  3. This study demonstated that endothelial CXCR2 play essential roles in cerebral endothelial activation and subsequent leukocyte recruitment during neuroinflammation.

  4. Studied DC-specific TLR4 (show TLR4 Antibodies) signaling on host defense against intra-abdominal polymicrobial sepsis; found TLR4 (show TLR4 Antibodies) deletion on DCs was associated with lower levels of IL-10 (show IL10 Antibodies), higher PMN (show TBCE Antibodies) accumulation in the peritoneal cavity, and higher expression of CXCR2.

  5. CXCL1 (show CXCL1 Antibodies) monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 activation

  6. p53 (show TP53 Antibodies)-mediated induction of PAI-1 (show SERPINE1 Antibodies) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1 (show CXCL1 Antibodies), CXCL2 (show CXCL2 Antibodies), and CXCR2.

  7. Suggest chemotherapy-specific differential regulation of CXCR2 ligands, stem cell-like and mesenchymal phenotypes, and enhanced metastasis in drug-resistant cells and targeting CXCR2 signaling, may help circumvent therapy resistance in breast cancer.

  8. Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Antibodies) via TLR2 (show TLR2 Antibodies) and directly synergizes with this chemokine (show CCL1 Antibodies) via CXCR2 and formyl peptide receptor 2 (show FPR2 Antibodies) to recruit neutrophils.

  9. Blockade of CXCR2 during Hpb challenge infection reproduced the delayed wound repair observed in helminth infected Aid-/- and Fcrg (show FCER1G Antibodies)-/- mice.

  10. CXCR2 and CX3CR1 (show CX3CR1 Antibodies) differentially regulate EPC (show TCF21 Antibodies) functional responses during atheroregression

CXCR2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with CXCR2

  • chemokine (C-X-C motif) receptor 2 (Cxcr2) antibody
  • chemokine (C-X-C motif) receptor 2 (CXCR2) antibody
  • chemokine (C-X-C motif) receptor 2 (IL8RB) antibody
  • interleukin 8 receptor, beta (CXCR2) antibody
  • CD128 antibody
  • CD182 antibody
  • CDw128 antibody
  • CDw128b antibody
  • Cmkar2 antibody
  • CXC-R2 antibody
  • CXCR-2 antibody
  • Gpcr16 antibody
  • IL-8rb antibody
  • IL-8Rh antibody
  • IL8R2 antibody
  • IL8RA antibody
  • Il8rb antibody
  • mIL-8RH antibody

Protein level used designations for CXCR2

C-X-C chemokine receptor type 2 , interleukin 8 receptor beta , interleukin-8 receptor CXCR2 , CXC-R2 , CXCR-2 , CXCR2 gene for IL8 receptor type B , GRO/MGSA receptor , IL-8 receptor type 2 , IL-8R B , chemokine (CXC) receptor 2 , high affinity interleukin-8 receptor B , interleukin 8 receptor B , interleukin 8 receptor type 2 , interleukin 8 receptor, beta , interleukin-8 receptor type B , chemokine receptor CXCR2 , interleukin 8 receptor, alpha , IL-8 receptor alpha chain , chemokine (C-X-C) receptor 2 , IL-8 receptor , High affinity interleukin-8 receptor B , interleukin-8 receptor, beta

GENE ID SPECIES
100379569 Cavia porcellus
3579 Homo sapiens
782719 Bos taurus
12765 Mus musculus
100328627 Oryctolagus cuniculus
29385 Rattus norvegicus
700407 Macaca mulatta
470644 Pan troglodytes
478905 Canis lupus familiaris
Selected quality suppliers for anti-CXCR2 (CXCR2) Antibodies
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