Creatine Kinase, Brain Proteins (CKB)

The protein encoded by CKB is a cytoplasmic enzyme involved in energy homeostasis. Additionally we are shipping Creatine Kinase, Brain Antibodies (227) and Creatine Kinase, Brain Kits (50) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CKB 29367 O54783
CKB 1152 P12277
CKB 12709 Q04447
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Top Creatine Kinase, Brain Proteins at

Showing 10 out of 33 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 20 to 21 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Human Un-conjugated   100 μg Log in to see 6 to 8 Days
HOST_Escherichia coli (E. coli) Dog His tag 100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 15 to 18 Days

CKB Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,

Human , , , , , , ,
, ,
Mouse (Murine) , ,

Top referenced Creatine Kinase, Brain Proteins

  1. Human CKB Protein expressed in Escherichia coli (E. coli) - ABIN667148 : Chang, Ha, Oerlemans, Lee, Lee, Ryu, Kim, Lee, Kim, Choi, Kim, Shin, Pak, Tanaka, Wieringa, Lee, Kim: Brain-type creatine kinase has a crucial role in osteoclast-mediated bone resorption. in Nature medicine 2008 (PubMed)
    Show all 2 references for 667148

  2. Human CKB Protein expressed in Baculovirus infected Insect Cells - ABIN2006177 : Mariman, Schepens, Wieringa: Complete nucleotide sequence of the human creatine kinase B gene. in Nucleic acids research 1989 (PubMed)

More Proteins for Creatine Kinase, Brain (CKB) Interaction Partners

Rabbit Creatine Kinase, Brain (CKB) interaction partners

  1. The effect of Zn(2+) on the folding and aggregation of brain creatine kinase (CK-BB), was studied.

  2. report the identity of a 45 kDa imidazoline binding protein to be brain creatine kinase and this enzyme possesses an I2 binding site; findings will undoubtedly contribute to greater understanding of and development of imidazoline therapeutic drugs.

Human Creatine Kinase, Brain (CKB) interaction partners

  1. SRC (show SRC Proteins), LYN (show LYN Proteins) and CKB (show CHKB Proteins) expression or DNA methylation (show HELLS Proteins) could be useful markers for predicting tumor progression.

  2. CK-B catalytic activity also helps in the formation of protrusive ruffle structures which are actin-dependent and abundant on the surface of both unstimulated and LPS (show IRF6 Proteins)-activated macrophages.

  3. increased serum Ckbb reflects failure of osteoclasts or suppression of osteoclasts in children with osteogenesis imperfecta (show COL1A2 Proteins) during neridronate treatment

  4. We found that most patients with macular telangiectasia-2 possess retinal autoantibodies, the most prevalent of which were directed against AGL (show AGL Proteins), RBP3 (show E2F1 Proteins), and CK-B.

  5. study found promoter SNPs of CKB (show CHKB Proteins) and TPI1 (show TPI1 Proteins) were weakly associated with schizophrenia;in addition, IFNG (show IFNG Proteins) polymorphisms were associated with schizophrenia; results suggest that IFNG (show IFNG Proteins) and proteins affected by IFNG (show IFNG Proteins) may play a role in the pathogenesis of schizophrenia

  6. de-methylated CKB (show CHKB Proteins) gene is inherited that leads to high CKB (show CHKB Proteins) expression levels in myeloic precursor cells in the bone marrow

  7. His103 and Phe107 in hASB9-2 are essential for binding to CKB (show CHKB Proteins).

  8. Cigarette smoke induced carbonylation and subsequent degradation of creatine kinase B are involved in the regulation of senescence in bronchial epithelial cells.

  9. Data demonstrate that the downregulation of CKB (show CHKB Proteins) may play an important role in colon cancer progression by promoting EMT (show ITK Proteins).

  10. CKB (show CHKB Proteins) was up-regulated in women older than 38 years, and its expression in cumulus cells was associated with embryo quality

Mouse (Murine) Creatine Kinase, Brain (CKB) interaction partners

  1. Loss of normal CKB (show CHKB Proteins) structure and function contributes to the mechanisms by which isoaspartate accumulation leads to central nervous system dysfunction in the PIMT (show PCMT1 Proteins)-Knockout mouse.

  2. CKB (show CHKB Proteins) plays a key role in myotube formation by limiting myoblast fusion during myogenesis.

  3. BCK phosphorylation at Ser6 did not affect its enzymatic activity, but led to the appearance of the phosphorylated enzyme at the endoplasmic reticulum (ER)

  4. Hypothalamic plasticity of neuropeptide Y (show NPY Proteins) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation

  5. negative regulation of CKB (show CHKB Proteins) by mHTT is a key event in the pathogenesis of HD and contributes to the neuronal dysfunction associated with HD.

  6. reduced expression of brain creatine kinase in the cochlea of Huntington disease (show HTT Proteins) mice is associated with hearing impairment

  7. In rat cerebrum and cerebellum, as in rat heart, at all ages the several cCK (show CCK Proteins) isoenzymes do participate in a gender-specific manner, in favor of females, in diverse functions of the different cell compartments of glial and neuronal cells.

  8. cytoskeletal dynamics during cell motility is coupled to on-site availability of ATP generated by CKB (show CHKB Proteins)

Creatine Kinase, Brain (CKB) Protein Profile

Protein Summary

The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.

Gene names and symbols associated with Creatine Kinase, Brain Proteins (CKB)

  • creatine kinase, brain b (ckbb)
  • creatine kinase, brain (ckb)
  • creatine kinase, brain (CKB)
  • choline kinase beta (Chkb)
  • Creatine kinase B-type-like (LOC100337842)
  • creatine kinase, brain (Ckb)
  • B-CK protein
  • Bck protein
  • cb594 protein
  • Chetk protein
  • Chkl protein
  • Ck-3 protein
  • Ck3 protein
  • CKB protein
  • Ckbb protein
  • Ckbr protein
  • wu:fj36f10 protein
  • wu:fj37d11 protein

Protein level used designations for Creatine Kinase, Brain Proteins (CKB)

brain creatine kinase b , brain creatine kinase , creatine kinase B-type , creatine kinase, brain , creatine kinase B , CK , CKB , CKEKB , EK , choline/ethanolamine kinase , choline/ethanolamine kinase beta , ethanolamine kinase , creatine kinase B chain , creatine kinase-B , B-CK , B-creatine kinase , alternate protein , Creatine kinase B chain , Creatine kinase B-type

140744 Danio rerio
380055 Xenopus laevis
453185 Pan troglodytes
711167 Macaca mulatta
733543 Xenopus (Silurana) tropicalis
100190977 Ovis aries
29367 Rattus norvegicus
100337842 Oryctolagus cuniculus
1152 Homo sapiens
12709 Mus musculus
24264 Rattus norvegicus
516210 Bos taurus
396248 Gallus gallus
480443 Canis lupus familiaris
100627332 Sus scrofa
100009085 Oryctolagus cuniculus
100735800 Cavia porcellus
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