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Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) ELISA Kits

The protein encoded by DOK1 is part of a signal transduction pathway downstream of receptor tyrosine kinases. Additionally we are shipping DOK1 Antibodies (220) and DOK1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DOK1 109978 Q9CRA0
DOK1 312477 Q4QQV2
DOK1 1796 Q99704
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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
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96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days
96 Tests Log in to see 11 to 13 Days

More ELISA Kits for DOK1 Interaction Partners

Mouse (Murine) Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) interaction partners

  1. Dok1 knockdown attenuated TLR2 (show TLR2 ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation and IL-6 (show IL6 ELISA Kits) production in microglia.

  2. Triple Dok1 Doc2 (show DOC2A ELISA Kits) Doc3 knockout leads to spontaneous pulmonary inflammation with hallmarks of asthma.

  3. Dok-1 overexpression promotes the generation of an innate-like CD8 (show CD8A ELISA Kits)(+) T-cell population that expresses Eomesodermin (show EOMES ELISA Kits).

  4. Studies using SHIP-1 (show INPP5D ELISA Kits) shRNA, knockout mice and decoy inhibitors further indicate that CD4 (show CD4 ELISA Kits)-mediated inhibition of TCR-mediated T cell activation is SHIP-1 (show INPP5D ELISA Kits) and Dok-1/2 dependent, and involves SHIP-1 (show INPP5D ELISA Kits) hydrolysis of Phosphatidylinositol 3,4,5-trisphosophate

  5. Dok-1 and Dok-2 deficiency induces osteopenia by activation of osteoclasts.

  6. these findings indicate that Dok-1, Dok-2, and Dok-3 (show DOK3 ELISA Kits) cooperatively suppress aggressive HS

  7. Role of Dok1 in RET (show RET ELISA Kits)-mediated signaling

  8. crystal structure of the Dok1 phosphotyrosine binding domain alone and in complex with a phosphopeptide derived from RET receptor tyrosine kinase (show RET ELISA Kits)

  9. DOK1 and DOK2 interact with the Tec protein tyrosine kinase (show TEC ELISA Kits).

  10. X-ray crystallographic models of the PTB (show PTBP1 ELISA Kits) domain of mouse dok1 protein

Human Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) interaction partners

  1. DOK1 was identified as a prognostic factor for non-metastatic CRC (show CALR ELISA Kits), and, via its drugability by PPARgamma (show PPARG ELISA Kits)-agonist, may constitute a potential target for future cancer treatments.

  2. DOK3 (show DOK3 ELISA Kits) expression was not altered much in HTLV-1-infected T cells.

  3. Results indicate that hypermethylation of tumor suppressor protein (show TP53 ELISA Kits) RASSF1A (show RASSF1 ELISA Kits) and docking protein 1 (DOK1) contributes to hepatocarcinogenesis and is associated to clinicopathological characteristics.

  4. Data show that residues Ser745 and Ser756 in the integrin beta2 tail, which are adjacent to the NxxF motif, are required for docking protein 1, docking protein 1, 62kDa (show GTF2H1 ELISA Kits) (downstream of tyrosine kinase 1) (Dok1) interaction.

  5. results support a model in which Dok1 phosphorylation normally suppresses localized Ras pathway activity in Crk (show CRK ELISA Kits)-transformed cells via recruitment and/or activation of RasGAP (show RASA1 ELISA Kits)

  6. Data implicate existence of alternate conformational states around the ligand binding pocket of the PTB (show PTBP1 ELISA Kits) domain of phosphoprotien Dok1 either in the native or in the near native conditions.

  7. Deregulation of DOK1 gene expression by EBV and novel insights into the regulation of the DOK1 tumor suppressor in viral-related carcinogenesis.

  8. point mutations in DOK1 and DOK2 genes are detected with low frequency in chronic myelomonocytic leukemia but may have consequences for the function of the DOK2 PTB (show PTBP1 ELISA Kits) domain

  9. A crucial role for DOK1 in the regulation of PDGF-BB-mediated tumour cell motility through a p130Cas-Rap1 signalling pathway.

  10. Taken together, these results reveal that Dok1 and Dok2 proteins are involved in an intrinsic negative feedback loop downstream of natural killer-cell-activating receptors in mouse and human.

DOK1 Antigen Profile

Antigen Summary

The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DOK1

  • ADP-ribosyltransferase 4 (Art4) antibody
  • docking protein 1 (Dok1) antibody
  • docking protein 1, 62kDa (downstream of tyrosine kinase 1) (DOK1) antibody
  • 4432404K01Rik antibody
  • ARTC4 antibody
  • AW557123 antibody
  • DO antibody
  • Dok-1 antibody
  • DOK1 antibody
  • P62DOK antibody

Protein level used designations for DOK1

ADP-ribosyltransferase C2 and C3 toxin-like 4 , NAD(P)(+)--arginine ADP-ribosyltransferase 4 , ecto-ADP-ribosyltransferase 4 , mono(ADP-ribosyl)transferase 4 , downstream of tyrosine kinase 1 , p62(dok) , downstream of tyrosine kinase-1 , Downstream of tyrosine kinase 1 , docking protein 1 , docking protein 1 (downstream of tyrosine kinase 1) , pp62

109978 Mus musculus
13448 Mus musculus
312477 Rattus norvegicus
1796 Homo sapiens
483100 Canis lupus familiaris
100233179 Sus scrofa
514962 Bos taurus
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