You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Deleted in Colorectal Carcinoma (DCC) Antibodies

DCC encodes a netrin 1 receptor. Additionally we are shipping DCC Proteins (8) and DCC Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCC 27421 Q9R1S7
DCC 1630 P43146
DCC 25311 Q63155
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DCC Antibodies at antibodies-online.com

Showing 10 out of 86 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), WB DCC Antibody (Center) (ABIN656268) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using DCC Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human stomach tissue stained with Netrin receptor DCC  Antibody  followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of Netrin receptor DCC  Antibody  in Mouse heart tissue lysates (35ug/lane). This demonstrates the DCC antibody detected the DCC protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, WB Western blot analysis of human DCC protein in 293 human embryonic kidney cells stably transfected with an expression vector containing full length DCC cDNA. Lane 1, clone G97-449 (ABIN967443), which recognizes an epitope in the intracellular domain of DCC. Lane 2, clone G92-13 (ABIN967442), which recognizes an epitope in the extracellular domain of DCC. Lane 3, a mouse IgG1 isotype control. 0.1 mg Log in to see 5 to 6 Days
$285.19
Details
Human Mouse Un-conjugated IHC (f), WB Western blot analysis of human DCC protein in 293 human embryonic kidney cells stably transfected with an expression vector containing full length DCC cDNA. Lane 1, clone G97-449 (ABIN967443), which recognizes an epitope in the intracellular domain of DCC. Lane 2, clone G92-13 (ABIN967442), which recognizes an epitope in the extracellular domain of DCC. Lane 3, a mouse IgG1 isotype control. 0.1 mg Log in to see 5 to 6 Days
$236.41
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-DCC Antibody Titration: 0.2-1 ug/mlPositive Control: ACHN cell lysate WB Suggested Anti-DCC  Antibody Titration: 0.2-1 µg/mL  Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-DCC antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate Lane 3: U87 Cell Lysate Lane 4: SW620 Cell Lysate Lane 5: COLO320 Cell Lysate Lane 6: 293T Cell Lysate Lane 7: HELA Cell Lysate Anti-DCC antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated IHC (p) Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of DCC expression in ACHN (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

DCC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,
,

, , , , ,
Human , , , ,
, ,
,

Rat (Rattus) , ,
,


Top referenced anti-DCC Antibodies

  1. Human Monoclonal DCC Primary Antibody for FACS, WB - ABIN967442 : Fearon, Cho, Nigro, Kern, Simons, Ruppert, Hamilton, Preisinger, Thomas, Kinzler: Identification of a chromosome 18q gene that is altered in colorectal cancers. in Science (New York, N.Y.) 1990 (PubMed)
    Show all 5 references for ABIN967442

  2. Human Monoclonal DCC Primary Antibody for IHC (f), WB - ABIN967443 : Fearon, Hamilton, Vogelstein: Clonal analysis of human colorectal tumors. in Science (New York, N.Y.) 1987 (PubMed)
    Show all 5 references for ABIN967443

  3. Mouse (Murine) Polyclonal DCC Primary Antibody for IHC (p), WB - ABIN656268 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 3 references for ABIN656268

  4. Human Polyclonal DCC Primary Antibody for EIA, IHC (p) - ABIN953653 : Hanna, Kruskal, Ezekowitz, Bloom, Collier: Role of macrophage oxidative burst in the action of anthrax lethal toxin. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Show all 2 references for ABIN953653

  5. Human Polyclonal DCC Primary Antibody for IF, ELISA - ABIN1534435 : Cho, Oliner, Simons, Hedrick, Fearon, Preisinger, Hedge, Silverman, Vogelstein: The DCC gene: structural analysis and mutations in colorectal carcinomas. in Genomics 1994 (PubMed)
    Show all 2 references for ABIN1534435

More Antibodies against DCC Interaction Partners

Mouse (Murine) Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. dcc haploinsufficient mice acquire intracranial self-stimulation behavior and that the parameters of the stimulation are comparable to those observed in wild-type littermates; reduced expression of dcc may dampen the abuse potential of cocaine

  2. Identified the Dcc gene as a novel downstream target of spontaneous calcium activity involved in axon growth.

  3. bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 (show ABCC6 Antibodies) gene.

  4. suggest that DCC signaling functions through NCK1 (show NCK1 Antibodies) and NCK2 (show NCK2 Antibodies) and that both proteins are necessary for the establishment of normal spinal circuits necessary for gait

  5. Results suggest that down syndrome cell adhesion molecule (show DSCAM Antibodies) collaborates with deleted in colorectal cancer to regulate microtubule dynamics via direct binding to dynamic TUBB3 (show TUBB3 Antibodies) in Netrin-1 (show NTN1 Antibodies)-induced axon branching.

  6. In a mouse model of CKD, ABCC6 (show ABCC6 Antibodies) protein expression was decreased in liver and kidney, however mRNA levels were unchanged.

  7. Data indicate the roles of Slit1 (show SLIT1 Antibodies)/Robo1 (show ROBO1 Antibodies) and Netrin1/DCC signals in positioning motor neuron cell bodies.

