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Cystatin D Proteins (CST5)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping Cystatin D Antibodies (28) and Cystatin D Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CST5 1473 P28325
Mouse CST5 CST5 58214  
Rat CST5 CST5 366219  
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Top Cystatin D Proteins at

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human Cystatin D, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 2 to 3 Days
HOST_Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
HOST_Human Human His tag   10 μg Log in to see 11 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
HOST_HEK-293 Cells Human His tag Validation with Western Blot 10 μg Log in to see 12 to 15 Days

CST5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, ,

Top referenced Cystatin D Proteins

  1. Human CST5 Protein expressed in Human Cells - ABIN2002971 : Freije, Abrahamson, Olafsson, Velasco, Grubb, López-Otín: Structure and expression of the gene encoding cystatin D, a novel human cysteine proteinase inhibitor. in The Journal of biological chemistry 1991 (PubMed)
    Show all 3 references for ABIN2002971

  2. Human CST5 Protein expressed in HEK-293 Cells - ABIN2180922 : Balbín, Hall, Grubb, Mason, López-Otín, Abrahamson: Structural and functional characterization of two allelic variants of human cystatin D sharing a characteristic inhibition spectrum against mammalian cysteine proteinases. in The Journal of biological chemistry 1994 (PubMed)
    Show all 2 references for ABIN2180922

More Proteins for Cystatin D (CST5) Interaction Partners

Human Cystatin D (CST5) interaction partners

  1. Results imply CST5 as an important mediator of tumor suppression by p53 (show TP53 Proteins) in colorectal cancer.

  2. These results support an unanticipated role of cystatin D in the cell nucleus, controlling the transcription of specific genes involved in crucial cellular functions, which may mediate its protective action in colon cancer.

  3. activation of the RhoA (show RHOA Proteins)-ROCK-p38MAPK (show MAPK14 Proteins)-MSK signaling pathway is essential for the regulation of the phenotype and of the CST5/cystatin D candidate tumor suppressor and other target genes by 1,25(OH)2D3 in colon cancer cells

  4. Compared with its homologues, cystatin D presents an unusual inhibition profile with a preferential inhibition cathepsin S (show CTSS Proteins) > cathepsin H (show CTSH Proteins) > cathepsin L (show CTSL1 Proteins) and no inhibition of cathepsin B (show CTSB Proteins) or pig legumain (show LGMN Proteins).

  5. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.

Mouse (Murine) Cystatin D (CST5) interaction partners

  1. Cst10 may play an important role in the last steps of the chondrocyte differentiation pathway as an inducer of maturation, followed by apoptosis of chondrocytes

  2. Data show that cystatin (show CST3 Proteins) 10 (carminerin) contributes to chondrocyte calcification during endochondral ossification under physiological and pathological conditions through the transcriptional inhibition of NPP1 (show ENPP1 Proteins).

Cystatin D (CST5) Protein Profile

Protein Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.

Gene names and symbols associated with Cystatin D Proteins (CST5)

  • cystatin D (CST5)
  • cystatin 10 (chondrocytes) (Cst10)
  • cystatin D (Cst5)
  • Cst10 protein
  • Cystatin-5 protein
  • DD72 protein

Protein level used designations for Cystatin D Proteins (CST5)

cystatin-D , cystatin 5 , cystatin-5 , cysteine-proteinase inhibitor , cystatin 10 (chondrocytes)

1473 Homo sapiens
58214 Mus musculus
704408 Macaca mulatta
366219 Rattus norvegicus
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