Dual Specificity Phosphatase 1 (DUSP1) ELISA Kits

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. Additionally we are shipping DUSP1 Antibodies (109) and DUSP1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DUSP1 1843 P28562
DUSP1 19252 P28563
DUSP1 114856 Q64623
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Top DUSP1 ELISA Kits at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 12.2 pg/mL 31.25-2000 pg/mL 96 Tests Log in to see 13 to 16 Days
$589.47
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Mouse 13.2 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 15 to 17 Days
$929.89
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Chicken
  96 Tests Log in to see 15 to 18 Days
$707.14
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Monkey
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$707.14
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Sheep
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$707.14
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Guinea Pig
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$707.14
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Pig
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$707.14
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Dog
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Cow
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Rat
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More ELISA Kits for DUSP1 Interaction Partners

Human Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. The aim of this review is to shed light on the role of four different phosphatases (PTEN, PP2A (show PPP2R4 ELISA Kits), CDC25 (show RASGRF1 ELISA Kits) and DUSP1) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  2. Dual-specific phosphatase (DUSP1) was found to inhibit gallbladder cancer (GBC) cell proliferation, migration and invasion.

  3. The results presented here emphasize the importance of MKP-1 as a mediator of therapeutic effects of glucocorticoids in inflammatory lung diseases as well as its potential as a novel anti-inflammatory drug target.

  4. we show that IL-1 (show IL1A ELISA Kits) induces robust p38a (show MAPK14 ELISA Kits) activation both in the nucleus and in the cytoplasm/membrane.Following stimulation, p38a (show MAPK14 ELISA Kits) activity returns to a basal level in absence of receptor degradation. While nuclear pulse is controlled by MKP1 through a negative feedback to pp38, its basal activity is controlled by both TAB1 (show TAB1 ELISA Kits) and MKP1 through a positive feedback loop.

  5. Our results emphasize the importance of MKP-1 as a potential predictive biomarker for a subset of breast cancer patients with worse outcome and less susceptibility to treatment.

  6. Collectively, these data indicated that DUSP1 may induce the resistance against paclitaxel through the p38 MAPK (show MAPK14 ELISA Kits)-mediated overexpression of p-glycoprotein in human ovarian cancer cells.

  7. silencing of IL1B (show IL1B ELISA Kits) plus dexamethasone-induced DUSP1 significantly reduced IRF1 (show IRF1 ELISA Kits) expression. IL1B (show IL1B ELISA Kits)-induced expression of CXCL10 (show CXCL10 ELISA Kits) was largely insensitive to dexamethasone, whereas other DUSP1-enhanced, IRF1 (show IRF1 ELISA Kits)-dependent mRNAs showed various degrees of repression.

  8. dexamethasone-induced DUSP1 acts via p38 MAPK (show MAPK14 ELISA Kits) to switch on the mRNA destabilizing function of protein-tristetraprolin (show ZFP36 ELISA Kits) to repress pro-inflammatory cytokine secretion from ASM (show SMPD1 ELISA Kits) cells

  9. LPS (show IRF6 ELISA Kits) tolerance interferes with TLR4 (show TLR4 ELISA Kits) signaling by inhibiting Lyn (show LYN ELISA Kits) and c-Src (show SRC ELISA Kits) phosphorylation and their recruitment to TLR4 (show TLR4 ELISA Kits), while increasing the phosphatase activity and expression of PP2A (show PPP2R4 ELISA Kits), PTPN22 (show PTPN22 ELISA Kits), PTP1B (show PTPN1 ELISA Kits) and MKP1.

  10. This study shows that RIG-I (show DDX58 ELISA Kits) activation results in MKP-1-mediated inhibition of cell proliferation in melanoma cells via controlling the p38 (show CRK ELISA Kits)-HSP27 (show HSPB1 ELISA Kits), c-Jun (show JUN ELISA Kits) and rpS6 (show RPS6 ELISA Kits) pathways

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. c-FOS and DUSP1 expression levels determine the threshold of tyrosine kinase (show TYRO3 ELISA Kits) inhibitor (TKI) efficacy, such that growth-factor-induced expression of c-FOS and DUSP1 confers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias.

  2. PTHrP (show PTHLH ELISA Kits) counteracts the pro-apoptotic actions of reactive oxygen species by a mechanism dependent on MKP1-induced dephosphorylation.

  3. A2AR (show ADORA2A ELISA Kits) signaling regulates both basal and LPS (show TLR4 ELISA Kits)-induced DUSP1 levels in macrophages via activating the adenylate cyclase pathway.

  4. these data suggest an important role for DUSPs in regulating MAPK (show MAPK1 ELISA Kits) dephosphorylation, with an emphasis on DUSP1, during early adipogenesis

  5. Loss of DUSP1 does not cause changes in cartilage degeneration and gait in a mouse model of spontaneous osteoarthritis at 21 months of age.

  6. Nr4a1 (show NR4A1 ELISA Kits) induction is dependent on ERK1/2 (show MAPK1/3 ELISA Kits) and that MKP-1 negatively regulates this induction.

  7. MKP-1 negatively regulates chemokine (show CCL1 ELISA Kits)-driven osteoclast formation and subsequent bone resorption in response to LPS (show TLR4 ELISA Kits) stimulation

  8. results suggest that the p38alpha (show MAPK14 ELISA Kits)-MKP-1 signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.

  9. DUSP1 and tristetraprolin (show ZFP36 ELISA Kits) cooperate to regulate macrophage responses to lipopolysaccharide.

  10. MKP-1 regulated the expression of MMP-12 (show MMP12 ELISA Kits).

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2 (show MAPK1/3 ELISA Kits)-mediated aldosterone production in response to the hormone.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) interaction partners

  1. Agonist stimulation of vascular smooth muscle increases PKC (show FYN ELISA Kits) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (show MAPK1 ELISA Kits) activity at submaximal values.

DUSP1 Antigen Profile

Antigen Summary

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Gene names and symbols associated with DUSP1

  • dual specificity phosphatase 1 (DUSP1) antibody
  • dual specificity phosphatase 1 (dusp1) antibody
  • dual specificity phosphatase 1 (Dusp1) antibody
  • 3CH134 antibody
  • cb269 antibody
  • CL100 antibody
  • DUSP1 antibody
  • erp antibody
  • HVH1 antibody
  • id:ibd2586 antibody
  • mkp-1 antibody
  • Mkp1 antibody
  • PTPN10 antibody
  • Ptpn16 antibody
  • sb:cb269 antibody
  • U19515 antibody
  • wu:fd19g02 antibody
  • wu:fe50g09 antibody
  • zgc:55920 antibody

Protein level used designations for DUSP1

dual specificity protein phosphatase 1 , dual specificity phosphatase 1 , mkp-1 , MAP kinase phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , mitogen-activated protein kinase phosphatase-1 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , MAPK phosphatase 1

GENE ID SPECIES
374192 Gallus gallus
471742 Pan troglodytes
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
406340 Danio rerio
1843 Homo sapiens
19252 Mus musculus
114856 Rattus norvegicus
489117 Canis lupus familiaris
539175 Bos taurus
100522469 Sus scrofa
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