CBX5 Products
(Chromobox Homolog 5 (CBX5))
Categories
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
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Featured CBX5 Categories
CBX5 Antibodies
High quality antibodies with extensive validation data.
CBX5 ELISA Kits
Reliable ELISA kits for a wide range of species.
CBX5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CBX5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, FACS
Validations
- (8)
Cat. No.
ABIN185491
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (8)
Cat. No.
ABIN5542711
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (5)
Cat. No.
ABIN565097
Quantity
100 μg
Datasheet
Datasheet
Recommended CBX5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648334
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6951753
Quantity
96 tests
Datasheet
Datasheet
Recommended CBX5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122366
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348213
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7505415
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CBX5 products
: "Arginine methylation expands the regulatory mechanisms and extends the genomic landscape under E2F control." in: Science advances, Vol. 5, Issue 6, pp. eaaw4640, (2019) (PubMed).: "Isolation of In Vivo SUMOylated Chromatin-Bound Proteins." in: Methods in molecular biology (Clifton, N.J.), Vol. 1475, pp. 205-16, (2016) (PubMed).
: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).
: "SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase." in: Cell reports, Vol. 13, Issue 6, pp. 1183-93, (2015) (PubMed).
: "Structural maintenance of chromosomes flexible hinge domain containing 1 (SMCHD1) promotes non-homologous end joining and inhibits homologous recombination repair upon DNA damage." in: The Journal of biological chemistry, Vol. 289, Issue 49, pp. 34024-32, (2014) (PubMed).
: "Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e84358, (2014) (PubMed).
: "Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 43, pp. 17466-71, (2012) (PubMed).
: "The Heterochromatin Protein 1 family." in: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).
: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." in: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).
: "Transcription factor YY1 associates with pericentromeric gamma-satellite DNA in cycling but not in quiescent (G0) cells." in: Nucleic acids research, Vol. 32, Issue 14, pp. 4390-9, (2004) (PubMed).
Synonyms and alternative names related to CBX5
chromobox 5 (CBX5), chromobox homolog 5 (HP1 alpha homolog, Drosophila) (cbx5), chromobox 5 (Cbx5), chromobox 5 S homeolog (cbx5.S), chromobox 5 (cbx5), 2610029O15Rik, C75991, CBX5, cbx5, HP1, HP1A, Hp1a, Hp1alpha, id:ibd2026, MGC64354, wu:fc63e02, wu:fe47g12, wu:fi03h05, zgc:158601Protein level used designations for CBX5
- HP1 alpha homolog
- HP1-ALPHA
- HP1Hs alpha
- antigen p25
- chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- chromobox protein homolog 5
- heterochromatin protein 1 homolog alpha
- heterochromatin protein 1-alpha
- fc63e02
- chromobox-like protein 5
- chromobox-like protein 5 (HP1 alpha homolog, Drosophila)
- HP1 alpha
- chromobox homolog 5
- heterochromatin protein 1 alpha
- mHP1(alpha)
- chromobox homolog 5 tv3
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