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The protein encoded by CXCR2 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR2 Kits (35) and CXCR2 Proteins (7) and many more products for this protein.
Showing 10 out of 237 products:
Human Polyclonal CXCR2 Primary Antibody for EIA, IHC (fro) - ABIN492890
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
Show all 4 references for ABIN492890
Human Polyclonal CXCR2 Primary Antibody for EIA, IHC (fro) - ABIN492888
Segerer: The role of chemokines and chemokine receptors in progressive renal diseases. in American journal of kidney diseases : the official journal of the National Kidney Foundation 2003
Show all 4 references for ABIN492888
Human Polyclonal CXCR2 Primary Antibody for FACS, WB - ABIN1742104
Pagé, Robitaille, Pouysségur, Richard: Induction of hypoxia-inducible factor-1alpha by transcriptional and translational mechanisms. in The Journal of biological chemistry 2002
Show all 2 references for ABIN1742104
Human Polyclonal CXCR2 Primary Antibody for WB - ABIN2777085
Gauvreau, Boulet, Cockcroft, Baatjes, Cote, Deschesnes, Davis, Strinich, Howie, Duong, Watson, Renzi, OByrne: Antisense therapy against CCR3 and the common beta chain attenuates allergen-induced eosinophilic responses. in American journal of respiratory and critical care medicine 2008
Human Monoclonal CXCR2 Primary Antibody for FACS - ABIN319852
Petering, Götze, Kimmig, Smolarski, Kapp, Elsner: The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils. in Blood 1999
Human Polyclonal CXCR2 Primary Antibody for IF (cc), IF (p) - ABIN732218
Goetzenich, Kraemer, Rossaint, Bleilevens, Dollo, Siry, Rajabi-Alampour, Beckers, Soppert, Lue, Rex, Bernhagen, Stoppe: The role of macrophage migration inhibitory factor in anesthetic-induced myocardial preconditioning. in PLoS ONE 2014
The results of this study show that the CXCR2 rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Antibodies) genes.
These studies provide direct evidence linking the activation of IL8 (show IL8 Antibodies), DNA demethylation and the induction of the OA process with important therapeutic implications therein for patients with this debilitating disease.
Studied the expression of CXCL8 (show IL8 Antibodies)-CXCR1 (show CXCR1 Antibodies)/2 pathway, its impact on cell proliferation and cytokine expression in human colorectal carcinoma HCT116 cells.
Inhibition of IL-8 (show IL8 Antibodies) signalling can enhance response in platinum sensitive and resistant high grade serous ovarian carcinoma.
CXCR2 expression is enriched in human atherosclerotic coronary artery.
CXCR2-CXCL1 (show CXCL1 Antibodies) axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma
we found the mRNA level of NF-kappaB (show NFKB1 Antibodies) and IL-8 (show IL8 Antibodies) was higher in gastric ulcer patients, especially in patients with H.pylori-positive gastric ulcer.
Data show that trefoil factor-3 (TFF3 (show TFF3 Antibodies)) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 Antibodies))/IL-8 (show IL8 Antibodies) receptor (show CXCR1 Antibodies) CXCR2.
G31P blockage of CXCR1 (show CXCR1 Antibodies) and CXCR2 can inhibit human lung cancer cell growth and metastasis
Study shows that CXCL5 (show CXCL5 Antibodies) expression is elevated in positive correlation to bladder cancer grade and promotes cell migration and invasion via binding to its receptor CXCR2.
Results also demonstrated that in CXCR2 (show CXCR1 Antibodies), genotypes BC, CC and FF were probably relevant with mastitis and the genotypes AA, AB and EE may have better milk quality.
This study demonstated that endothelial CXCR2 play essential roles in cerebral endothelial activation and subsequent leukocyte recruitment during neuroinflammation.
Studied DC-specific TLR4 (show TLR4 Antibodies) signaling on host defense against intra-abdominal polymicrobial sepsis; found TLR4 (show TLR4 Antibodies) deletion on DCs was associated with lower levels of IL-10 (show IL10 Antibodies), higher PMN (show TBCE Antibodies) accumulation in the peritoneal cavity, and higher expression of CXCR2.
CXCL1 (show CXCL1 Antibodies) monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 activation
p53 (show TP53 Antibodies)-mediated induction of PAI-1 (show SERPINE1 Antibodies) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1 (show CXCL1 Antibodies), CXCL2 (show CXCL2 Antibodies), and CXCR2.
Suggest chemotherapy-specific differential regulation of CXCR2 ligands, stem cell-like and mesenchymal phenotypes, and enhanced metastasis in drug-resistant cells and targeting CXCR2 signaling, may help circumvent therapy resistance in breast cancer.
Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Antibodies) via TLR2 (show TLR2 Antibodies) and directly synergizes with this chemokine (show CCL1 Antibodies) via CXCR2 and formyl peptide receptor 2 (show FPR2 Antibodies) to recruit neutrophils.
Blockade of CXCR2 during Hpb challenge infection reproduced the delayed wound repair observed in helminth infected Aid-/- and Fcrg (show FCER1G Antibodies)-/- mice.
CXCR2 and CX3CR1 (show CX3CR1 Antibodies) differentially regulate EPC (show TCF21 Antibodies) functional responses during atheroregression
CXCr2 regulates the hepatic proliferative response and subsequent liver regeneration.
Data revealed a critical role of a PDZ (show INADL Antibodies)-based CXCR2 macromolecular complex in EPC (show TCF21 Antibodies) homing and angiogenesis.
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.
C-X-C chemokine receptor type 2
, interleukin 8 receptor beta
, interleukin-8 receptor CXCR2
, CXCR2 gene for IL8 receptor type B
, GRO/MGSA receptor
, IL-8 receptor type 2
, IL-8R B
, chemokine (CXC) receptor 2
, high affinity interleukin-8 receptor B
, interleukin 8 receptor B
, interleukin 8 receptor type 2
, interleukin 8 receptor, beta
, interleukin-8 receptor type B
, chemokine receptor CXCR2
, interleukin 8 receptor, alpha
, IL-8 receptor alpha chain
, chemokine (C-X-C) receptor 2
, IL-8 receptor
, High affinity interleukin-8 receptor B
, interleukin-8 receptor, beta