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Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping.
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Ankyrin-B then interacts with dynactin-4 (show DCTN5 Proteins) and dystrophin (show DMD Proteins), whereas dynactin-4 (show DCTN5 Proteins) collaborates with dystrophin (show DMD Proteins) in coordinating costamere-aligned microtubules
Findings provide evidence that DCTN4 missense variants, especially p.Tyr263Cys, may be involved in the pathogenesis of chronic Pseudomonas aeruginosa infection in male with cystic fi brosis.
used an extreme phenotype study to discover that variants in DCTN4, encoding a dynactin (show DCTN1 Proteins) protein, are associated with time to first P. aeruginosa airway infection, chronic P. aeruginosa infection and mucoid P. aeruginosa in individuals with cystic fibrosis (show S100A8 Proteins)
ATP7B (show ATP7B Proteins) interaction with p62 (show GTF2H1 Proteins) is a key component of the copper-induced trafficking pathway that delivers ATP7B (show ATP7B Proteins) to subapical vesicles of hepatocytes for the removal of excess copper into bile
Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.
dynactin subunit 5
, dynactin 4
, dynactin 4 (p62)
, dynactin 5 (p25)
, dynactin subunit 4
, dynactin 4 (p62) isoform 1
, dynactin 4 (p62) isoform 2
, dynactin subunit p62
, dynactin subunit 4-like
, dynactin p62 subunit