You are viewing an incomplete version of our website. Please click to reload the website as full version.

Complement Component 5a Receptor 1 Proteins (C5AR1)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. Additionally we are shipping C5AR1 Antibodies (255) and C5AR1 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C5AR1 12273  
C5AR1 728 P21730
Rat C5AR1 C5AR1 113959 P97520
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online

Top C5AR1 Proteins at

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

C5AR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,

Top referenced C5AR1 Proteins

  1. Human C5AR1 Protein expressed in Wheat germ - ABIN1347567 : Spaan, Vrieling, Wallet, Badiou, Reyes-Robles, Ohneck, Benito, de Haas, Day, Jennings, Lina, Vandenesch, van Kessel, Torres, van Strijp, Henry: The staphylococcal toxins ?-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors. in Nature communications 2014 (PubMed)

More Proteins for Complement Component 5a Receptor 1 (C5AR1) Interaction Partners

Mouse (Murine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. CYP4F18 (show CYP4F3 Proteins)-deficient neutrophils exhibit increased chemotaxis to complement component C5a.

  2. showed that C3a (show C3 Proteins) receptor/C5a receptor-deficient mice developed much less severe uveitis than did control mice using all retinal examination methods

  3. Knockout of the C5aR1 attenuated the effect of beta1-AR in the heart, suggesting an association between the beta1-AR and C5aR1, although further investigation is required to determine if this is a direct or causal association

  4. Data (including data from studies in knockout mice) suggest that C5aR/C5aR (complement C5a/anaphylatoxin (show C5 Proteins) C5a Receptor) signaling pathway is involved in neurocognitive injury in uninfected pups induced by malaria in pregnancy.

  5. Data indicate that C5ar1 activation plays a role in seizure initiation and severity, as well as neuronal degeneration following status epilepticus.

  6. identifies a key role for C5aR signaling in astrocyte proliferation and glial scarring during the chronic phase of Spinal Cord Injury.

  7. Porphyromonas gingivalis induced C5aR-TLR2 crosstalk leads to MyD88 degradation.

  8. Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 (show DPP4 Proteins) define distinct hematopoietic lineages of dendritic cells.

  9. Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice.

  10. our findings suggest that C5aR1 expression in mice is largely restricted to cells of the myeloid lineage

Human Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. that C5aR stimulates cell invasion and migration via ERK1/2-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells

  2. Inhibition of C5aR1 leads to a significant reduction of CD66b and CD11b (show ITGAM Proteins) expression indicating a lower neutrophil activation status and block of granule exocytosis.

  3. that rs10853784 of C5aR1 gene are associated with coronary artery disease in Han population of China

  4. 96.7% of the metastatic RCCs had C5aR expression, vs. 50.5% of the non-metastatic ones. C5a triggered ERK- and PI3Kdependent invasion of the C5aR-expressing renal carcinoma cells. The C5a-C5aR axis plays a crucial role in renal carcinoma cell invasion.

  5. These results illustrate the novel activity of the C5a-C5aR axis that promotes human NPC (show NPC1 Proteins) cell proliferation through PCAFmediated STAT3 (show STAT3 Proteins) acetylation.

  6. C5a/C5aR1 signalling plays a key role in disrupting blood-brain barrier integrity through different cascades including NF-KappaB translocation leading to altered tight junction proteins, Claudin-5 and ZO-1, and actin reorganization in the lupus setting

  7. ). Low frequency of the C5aR 450 CT genotype, which apparently is a feature of certain kidney diseases, appears to be associated with good graft outcome in kidney transplantation.

  8. Observed a positive correlation between the expression of anaphylatoxin-receptors C3aR (show C3AR1 Proteins) and C5aR with platelet activation in patients with coronary artery disease.

  9. C5AR1 SNP -1330T/G may serve as a useful pharmacodynamic predictor of nonsedating H1-antihistamine efficacy in chronic spontaneous urticaria (CSU), and -1330T alleles may be taken as a risk factor for CSU.

  10. Porphyromonas gingivalis induces C5aR-TLR2 coassociation in neutrophils.

Cow (Bovine) Complement Component 5a Receptor 1 (C5AR1) interaction partners

  1. Studies provide information regarding distinct structural and functional features that may contribute to the unique pharmacological properties of bovine C5aR.

C5AR1 Protein Profile

Protein Summary

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Gene names and symbols associated with C5AR1

  • complement component 5a receptor 1 (C5AR1)
  • complement component 5a receptor 1 (c5ar1)
  • C5a anaphylatoxin chemotactic receptor-like (LOC100352978)
  • complement component 5a receptor 1 (C5ar1)
  • C5A protein
  • C5AR protein
  • C5AR1 protein
  • C5r1 protein
  • CD88 protein
  • D7Msu1 protein
  • GPR77 protein

Protein level used designations for C5AR1

complement component 5a receptor 1 , C5a anaphylatoxin receptor , G protein-coupled receptor 77 , C5a anaphylatoxin chemotactic receptor 1 , C5a ligand , C5a-R , complement component 5, receptor 1 , complement component 5 receptor 1 , C5aR , complement C5a receptor , anaphylatoxin C5a receptor , complement component 5 receptor 1 (C5a ligand) , C5a anaphylatoxin chemotactic receptor

397287 Sus scrofa
430484 Gallus gallus
100379958 Xenopus (Silurana) tropicalis
100589337 Nomascus leucogenys
100352978 Oryctolagus cuniculus
12273 Mus musculus
728 Homo sapiens
113959 Rattus norvegicus
100135489 Cavia porcellus
442974 Canis lupus familiaris
718056 Macaca mulatta
468931 Pan troglodytes
100048955 Sus scrofa
493645 Bos taurus
Selected quality suppliers for C5AR1 Proteins (C5AR1)
Did you look for something else?