DCC antibody (C-Term)

Catalog No. ABIN1536718

This Rabbit Polyclonal antibody specifically detects DCC in WB. It exhibits reactivity toward Mouse.

Quick Overview for DCC antibody (C-Term) (ABIN1536718)

Target: DCC (Deleted in Colorectal Carcinoma (DCC))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCC antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40015

Product Details anti-DCC Antibody

Binding Specificity: AA 1391-1417, C-Term

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Dcc antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1391-1417 amino acids from the C-terminal region of mouse Dcc.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Mouse Dcc Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for DCC

Target: DCC (Deleted in Colorectal Carcinoma (DCC))

Alternative Name: Dcc

Background: Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

Molecular Weight: 158341

Gene ID: 13176

NCBI Accession: NP_031857

UniProt: P70211

Pathways: Regulation of Cell Size