CKB Protein (His tag)
Quick Overview for CKB Protein (His tag) (ABIN7319644)
Target
See all CKB ProteinsProtein Type
Origin
Source
Purity
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Purification tag / Conjugate
- This CKB protein is labelled with His tag.
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Purpose
- Recombinant Human Creatine Kinase BB/CKB Protein (His Tag)
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Sequence
- Met1-Lys381
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Characteristics
- Recombinant Human Creatine Kinase BB is produced by our E.coli expression system and the target gene encoding Met1-Lys381 is expressed with a 6His tag at the N-terminus.
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Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
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Restrictions
- For Research Use only
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Format
- Frozen, Liquid
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Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl,10 % Glycerol, pH 7.5.
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- CKB (Creatine Kinase, Brain (CKB))
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Alternative Name
- Creatine Kinase BB/CKB
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Background
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Background: Creatine kinase B-type (CKB) belongs to the ATP:guanido phosphotransferase family. It has dimer of identical or non-identical chains with MM being the major form in skeletal muscle and myocardium. MB exists in myocardium, and BB exists in many tissues, especially brain. CKB reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Clinically, creatine kinase is assayed in blood tests as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, autoimmune myositides and acute renal failure.
Synonym: B-CK, CKB, Creatine Kinase BB
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Molecular Weight
- 44.8 kDa
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UniProt
- P12277
Target
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