  8. These data demonstrate robust cardioprotective effect of netrin-1 (show NTN1 Antibodies) in vivo, as shown by reduced infarct size and improved cardiac function mediated by netrin-1 (show NTN1 Antibodies) receptor DCC.

  9. Unc5C (show Unc5c Antibodies) and DCC act downstream of Ctip2 (show BCL11B Antibodies) and Satb2 (show SATB2 Antibodies) and contribute to corpus callosum formation.

  10. DCC appears to have a somewhat limited role in methamphetamine consumption and seeking following abstinence

Zebrafish Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Schwann cell and dcc-mediated guidance are critical early during regeneration to direct growth cones across the transection gap and onto their original axonal trajectory.

  2. in dcc mutants, turns on the inappropriate side of the body are caused by aberrant ipsilateral axonal projections

  3. Dcc-Netrin1 and roundabout2 (Robo2)-Slit coordinate axonal projection choices of neurons in the developing forebrain.

  4. Dcc regulates polarized axon initiation and asymmetric outgrowth of forebrain neurons

  5. dcc may play roles not only in axon guidance, but in morphogenesis and functioning of these organs as well

  6. First evidence that Netrin/DCC axon guidance molecules act in dendrites in a vertebrate system.

Human Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. The study identified DCC as a differentially expressed gene and clustered meningiomas into DCC low expression (3 grade I and 3 grade II tumors), DCC medium expression (2 grade I and 1 grade II tumors), and DCC high expression (5 grade I tumors) groups.

  2. Data suggest that, in response to netrin-1 (show NTN1 Antibodies)/netrin receptor (DCC) signaling, p120RasGAP (show RASA1 Antibodies) is recruited to growth cones and supports axon outgrowth; p120RasGAP (show RASA1 Antibodies) Src (show SRC Antibodies) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  3. By analyzing multiple myeloma-derived cell lines and patient-derived primary CD138 (show SDC1 Antibodies)-positive plasma cells ... authors show for the first time that transcriptional dysregulation of DCC is involved in the progression of plasma cell malignancy.

  4. the transfected DCC gene can suppress cell proliferation and lead to downregulation of CEA (show CEACAM5 Antibodies) expression in SW1116 cells.

  5. Signaling mechanism of the netrin-1 (show NTN1 Antibodies) receptor DCC in axon guidance

  6. NTN1 (show NTN1 Antibodies)-DCC pathway contains targets of FDA-approved drugs and may offer promise for guiding applied clinical research on preventive and therapeutic interventions for AMD (show AMD1 Antibodies)

  7. DCC mutation correlated with fractionated mirroring in individuals with Congenital mirror movements

  8. Data show that silencing ezrin-radixin-moesin (ERM (show MSN Antibodies)) protein expression ablates deleted in colorectal carcinoma protein (DCC)-protein kinase A (PKA) interaction and specifically blocks netrin-induced PKA activity and phosphorylation.

  9. Migration of CD166 (show ALCAM Antibodies) positive progenitor cells to sites of cartilage damage may be directed by regulation of DCC/CREB (show CREB1 Antibodies) signaling.

  10. Three novel truncating mutations of DCC are associated with congenital mirror movements.

DCC Antigen Profile

Protein Summary

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Gene names and symbols associated with DCC

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6) antibody
  • deleted in colorectal carcinoma (DCC) antibody
  • deleted in colorectal carcinoma (dcc) antibody
  • deleted in colorectal carcinoma (Dcc) antibody
  • Abcc1b antibody
  • C030036D22Rik antibody
  • CRC18 antibody
  • CRCR1 antibody
  • DCC antibody
  • dcca-A antibody
  • dyscalc antibody
  • Dyscalc1 antibody
  • Igdcc1 antibody
  • MRMV1 antibody
  • Mrp6 antibody
  • xdcc antibody
  • XDCCa antibody
  • zdcc antibody

Protein level used designations for DCC

ATP-binding cassette sub-family C member 6 , ATP-binding cassette, sub-family C, member 6 , multidrug resistance-associated protein 6 , multidrug resistance-associated protein-6 , deleted in colorectal carcinoma , netrin receptor DCC , deleted in colorectal cancer , deleted in colorectal cancer tumor suppressor , netrin receptor DCC-like , colorectal cancer suppressor , colorectal tumor suppressor , deleted in colorectal cancer protein , immunoglobulin superfamily DCC subclass member 1 , immunoglobulin superfamily, DCC subclass, member 1 , tumor suppressor protein DCC

GENE ID SPECIES
27421 Mus musculus
455425 Pan troglodytes
483976 Canis lupus familiaris
537176 Bos taurus
569360 Danio rerio
693352 Macaca mulatta
100054013 Equus caballus
378529 Xenopus laevis
100442362 Pongo abelii
100410745 Callithrix jacchus
100556072 Anolis carolinensis
100583619 Nomascus leucogenys
1630 Homo sapiens
13176 Mus musculus
25311 Rattus norvegicus
Selected quality suppliers for anti-DCC (DCC) Antibodies
Did you look for something else?