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Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 Proteins (CYP3A5)

CYP3A5,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP3A5 Antibodies (39) and CYP3A5 Kits (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP3A5 1577 P20815
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Top CYP3A5 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CYP3A5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5) Interaction Partners

Human Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5) interaction partners

  1. findings suggest that the presence of the CYP3A5*1 allele contributes to marked elevation of CYP3A activity associated with recovery of renal function after kidney transplantation

  2. CYP3A5 genetic polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations.

  3. Early postpartum women possessed higher CYP3A activity based on plasma 4beta-hydroxycholesterol and had a large pharmacokinetic variability in amlodipine disposition.

  4. The polymorphism of ABCB1 (show ABCB1 Proteins) (C3435T) has an important role in the manifestation of toxicities and drug exposure, but not polymorphism of CYP3A5.

  5. a critical role of the CYP3A5 6986A>G and CYP3A4 (show CYP3A4 Proteins) -392A>G polymorphisms on the variation of Tac (show IL2RA Proteins) exposure during the early and the late post-transplant phase, respectively.

  6. rs776746 and rs15524 in the CYP3A5 gene tend to affect carbamazepine metabolism in patients with epilepsy.

  7. CYP3A5 genotyping and dose adjustments of tacrolimus should be performed to prevent acute renal dysfunction in lupus nephritis patients taking tacrolimus once daily

  8. CYP3A5*1 in either the donor or recipient resulted in higher mean daily doses of tacrolimus or its modified formulation to achieve target drug exposure in liver transplant patients.

  9. Case Report: increased tacrolimus trough concentrations due to inhibition of CYP3A4 (show CYP3A4 Proteins) following nicardipine administration.

  10. Genotyping of CYP3A4 (show CYP3A4 Proteins)/MDR1/NR1I2 (show NR1I2 Proteins) polymorphisms may be helpful for better guiding tacrolimus dosing in CYP3A5 nonexpressers.

CYP3A5 Protein Profile

Protein Summary

This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.

Gene names and symbols associated with CYP3A5

  • cytochrome P450, family 3, subfamily A, polypeptide 5 (CYP3A5)
  • CP35 protein
  • CYPIIIA5 protein
  • P450PCN3 protein
  • PCN3 protein

Protein level used designations for CYP3A5

cytochrome P450 3A5 , aryl hydrocarbon hydroxylase , cytochrome P450 HLp2 , cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5 , cytochrome P450-PCN3 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase

737374 Pan troglodytes
1577 Homo sapiens
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