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The protein encoded by CXCR2 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR2 Kits (33) and CXCR2 Proteins (8) and many more products for this protein.
Showing 10 out of 258 products:
Human Monoclonal CXCR2 Primary Antibody for FACS, IHC - ABIN4899080
Keane, Donnelly, Belperio, Goodman, Dy, Burdick, Fishbein, Strieter: Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome. in Journal of immunology (Baltimore, Md. : 1950) 2002
Show all 30 references for ABIN4899080
Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS, Neut - ABIN4899087
Bi, Zhou, Yang, Wang, Zhang, Wang, Wu, Han, Song, Tan, Du, Yang, Zhou, Cui, Zhou, Yan, Zhang, Guo, Wang, Liu, Yang: IL-17A produced by neutrophils protects against pneumonic plague through orchestrating IFN-γ-activated macrophage programming. in Journal of immunology (Baltimore, Md. : 1950) 2014
Show all 18 references for ABIN4899087
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895453
Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 6 references for ABIN4895453
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895449
Mihara, Smit, Krajnc-Franken, Gossen, Rooseboom, Dokter: Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice. in European journal of immunology 2005
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Human Polyclonal CXCR2 Primary Antibody for EIA, IHC (fro) - ABIN492888
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
Show all 4 references for ABIN492888
Mouse (Murine) Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895472
Citro, Valle, Cantarelli, Mercalli, Pellegrini, Liberati, Daffonchio, Kastsiuchenka, Ruffini, Battaglia, Allegretti, Piemonti: CXCR1/2 inhibition blocks and reverses type 1 diabetes in mice. in Diabetes 2015
Show all 3 references for ABIN4895472
Human Polyclonal CXCR2 Primary Antibody for FACS, WB - ABIN1742104
Pagé, Robitaille, Pouysségur, Richard: Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. in The Journal of biological chemistry 2002
Show all 2 references for ABIN1742104
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN319852
Petering, Götze, Kimmig, Smolarski, Kapp, Elsner: The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils. in Blood 1999
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN4895445
Pokkali, Das, R: Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. in Cytokine 2008
Human Polyclonal CXCR2 Primary Antibody for WB - ABIN2777085
Gauvreau, Boulet, Cockcroft, Baatjes, Cote, Deschesnes, Davis, Strinich, Howie, Duong, Watson, Renzi, OByrne: Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. in American journal of respiratory and critical care medicine 2008
this study shows that downregulation of CD182 (show CXCR3 Antibodies) after stimulation with IL-8 (show IL8 Antibodies) is more pronounced in adults than in neonates, whereas fMLP (show FPR1 Antibodies) induces changes in receptor expression that are of the same magnitude in neutrophils from neonates as from adults
findings present that miR (show MLXIP Antibodies)-940 acts as a pivotal adaptor of CXCR2 and its transcription downregulated CXCR2 expression to decrease HCC (show FAM126A Antibodies) invasion and migration in vitro.
Our findings suggest that CXCL3 (show CXCL3 Antibodies) and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.
Data suggest that neutrophil-activating peptide 2 (NAP-2 (show PPBP Antibodies)) secreted by NK cells can bind to CXC Chemokine Receptor (show CXCR4 Antibodies) 2 (CXCR2) on mesenchymal stem cells (MSCs) leading to stimulation of its recruitment.
High CXCR2 expression is associated with pancreatic cancer.
These data provide rationale that targeting CXCR1 (show CXCR1 Antibodies)/2 with small molecule inhibitors may enhance chemotherapeutic efficacy for the treatment of gastric cancer.
Letter: cold temperatures up regulate CXCR2 ligand Il8 (show IL8 Antibodies) in microvascular endothelial cells which may contribute to neutrophil recruitment and inflammation in skin from patients with livedo vasculopathy with winter ulcerations.
The results showed that the expression of N-Ac-PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP.
The results of this study show that the CXCR2 rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Antibodies) genes.
These studies provide direct evidence linking the activation of IL8 (show IL8 Antibodies), DNA demethylation and the induction of the OA process with important therapeutic implications therein for patients with this debilitating disease.
Results also demonstrated that in CXCR2 (show CXCR1 Antibodies), genotypes BC, CC and FF were probably relevant with mastitis and the genotypes AA, AB and EE may have better milk quality.
CXCR2/CXCL1 (show CXCL1 Antibodies) axis promotes granulocytic myeloid-derived suppressor cells recruitment and facilitates arginase I (show ARG1 Antibodies) expression and activity of these cells at maternal-fetal interface
CXCR2 plays a critical role in particle-induced osteolysis.
This study demonstated that endothelial CXCR2 play essential roles in cerebral endothelial activation and subsequent leukocyte recruitment during neuroinflammation.
Studied DC-specific TLR4 (show TLR4 Antibodies) signaling on host defense against intra-abdominal polymicrobial sepsis; found TLR4 (show TLR4 Antibodies) deletion on DCs was associated with lower levels of IL-10 (show IL10 Antibodies), higher PMN (show TBCE Antibodies) accumulation in the peritoneal cavity, and higher expression of CXCR2.
CXCL1 (show CXCL1 Antibodies) monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 activation
p53 (show TP53 Antibodies)-mediated induction of PAI-1 (show SERPINE1 Antibodies) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1 (show CXCL1 Antibodies), CXCL2 (show CXCL2 Antibodies), and CXCR2.
Suggest chemotherapy-specific differential regulation of CXCR2 ligands, stem cell-like and mesenchymal phenotypes, and enhanced metastasis in drug-resistant cells and targeting CXCR2 signaling, may help circumvent therapy resistance in breast cancer.
Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Antibodies) via TLR2 (show TLR2 Antibodies) and directly synergizes with this chemokine (show CCL1 Antibodies) via CXCR2 and formyl peptide receptor 2 (show FPR2 Antibodies) to recruit neutrophils.
Blockade of CXCR2 during Hpb challenge infection reproduced the delayed wound repair observed in helminth infected Aid-/- and Fcrg (show FCER1G Antibodies)-/- mice.
CXCR2 and CX3CR1 (show CX3CR1 Antibodies) differentially regulate EPC (show TCF21 Antibodies) functional responses during atheroregression
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
C-X-C chemokine receptor type 2
, interleukin 8 receptor beta
, interleukin-8 receptor CXCR2
, CXCR2 gene for IL8 receptor type B
, GRO/MGSA receptor
, IL-8 receptor type 2
, IL-8R B
, chemokine (CXC) receptor 2
, high affinity interleukin-8 receptor B
, interleukin 8 receptor B
, interleukin 8 receptor type 2
, interleukin 8 receptor, beta
, interleukin-8 receptor type B
, chemokine receptor CXCR2
, interleukin 8 receptor, alpha
, IL-8 receptor alpha chain
, chemokine (C-X-C) receptor 2
, IL-8 receptor
, High affinity interleukin-8 receptor B
, interleukin-8 receptor, beta