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anti-Doublecortin (DCX) Antibodies

DCX encodes a member of the doublecortin family. Additionally we are shipping Doublecortin Kits (36) and Doublecortin Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCX 1641 O43602
DCX 13193 O88809
DCX 84394  
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Top anti-Doublecortin Antibodies at

Showing 10 out of 157 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-DCX Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated WB WB Suggested Anti-DCX Antibody Titration: 0.2-1 ug/mlPositive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-DCX Antibody (S128) (ABIN389254) in K562 cell line lysates (35 µg/lane). DCX (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with DCX Antibody (S128) (ABIN389254), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using Doublecortin (Ab-376) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 ng), Blue: Antigen (100 ng) Figure 2: Flow cytometric analysis of SK-N-SH cells using DCX mouse mAb (green) and negative control (red) . 0.1 mg Log in to see 3 to 4 Days
Human Mouse Un-conjugated WB Western Blot analysis of DCX expression in transfected 293T cell line by DCX monoclonal antibody (M01), clone 1G12. Lane 1: DCX transfected lysate(41.4 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
Mouse Mouse Un-conjugated IF, WB Western blot analysis of Doublecortin on a mouse neonate lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-mouse Doublecortin antibody. 50 μg Log in to see 5 to 6 Days
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Mouse Goat Un-conjugated ELISA, WB Western Blot: Doublecortin Antibody [NBP2-26149] - NBP2-26149 (0.5ug/ml) staining of Mouse fetal Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days

DCX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Doublecortin Antibodies

  1. Human Monoclonal Doublecortin Primary Antibody for WB - ABIN393267 : Dijkmans, van Hooijdonk, Fitzsimons, Vreugdenhil: The doublecortin gene family and disorders of neuronal structure. in Central nervous system agents in medicinal chemistry 2010 (PubMed)
    Show all 5 references for ABIN393267

  2. Mouse (Murine) Monoclonal Doublecortin Primary Antibody for IF, WB - ABIN968637 : des Portes, Pinard, Billuart, Vinet, Koulakoff, Carrié, Gelot, Dupuis, Motte, Berwald-Netter, Catala, Kahn, Beldjord, Chelly: A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome. in Cell 1998 (PubMed)
    Show all 3 references for ABIN968637

  3. Human Polyclonal Doublecortin Primary Antibody for ELISA, WB - ABIN1533167 : Gleeson, Allen, Fox, Lamperti, Berkovic, Scheffer, Cooper, Dobyns, Minnerath, Ross, Walsh: Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein. in Cell 1998 (PubMed)
    Show all 3 references for ABIN1533167

  4. Chicken Polyclonal Doublecortin Primary Antibody for IHC, WB - ABIN2776750 : Zhang, Ryan, Di Cesare, Liu, Walsh, You: Doublecortin is expressed in articular chondrocytes. in Biochemical and biophysical research communications 2007 (PubMed)

  5. Mouse (Murine) Polyclonal Doublecortin Primary Antibody for ELISA, WB - ABIN4305985 : Klempin, Kronenberg, Cheung, Kettenmann, Kempermann: Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. in PLoS ONE 2011 (PubMed)

  6. Human Monoclonal Doublecortin Primary Antibody for ICC, FACS - ABIN969513 : Evangelisti, Florian, Massimi, Dominici, Giannini, Galardi, Buè, Massalini, McDowell, Messi, Gulino, Farace, Ciafrè: MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)

More Antibodies against Doublecortin Interaction Partners

Human Doublecortin (DCX) interaction partners

  1. From this family, we conclude that a DCX mutation causes a pleiotropic phenotype in the female even if X chromosome inactivation pattern is not skewed, and the novel missense mutation in DCX produced relatively mild dysfunction of the doublecortin protein.

  2. We identified a novel DCX mutation c.785A > G, p.Asp262Gly in a family with X-linked lissencephaly and subcortical band heterotopia

  3. In high-risk metastatic Neuroblastoma (show ARHGEF16 Antibodies), TH and DCX mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.

  4. Results point to a critical role of doublecortin in the formation of the neuromuscular junctions.

  5. DCX-positive cells occur in a wide range of hypothalamic nuclei in humans, mice and sheep.

  6. human DCX protein was expressed in human adipose stem cells, collagen II was decreased while aggrecan (show ACAN Antibodies), matrilin 2 (show MATN2 Antibodies), and GDF5 (show GDF5 Antibodies) were increased during the 14-day pellet culture.

  7. We propose that DCDC2 (show DCDC2 Antibodies) is a tumor suppressor gene of HCC (show FAM126A Antibodies).

  8. in utero doublecortin knockdown, but not knockout, shows a neocortical neuronal migration phenotype.

  9. Immunoblots revealed that depressed subjects displayed increased expression of doublecortin.

  10. coexpression of DCX and SPARC (show SPARC Antibodies) collaboratively diminished radioresistance of glioma cells.

Mouse (Murine) Doublecortin (DCX) interaction partners

  1. Dcx is a new marker for the Pax7 (show PAX7 Antibodies)(+)MyoD (show MYOD1 Antibodies)(-) subpopulation, which contributes to myofiber maturation during muscle regeneration.

  2. DCX-positive cells resembling immature and developing neurons were found in mice and sheep and human hypothalamus.

  3. we showed that miR (show MLXIP Antibodies)-29a directly regulated its target protein Doublecortin (DCX) expression, which further modulated axon branching in primary culture.

  4. Cdk5 (show CDK5 Antibodies) and its substrates, Dcx and p27kip1 (show CDKN1B Antibodies), regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.

  5. Doublecortin knockout mice show lamination defects of the hippocampal pyramidal cell layer largely restricted to the CA3 (show CA3 Antibodies) region.

  6. Dcx protein- and mRNA-levels reflected changes in neurogenesis

  7. DCX is dispensable for the development of new neurons in adult mice

  8. results indicate that immature DCX-expressing neurons are required for successful acquisition of spatial learning, as well as reversal learning, but are not necessary for the retrieval of stored long-term memories.

  9. In axons from mice mutant for Dcx, widespread differences are found in actin-associated proteins as compared with wild-type axons

  10. analysis of doublecortin expressing neurons in the adult mouse dentate gyrus

Doublecortin (DCX) Antigen Profile

Protein Summary

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Doublecortin (DCX) Antibodies

  • doublecortin (DCX) antibody
  • doublecortin (Dcx) antibody
  • 18C15.5 antibody
  • DBCN antibody
  • Dbct antibody
  • DC antibody
  • DCX antibody
  • LISX antibody
  • SCLH antibody
  • XLIS antibody

Protein level used designations for anti-Doublecortin (DCX) Antibodies

doublecortex; lissencephaly, X-linked (doublecortin) , doublecortin , doublecortex , doublin , lis-X , lissencephalin-X , neuronal migration protein doublecortin , lissencephaly, X-linked (doublecortin)

100058909 Equus caballus
494212 Felis catus
473733 Pan troglodytes
752002 Taeniopygia guttata
1641 Homo sapiens
13193 Mus musculus
84394 Rattus norvegicus
374242 Gallus gallus
787968 Bos taurus
612950 Canis lupus familiaris
100713827 Cavia porcellus
101109861 Ovis aries
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