C5AR1 Protein
-
- Target See all C5AR1 Proteins
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Protein Type
- Synthetic
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purpose
- Human C5AR1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product C5AR1 Protein
-
Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) protein (GST tag)
C5AR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) (AA 241-350) protein (GST tag)C5AR1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) protein (Myc-DYKDDDDK Tag)C5AR1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- Application Notes
-
- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
-
Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
-
- Target
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Alternative Name
- C5AR1 (C5AR1 Products)
- Synonyms
- C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein
- Background
-
C5A, C5AR, C5R1, CD88
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).[UniProtKB/Swiss-Prot Function] - Molecular Weight
- The human full length C5AR1 protein has a MW of 39.3 kDa
- UniProt
- P21730
- Pathways
- Complement System
-
