You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Chromobox Homolog 5 (CBX5) Antibodies

CBX5 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. Additionally we are shipping CBX5 Proteins (8) and CBX5 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CBX5 12419 Q61686
CBX5 23468 P45973
CBX5 300266  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top anti-CBX5 Antibodies at

Showing 10 out of 237 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB CBX5 Antibody (Center) (ABIN657701) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the CBX5 antibody detected the CBX5 protein (arrow). 400 μL Log in to see 10 to 11 Days
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-CBX5 Antibody Titration: 1.25ug/mlPositive Control: Human brain 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB ABIN185491 (0.03µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185491 (2.5µg/ml) staining of paraffin embedded Human Uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 4 to 5 Days
Dog Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/A549/K562 cells, using CBX5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to CBX5 on HeLa cell (antibody concentration 10 µg/mL).  CBX5 monoclonal antibody (M01), clone 1E11-3A10 Western Blot analysis of CBX5 expression in HeLa NE. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using HP1 alpha (Phospho-Ser92) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated ICC, IHC, WB Western blot detection of CBX5 in MCF7, 293T, HelaNE, 3T3, C6, COS7 and Mouse brain lysates and using CBX5 antibody (1: 1000 diluted).  Predicted band size: 22 kDa.  Observed band size: 22 kDa Immunocytochemistry stain of Hela using CBX5 antibody (1: 300). 100 μL Log in to see 8 to 9 Days
Dog Goat Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days

CBX5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , ,
, ,
, , , , , , , , , , , , , , , , , , ,
Human , , , ,
, , ,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) ,
, ,
, , , , , , , , , , ,

Top referenced anti-CBX5 Antibodies

  1. Human Monoclonal CBX5 Primary Antibody for IF, WB - ABIN393505 : Nozawa, Nagao, Masuda, Iwasaki, Hirota, Nozaki, Kimura, Obuse: Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. in Nature cell biology 2010 (PubMed)
    Show all 5 references for ABIN393505

  2. Human Polyclonal CBX5 Primary Antibody for WB - ABIN657701 : Emelyanov, Konev, Vershilova, Fyodorov: Protein complex of Drosophila ATRX/XNP and HP1a is required for the formation of pericentric beta-heterochromatin in vivo. in The Journal of biological chemistry 2010 (PubMed)
    Show all 3 references for ABIN657701

  3. Dog (Canine) Polyclonal CBX5 Primary Antibody for IHC (p), WB - ABIN374617 : Rohr, Lecestre, Chasserot-Golaz, Marban, Avram, Aunis, Leid, Schaeffer: Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells. in Journal of virology 2003 (PubMed)

  4. Human Polyclonal CBX5 Primary Antibody for ELISA, WB - ABIN1533736 : Minc, Allory, Worman, Courvalin, Buendia: Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells. in Chromosoma 1999 (PubMed)

  5. Cow (Bovine) Polyclonal CBX5 Primary Antibody for IHC, WB - ABIN2779672 : Fujita, Watanabe, Ichimura, Tsuruzoe, Shinkai, Tachibana, Chiba, Nakao: Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against CBX5 Interaction Partners

Mouse (Murine) Chromobox Homolog 5 (CBX5) interaction partners

  1. HP1-alpha oligomerization is critical to the maintenance of heterochromatin and the tunable dynamics of this HP1 isoform.

  2. demonstrate an actin-driven differential modulation of core histone H2B and heterochromatin HP1alpha protein dynamics with chromatin

  3. the molecular behavior of HP1alpha throughout the cell cycle

  4. There is a functional link between prelamin A, HP1alpha, chromatin remodeling, DNA repair, and early senescence in Zmpste24 (show Zmpste24 Antibodies)-deficient mice, suggesting a potential therapeutic strategy for laminopathy-based premature aging via the intervention of HP1alpha.

  5. the TIF1beta (show TRIM28 Antibodies)-HP1 system functions as a critical repressive machinery that targets genes not normally activated in the hematopoietic compartment, thereby maintaining the transcriptional signature specific to HSCs.

  6. HP1 mobility in apoptotic cells appeared to be unique.

  7. Elimination of HP1alpha by siRNA interfered with centromere relocation from heterochromatin surrounding NPBs to pro-chromocenters at the two-cell stage but did not affect preimplantation develoment to the blastocyst stage.

  8. Depletion of Senp7 (show SENP7 Antibodies) delocalizes HP1 alpha from pericentric heterochromatin without affecting H3K9me3 levels.

