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CKB Protein (His tag)

CKB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319644
  • Target See all CKB Proteins
    CKB (Creatine Kinase, Brain (CKB))
    Protein Type
    Recombinant
    Origin
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 12
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CKB protein is labelled with His tag.
    Purpose
    Recombinant Human Creatine Kinase BB/CKB Protein (His Tag)
    Sequence
    Met1-Lys381
    Characteristics
    Recombinant Human Creatine Kinase BB is produced by our E.coli expression system and the target gene encoding Met1-Lys381 is expressed with a 6His tag at the N-terminus.
    Purity
    > 90 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CKB Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    CKB (Creatine Kinase, Brain (CKB))
    Alternative Name
    Creatine Kinase BB/CKB (CKB Products)
    Synonyms
    B-CK Protein, CKBB Protein, b-ck Protein, ckbb Protein, CKB Protein, Bck Protein, Ck-3 Protein, Ck3 Protein, Ckbb Protein, bck Protein, ckb Protein, cb594 Protein, wu:fj36f10 Protein, wu:fj37d11 Protein, Ckbr Protein, mg:cb02h12 Protein, wu:fb62d04 Protein, wu:fc14g11 Protein, zgc:154095 Protein, zgc:92079 Protein, creatine kinase B Protein, creatine kinase, brain L homeolog Protein, creatine kinase B-type Protein, creatine kinase, brain Protein, creatine kinase, brain b Protein, creatine kinase, brain a Protein, CKB Protein, ckb.L Protein, Ckb Protein, ckb Protein, ckbb Protein, ckba Protein
    Background

    Background: Creatine kinase B-type (CKB) belongs to the ATP:guanido phosphotransferase family. It has dimer of identical or non-identical chains with MM being the major form in skeletal muscle and myocardium. MB exists in myocardium, and BB exists in many tissues, especially brain. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Clinically, creatine kinase is assayed in blood tests as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, autoimmune myositides and acute renal failure.

    Synonym: B-CK, CKB, Creatine Kinase BB

    Molecular Weight
    44.8 kDa
    UniProt
    P12277
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