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DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) ELISA Kits

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3A Antibodies (272) and DNMT3A Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DNMT3A 1788 Q9Y6K1
Anti-Rat DNMT3A DNMT3A 444984 Q1LZ53
Anti-Mouse DNMT3A DNMT3A 13435 O88508
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Top DNMT3A ELISA Kits at antibodies-online.com

Showing 1 out of 3 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.061 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for DNMT3A Interaction Partners

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1 (show DNMT1 ELISA Kits), Dnmt3a, Hdac1 (show HDAC1 ELISA Kits), Kdm3a (show KDM3A ELISA Kits) and Uhrf1 (show UHRF1 ELISA Kits) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

Human DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. DNMT3A haploinsufficiency results in reversible epigenetic alterations that transform FLT3 (show FLT3 ELISA Kits)(ITD)-mutant myeloproliferative neoplasm into AML (show RUNX1 ELISA Kits).

  2. DNMT1 (show DNMT1 ELISA Kits), DNMT3A and DNMT3B (show DNMT3B ELISA Kits) are highly expressed in human medulloblastoma samples

  3. show that DNMT3A loss synergizes with the FLT3 (show FLT3 ELISA Kits) internal tandem duplication in a dose-influenced fashion to generate rapid lethal lymphoid or myeloid leukemia (show BCL11A ELISA Kits). Loss of DNMT3A leads to reduced DNA methylation (show HELLS ELISA Kits), predominantly at hematopoietic enhancer regions supporting its role as a guardian of the epigenetic state at enhancer regions, critical for inhibition of leukemic transformation.

  4. The present study suggests that MTHFR (show MTHFR ELISA Kits) methylation is increased in thymomas obtained from Myasthenia Gravis patients; furthermore, some degrees of methylation of the DNMT3A gene were observed in thymic tissue with respect to blood.

  5. Study provides evidence that Arg882-mutated DNMT3A contributes to acute myeloid leukemia (show BCL11A ELISA Kits) pathogenesis through epigenetic activation of leukemia-related genes.

  6. Downregulation of DNMT3a regulated miR (show MLXIP ELISA Kits)-182 via caspase-3 (show CASP3 ELISA Kits) and -9-mediated apoptosis and DNA damage response in ovarian cancer.

  7. Approximately 22% of AML (show RUNX1 ELISA Kits) and 36% of cytogenetically normal AML (show RUNX1 ELISA Kits) cases carry DNMT3A mutations and around 60% of these mutations affect the R882 codon. These mutations have been associated with poor prognosis and adverse survival outcomes for AML (show RUNX1 ELISA Kits) patients.

  8. The DNMT3A -448A > G polymorphism may be a novel functional SNP and contribute to its genetic susceptibility to spontaneous abortion in Chinese women, and ART may not affect the distribution of -448A > G in pregnancy loss and normal pregnancy. The observed TT genotype of DMNT3B suggests that this is the predominant genotype of this population

  9. Significant upregulation of DNMT1 (show DNMT1 ELISA Kits), DNMT3A, and DNMT3B (show DNMT3B ELISA Kits) expression was found in para-carcinoma tissues, compared with the histopathologically unchanged tissues furthermore, distinguishable expression profiling was observed of target miRNAs in tissues with different distance

  10. A potential role of rs2424913 (DNMT3B (show DNMT3B ELISA Kits)) and rs2228611 (DNMT1 (show DNMT1 ELISA Kits)) in autoimmune thyroid diseases (AITD) susceptibility and identified novel gene-gene/gene-sex interactions in AITD. This may highlight sex and genes of DNMTs family as contributors to the pathogenesis of AITD.

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (show HELLS ELISA Kits) content are rather a function of time, and not a genetic component.

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. The effect of p53 (show TP53 ELISA Kits) expression on the development of cloned embryos, and its interaction with HDAC1 (show HDAC1 ELISA Kits) and DNMT3A are reported.

  2. The expression levels of DNMT3a and DNMT3b (show DNMT3B ELISA Kits) were associated with several beef quality traits.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) interaction partners

  1. DNMT3A haploinsufficiency results in reversible epigenetic alterations that transform FLT3 (show FLT3 ELISA Kits)(ITD)-mutant myeloproliferative neoplasm into AML (show RUNX1 ELISA Kits).

  2. Dnmt3a-cKO muscles exhibit fewer Pax7 (show PAX7 ELISA Kits)+ SCs (show TWIST1 ELISA Kits), which show increased expression of p57Kip2 (show CDKN1C ELISA Kits) protein

  3. Study provides evidence that Arg882-mutated DNMT3A contributes to acute myeloid leukemia (show BCL11A ELISA Kits) pathogenesis through epigenetic activation of leukemia-related genes.

  4. Dnmt3a is a haplo-insufficient (show TGFb ELISA Kits) tumor suppressor in chronic lymphocytic leukemia and highlights the importance of deregulated molecular events in disease pathogenesis.

  5. Cigarette smoke induces proteosomal-mediated degradation of DNMT3a in embryonic orofacial cells.

  6. The stress-induced Brg1 (show SMARCA4 ELISA Kits)-G9a (show EHMT2 ELISA Kits)/GLP (show GOLGA6A ELISA Kits)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 ELISA Kits) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  7. both the PML (show PML ELISA Kits)-RARA (show RARA ELISA Kits)-driven competitive transplantation advantage and development of acute promyelocytic leukemia (show PML ELISA Kits) (APL (show FASL ELISA Kits)) required DNMT3A

  8. Overexpression or knockdown of medial prefrontal cortex Dnmt3a levels decreases or increases anxiety-like behavior, respectively.

  9. DKO cardiomyocytes showed virtual absence of targeted Dnmt3a and Dnmt3b (show DNMT3B ELISA Kits) mRNA transcripts.

  10. An unexpected oncogenic role for Dnmt3a in MTCL through methylation-independent repression of Dnmt3b (show DNMT3B ELISA Kits).

DNMT3A Antigen Profile

Antigen Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with DNMT3A

  • DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A) antibody
  • DNA methyltransferase 3A (dnmt3a) antibody
  • DNA (cytosine-5-)-methyltransferase 3 alpha (Dnmt3a) antibody
  • DNA methyltransferase 3A (Dnmt3a) antibody
  • DNMT3A antibody
  • DNMT3A2 antibody
  • M.HsaIIIA antibody
  • MmuIIIA antibody

Protein level used designations for DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha , DNA cytosine methyltransferase 3 alpha , DNA (cytosine-5)-methyltransferase 3A , DNA methyl transferase alpha , DNA methyltransferase 3A , DNA MTase HsaIIIA , DNA cytosine methyltransferase 3A2 , DNA-methyltransferase 3a , DNA MTase MmuIIIA , DNA methyltransferase MmuIIIA

GENE ID SPECIES
482996 Canis lupus familiaris
694822 Macaca mulatta
739139 Pan troglodytes
100037301 Sus scrofa
100030681 Monodelphis domestica
100344715 Oryctolagus cuniculus
100500776 Ovis aries
100594618 Nomascus leucogenys
100529107 Anolis carolinensis
1788 Homo sapiens
421991 Gallus gallus
100510798 Felis catus
100055881 Equus caballus
359716 Bos taurus
444984 Rattus norvegicus
13435 Mus musculus
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