  9. The interplay between MU2 (show AP2M1 Antibodies) and HP1a is dynamic and may be different in euchromatin and heterochromatin during DNA break recognition and repair.

  10. KAP1 (show TRIM28 Antibodies) and HP1 tether activation-induced cytidine deaminase (show AICDA Antibodies) (AID) to H3K9me3 residues at the donor switch region, thus linking AID to epigenetic modifications during class switch recombination.

Human Chromobox Homolog 5 (CBX5) interaction partners

  1. We demonstrate that an hnRNPA1 (show HNRNPA1 Antibodies) and CBX5 bi-directional core promoter fragment does not comprise intrinsic capacity for specific CBX5 down-regulation in metastatic cells

  2. HP1alpha plays an important role in the differentiation and angiogenic function of Endothelial Progenitor Cells.

  3. Jra recruits the HP1a (show TFF1 Antibodies)/KDM4A (show KDM4A Antibodies) complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation

  4. SET interacts with the Kruppel-associated box (KRAB)-associated co-repressor KAP1 (show CDKN3 Antibodies), and its overexpression results in the sustained retention of KAP1 (show CDKN3 Antibodies) and Heterochromatin protein 1 (HP1 (show DEFA1 Antibodies)) on chromatin

  5. HP1 (show DEFA1 Antibodies) regulates this gene's alternative splicing in a methylation-dependent manner by recruiting splicing factors to its methylated form.

  6. PIP5K1A (show PIP5K1A Antibodies) modulates ribosomal RNA gene silencing through its interaction with histone H3 (show HIST3H3 Antibodies) lysine 9 trimethylation and heterochromatin protein HP1-alpha.

  7. Paternal heterochromatin formation in human embryos is H3K9/HP1 (show DEFA1 Antibodies) directed and primed by sperm-derived histone modifications.

  8. a considerable number of alternative splicing events could have a chromatin-dependent regulation involving the association of HP1alpha and CTCF (show CTCF Antibodies) near regulated exons.

  9. Identify a nuclear localization signal within the 462-494 amino acid region of TRIM28 (show TRIM28 Antibodies) that overlaps with its HP1 (show DEFA1 Antibodies) binding site. GST (show SLCO6A1 Antibodies)-pulldown experiments revealed the interaction of the arginine-rich TRIM28 (show TRIM28 Antibodies) NLS (show ALDH1A2 Antibodies) with various importin alpha (show KPNA4 Antibodies) subtypes.

  10. Data show that RRP1B regulates metastasis associated gene expression by interacting with the transcriptional corepressors TRIM28 (show TRIM28 Antibodies) and HP1a (show TFF1 Antibodies), which act by recruiting chromatin-modifying enzymes.

CBX5 Antigen Profile

Protein Summary

This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with CBX5

  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5) antibody
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5) antibody
  • chromobox homolog 5 (cbx5) antibody
  • chromobox 5 (Cbx5) antibody
  • chromobox homolog 5 (CBX5) antibody
  • chromobox homolog 5 (Cbx5) antibody
  • 2610029O15Rik antibody
  • C75991 antibody
  • cbx5 antibody
  • HP1 antibody
  • HP1A antibody
  • Hp1alpha antibody
  • id:ibd2026 antibody
  • MGC64354 antibody
  • wu:fc63e02 antibody
  • wu:fe47g12 antibody
  • wu:fi03h05 antibody
  • zgc:158601 antibody

Protein level used designations for CBX5

chromobox protein homolog 5 , fc63e02 , chromobox homolog 5 (HP1 alpha homolog, Drosophila) , chromobox-like protein 5 (HP1 alpha homolog, Drosophila) , HP1 alpha , chromobox homolog 5 , heterochromatin protein 1 alpha , heterochromatin protein 1 homolog alpha , mHP1(alpha) , HP1 alpha homolog , HP1-ALPHA , HP1Hs alpha , antigen p25 , heterochromatin protein 1-alpha , chromobox-like protein 5 , chromobox homolog 5 tv3

563396 Danio rerio
467011 Pan troglodytes
100307036 Ovis aries
380557 Xenopus laevis
394502 Xenopus (Silurana) tropicalis
12419 Mus musculus
23468 Homo sapiens
477593 Canis lupus familiaris
538885 Bos taurus
300266 Rattus norvegicus
100519426 Sus scrofa
Selected quality suppliers for anti-CBX5 (CBX5) Antibodies
Did you look for something else?