DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) ELISA Kits

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3A Antibodies (274) and DNMT3A Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT3A 1788 Q9Y6K1
Anti-Rat DNMT3A DNMT3A 444984 Q1LZ53
Anti-Mouse DNMT3A DNMT3A 13435 O88508
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Top DNMT3A ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details

More ELISA Kits for DNMT3A Interaction Partners

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1 (show DNMT1 ELISA Kits), Dnmt3a, Hdac1 (show HDAC1 ELISA Kits), Kdm3a (show KDM3A ELISA Kits) and Uhrf1 (show UHRF1 ELISA Kits) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

Human DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Dnmt3a2 is at the core of memory processes and represents a novel target for cognition-enhancing therapies to ameliorate anxiety and fear disorders and boost memory consolidation.

  2. Data indicate that DNMT3A allele G of rs1550117 was associated with an increased risk of non-small cell lung cancer (NSCLC) susceptibility and binding affinity of transcription repressor SP1 (show PSG1 ELISA Kits).

  3. The results show that DNMT3A mutations are associated with an unfavourable clinical outcome in our Southeast Asian AML (show RUNX1 ELISA Kits) patient cohort.

  4. DNMT3A mutations were rare in Chinese children with acute myeloid leukemia (show BCL11A ELISA Kits) (AML (show RUNX1 ELISA Kits)). The mutation positions were different from the hotspots reported in adult AML (show RUNX1 ELISA Kits). DNMT3A mutations may have adverse impact on prognosis of children with AML (show RUNX1 ELISA Kits).

  5. Somatic mutations driving clonal hematopoiesis occur mainly in DNMT3A and TET2 (show TET2 ELISA Kits) and have no significant impact on hematological phenotypes. There is a familial predisposition to acquire TET2 (show TET2 ELISA Kits) mutation.

  6. Findings identify a crucial role for DNMT3A(R882) mutations in driving acute myeloid leukemia anthracylcine chemoresist (show FLT3 ELISA Kits)ance and hi (show FLT3 ELISA Kits)ghlight the importance of ch (show NPM1 ELISA Kits)romatin rem (show NPM1 ELISA Kits)odeling in respons (show RUNX1 ELISA Kits)e to cytotoxic chemotherapy.

  7. Studies indicate that DNA methylation (show HELLS ELISA Kits) is mediated by three DNA (Cytosine-5-)-Methyltransferase (DNMTs): DNMT1 (show DNMT1 ELISA Kits) is responsible for the maintenance of methylation patterns after DNA replication whereas DNMT3A and DNMT3B (show DNMT3B ELISA Kits) carry out de novo methylation, and DNMT (show DNMT1 ELISA Kits) inhibitors have showed promising results in clinical trials of prostate cancer.

  8. dysregulation of DNMT3A and IGFBP5 (show IGFBP5 ELISA Kits) is relevant to preeclampsia. Thus, we propose that DNMT3A and IGFBP5 (show IGFBP5 ELISA Kits) can serve as potential markers and targets for the clinical diagnosis and therapy of preeclampsia.

  9. DOT1L (show DOT1L ELISA Kits) may play a critical role in DNMT3A-mutant leukemia.

  10. LOXL1 (show LOXL1 ELISA Kits) transcriptional activity was dramatically reduced when a recombinant DNMT3A was concomitantly overexpressed.

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (show HELLS ELISA Kits) content are rather a function of time, and not a genetic component.

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. The effect of p53 (show TP53 ELISA Kits) expression on the development of cloned embryos, and its interaction with HDAC1 (show HDAC1 ELISA Kits) and DNMT3A are reported.

  2. The expression levels of DNMT3a and DNMT3b (show DNMT3B ELISA Kits) were associated with several beef quality traits.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Loss of DNMT3A expression is associated with development of malignancy.

  2. confirm the transformation potential of DNMT3A(R882H) Tet2 (show TET2 ELISA Kits)(-/-) progenitors and represent the first cooperative model in mice involving Tet2 (show TET2 ELISA Kits) inactivation driving lymphoid malignancies

  3. overexpression of Dnmt3a partially rescued the impairment of adipogenesis induced by AP2alpha (show TFAP2A ELISA Kits) knockdown.

  4. These data show that DNMT3a plays an important role in regulating embryonic cardiomyocyte gene expression, morphology and function.

  5. in addition to the established role of Dnmt3a in regulating self-renewal, Dnmt3a regulates tissue tropism and limits myeloid progenitor expansion in vivo.

  6. Dnmt3a mutations induced hematopoietic stem cell expansion, cooperated with mutations in the FMS-like tyrosine kinase 3 (show FLT3 ELISA Kits) gene (Flt3 (show FLT3 ELISA Kits)(ITD)) and the nucleophosmin (show NPM1 ELISA Kits) gene (Npm1 (show GJA1 ELISA Kits)(c)) to induce AML (show RUNX1 ELISA Kits) in vivo, and promoted resistance to anthracycline chemotherapy.

  7. miR (show MLXIP ELISA Kits)-29a/b/c repressed DNMT3A expression by directly targeting its 3' untranslated region (3' UTR (show UTS2R ELISA Kits)). Our data reveal a novel mechanism of miR (show MLXIP ELISA Kits)-29a/b/c in the regulation of adipogenesis

  8. DOT1L (show DOT1L ELISA Kits) may play a critical role in DNMT3A-mutant leukemia.

  9. Thyroid regulation of Dnmt3a may be an evolutionarily conserved mechanism for modulating global changes in DNA methylation (show HELLS ELISA Kits) during postnatal neurological development.

  10. three DNA methyltransferases, Dnmt1 (show DNMT1 ELISA Kits), Dnmt3a, and Dnmt3b (show DNMT3B ELISA Kits), have been identified. Dnmt3a and Dnmt3b (show DNMT3B ELISA Kits) are responsible for establishing DNA methylation (show HELLS ELISA Kits) patterns produced through their de novo-type DNA methylation (show HELLS ELISA Kits) activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l (show TRDMT1 ELISA Kits)), which is a member of the Dnmt3 family but does not possess DNA methylation (show HELLS ELISA Kits)

DNMT3A Antigen Profile

Antigen Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with DNMT3A

  • DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A) antibody
  • DNA methyltransferase 3A (dnmt3a) antibody
  • DNA (cytosine-5-)-methyltransferase 3 alpha (Dnmt3a) antibody
  • DNA methyltransferase 3A (Dnmt3a) antibody
  • DNMT3A antibody
  • DNMT3A2 antibody
  • M.HsaIIIA antibody
  • MmuIIIA antibody

Protein level used designations for DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha , DNA cytosine methyltransferase 3 alpha , DNA (cytosine-5)-methyltransferase 3A , DNA methyl transferase alpha , DNA methyltransferase 3A , DNA MTase HsaIIIA , DNA cytosine methyltransferase 3A2 , DNA-methyltransferase 3a , DNA MTase MmuIIIA , DNA methyltransferase MmuIIIA

GENE ID SPECIES
482996 Canis lupus familiaris
694822 Macaca mulatta
739139 Pan troglodytes
100037301 Sus scrofa
100030681 Monodelphis domestica
100344715 Oryctolagus cuniculus
100500776 Ovis aries
100594618 Nomascus leucogenys
100529107 Anolis carolinensis
1788 Homo sapiens
421991 Gallus gallus
100510798 Felis catus
100055881 Equus caballus
359716 Bos taurus
444984 Rattus norvegicus
13435 Mus musculus
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