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Contactin Associated Protein-Like 2 (CNTNAP2) ELISA Kits

CNTNAP2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. Additionally we are shipping CNTNAP2 Antibodies (56) and CNTNAP2 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CNTNAP2 CNTNAP2 362355  
CNTNAP2 26047 Q9UHC6
Anti-Mouse CNTNAP2 CNTNAP2 66797 Q9CPW0
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for CNTNAP2 Interaction Partners

Human Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. rs7794745 in the CNTNAP2 gene was associated with autistic spectrum disorder in Brazilian patients.

  2. we could not detect any significant association with the CNTNAP2 gene and high functioning autism

  3. CNTNAP2 is transcriptionally regulated by FOXP2 (show FOXP2 ELISA Kits).

  4. Structurally, CASPR2 is highly glycosylated and has an overall compact architecture. CASPR2 associates with micromolar affinity with CNTN1 (show CNTN1 ELISA Kits) but, under the same conditions, it does not interact with any of the other members of the contactin family.

  5. Results indicate that the CNTNAP2 gene may confer vulnerability to speech sound disorder

  6. The study of zebrafish mutants of the ASD (show ARSD ELISA Kits) risk gene, CNTNAP2, and its differential responses to psychoactive agents reveals the strength of this approach to identify molecular mechanisms

  7. Deletions within CNTNAP2 were found in two children with CAS (show CSE1L ELISA Kits) but not in any of the children with SLI (show SHC2 ELISA Kits). These findings suggest that genetic variation within CNTNAP2 may be related to speech production deficits.

  8. A genetic and functional characterization study of the CNTNAP2 promoter in autism spectrum disorders

  9. A new male-specific association with aging is reported for a CNV in the CNTNAP2 gene. esv11910 ins (show INS ELISA Kits) allele was inversely associated with healthy aging in men.

  10. We find no evidence for statistically significant association of rare heterozygous mutations in any of the CNTN (show CNTN1 ELISA Kits) or CNTNAP (show CNTNAP1 ELISA Kits) genes, including CNTNAP2, placing marked limits on the scale of their plausible contribution to risk.

Mouse (Murine) Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. After middle cerebral artery occlusion mice demonstrate profoundly impaired socially evoked USVs. In addition, there is suppression of the language-associated transcription factor,contactin-associated protein 2 (Cntnap2).

  2. Olfaction-based behavioral tests revealed that mice lacking Caspr2 exhibit abnormal response to sensory stimuli and lack preference for novel odors.

  3. Mice with the Cntnap2 genetic mutation showed a dissociation of auditory-processing abilities

  4. Study reports behavioral characterization of mouse models of autism with null mutation in Cntnap2 gene. It shows hyperactivity, mild gait phenotype and reduced vocalizations among others.

  5. new dendritic spines in mice lacking CNTNAP2 were formed at normal rates, but failed to stabilize. Notably, rates of spine elimination were unaltered, suggesting a specific role for CNTNAP2 in stabilizing new synaptic circuitry

  6. Cntnap2 deletion selectively impairs perisomatic hippocampal inhibition while sparing excitation provide additional support for synaptic dysfunction as a common mechanism underlying autism spectrum disorders

  7. The CASPR2/MUPP1 (show MPDZ ELISA Kits) receptor complex co-localized with GPR37 (show GPR37 ELISA Kits) in hippocampal neurons.

  8. Interaction proteomics revealed the interactors of Caspr2, including CNTN2, KCNAs, members of the ADAM family (ADAM22, ADAM23 and ADAM11), members of LGI family and MAGUKs (DLGs and MPPs).

  9. CNTNAP2 has a role in the correct trafficking of GluA1 (show GRIA1 ELISA Kits) AMPA (show GRIA3 ELISA Kits)-type glutamate (show GRIN1 ELISA Kits) receptors

  10. Caspr2 is required for paranodal clustering of Kv1 (show KCNA5 ELISA Kits) channels in the absence of Caspr (show CNTNAP1 ELISA Kits). Absence of both Caspr (show CNTNAP1 ELISA Kits) and Caspr2 results in the widening of the nodes of Ranvier.

CNTNAP2 Antigen Profile

Antigen Summary

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.

Gene names and symbols associated with CNTNAP2

  • contactin associated protein-like 2 (CNTNAP2) antibody
  • contactin associated protein-like 2 (cntnap2) antibody
  • contactin associated protein-like 2 (Cntnap2) antibody
  • 5430425M22Rik antibody
  • AUTS15 antibody
  • CASPR antibody
  • Caspr2 antibody
  • CDFE antibody
  • MGC145769 antibody
  • MGC147944 antibody
  • MGC147981 antibody
  • mKIAA0868 antibody
  • NRXN4 antibody
  • PTHSL1 antibody

Protein level used designations for CNTNAP2

cell recognition molecule Caspr2 , contactin associated protein-like 2 , novel protein similar to H.sapiens contactin associated protein , contactin associated protein 2 , contactin-associated protein-like 2 , contactin-associated protein-like 2-like , homolog of Drosophila neurexin IV

463819 Pan troglodytes
516395 Bos taurus
563345 Danio rerio
574172 Macaca mulatta
780189 Xenopus (Silurana) tropicalis
100174321 Pongo abelii
362355 Rattus norvegicus
100013863 Monodelphis domestica
100060296 Equus caballus
100073864 Ornithorhynchus anatinus
100223892 Taeniopygia guttata
100354524 Oryctolagus cuniculus
100397041 Callithrix jacchus
100607262 Nomascus leucogenys
26047 Homo sapiens
66797 Mus musculus
500105 Rattus norvegicus
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