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anti-Exostosin 2 (EXT2) Antibodies

EXT2 encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Additionally we are shipping EXT2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse EXT2 EXT2 14043 P70428
EXT2 2132 Q93063
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Top anti-EXT2 Antibodies at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometry analysis of Hela cells using EXT2 Antibody (Center) Cat.-No AP51484PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of EXT2 Antibody (Center) Cat.-No AP51484PU-N with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A549 B: Hela 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details

EXT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Top referenced anti-EXT2 Antibodies

  1. Human Polyclonal EXT2 Primary Antibody for EIA, FACS - ABIN952145 : Zhao, Bradfield, Zhang, Annaiah, Wang, Kim, Glessner, Frackelton, Otieno, Doran, Thomas, Garris, Hou, Chiavacci, Li, Berkowitz, Hakonarson, Grant: Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI. in Diabetes 2010 (PubMed)
    Show all 5 references for ABIN952145

More Antibodies against EXT2 Interaction Partners

Mouse (Murine) Exostosin 2 (EXT2) interaction partners

  1. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  2. The study indicates that formation of stereotypic exostoses requires a significant, but not complete, loss of Ext expression.

  3. The EXT2 gene encodes an essential component of the glycosyltransferase (show GTDC2 Antibodies) complex required for biosynthesis of heparan sulfate, which may eventually modulate the signaling involved in bone formation

  4. EXT2 peaks during early postnatal period in the cerebrum and around birth in the cerebellum. EXT2 was localized primarily in the neuroepithelial cells surrounding the lateral ventricles, the mesencephalic vesicle, and the fourth ventricle.

  5. NDST1 competes with EXT1 for binding to EXT2.

Human Exostosin 2 (EXT2) interaction partners

  1. We found that the prevalence of EXT1 mutations was greater than that of EXT2 mutations in Japanese multiple osteochondromas families.

  2. EXT2 gene might not have a major role in the development of type 2 diabetes in the Chinese population.

  3. EXT2 mutation is associated with multiple osteochondromatosis.

  4. Heterozygous loss of function of EXT1 and EXT2 results in a decreased arteriolar endothelial glycocalyx but improved flow mediated vasodilation.

  5. loss of function of EXT2 subjects with hereditary multiple exostoses affects pancreatic insulin (show INS Antibodies) secretion capacity and development.

  6. Analysis of microsatellite polymorphic markers in the 11p region harboring the EXT2 gene did not reveal any loss of heterozygosity

  7. The heterozygous mutation c.743+1G>A in the EXT2 gene causes HME as a result of abnormal splicing, mRNA decay, and the resulting haploinsufficiency of EXT2.

  8. EXT1 and EXT2 heterozygous mutations in 18 (54.6 %) and ten (30.3 %) probands respectively, which represents a total of 28 (84.9 %) index cases.

  9. The second exon of EXT2. A c.244delG mutation is associated with hereditary multiple exostosis.

  10. This study demonstrated no association of rs1113132, rs3740878 and rs11037909 EXT2 variants with type 2 diabetes mellitus.

EXT2 Antigen Profile

Protein Summary

This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with anti-Exostosin 2 (EXT2) Antibodies

  • exostoses (multiple) 2 (Ext2) antibody
  • exostosin 2 (EXT2) antibody
  • exostosin glycosyltransferase 2 (EXT2) antibody
  • AI893565 antibody
  • SOTV antibody

Protein level used designations for anti-Exostosin 2 (EXT2) Antibodies

exostosin-2 , glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase , multiple exostoses protein 2 homolog , HS-POL , HS-polymerase , exostoses (multiple) 2 , glucuronyl/N-acetylglucosaminyl transferase , N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase , multiple exostoses protein 2 , putative tumor suppressor protein EXT2

GENE ID SPECIES
14043 Mus musculus
281151 Bos taurus
2132 Homo sapiens
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