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EXOSC2 Antibodies

(Exosome Component 2 (EXOSC2))
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC2 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC4 and EXOSC7.
EXOSC2 antibody  (N-Term) EXOSC2 antibody  (N-Term) EXOSC2 antibody (N-Term) (ABIN2779057)

EXOSC2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit IHC, WB Host: Rabbit Polyclonal unconjugated

EXOSC2 antibody  (Middle Region) EXOSC2 antibody  (Middle Region) EXOSC2 antibody (Middle Region) (ABIN2779056)

EXOSC2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated

EXOSC2 antibody  (AA 71-160) EXOSC2 antibody  (AA 71-160) EXOSC2 antibody (AA 71-160) (ABIN565068)

EXOSC2 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated

EXOSC2 Antibodies by Reactivity

Find EXOSC2 Antibodies for a variety of species such as anti-Human EXOSC2, anti-Mouse EXOSC2, anti-Dog EXOSC2. The species listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 Antibodies by Application

Find EXOSC2 Antibodies validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

EXOSC2 Antibodies by Host

Find EXOSC2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 Antibodies by Binding Specificity

Find EXOSC2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

EXOSC2 Antibodies by Clonality

Find available monoclonal or polyclonal EXOSC2 Antibodies. Click on a link to go to the corresponding products.

EXOSC2 Antibodies by Clone

Find EXOSC2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

Popular EXOSC2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN633278
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1881328
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Guinea Pig, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN202179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
  • (1)
Cat. No. ABIN525144
Quantity 100 μg
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6740694
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7114010
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6998760
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7114011
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
Cat. No. ABIN7133432
Quantity 150 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN2772339
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN2600842
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Human, Mouse, Pig, Xenopus laevis
Application IP, WB
Validations
Cat. No. ABIN1894319
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application DB
Validations
Cat. No. ABIN1831959
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN2600840
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF/ICC, IHC, IP, WB
Validations
Cat. No. ABIN6332962
Quantity 1 mL
Datasheet Datasheet

Latest Publications for our EXOSC2 Antibodies

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Humphray, Oliver, Hunt, Plumb, Loveland, Howe, Andrews, Searle, Hunt, Scott, Jones, Ainscough, Almeida, Ambrose, Ashwell, Babbage, Babbage, Bagguley, Bailey, Banerjee, Barker, Barlow, Bates, Beasley et al.: "DNA sequence and analysis of human chromosome 9. ..." in: Nature, Vol. 429, Issue 6990, pp. 369-74, (2004) (PubMed).

Mitchell, Petfalski, Shevchenko, Mann, Tollervey: "The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases." in: Cell, Vol. 91, Issue 4, pp. 457-66, (1997) (PubMed).

Aliases for EXOSC2 Antibodies

exosome component 2 (EXOSC2) Antibodies
exosome component 2 (exosc2) Antibodies
exosome component 2 (Bm1_33895) Antibodies
exosome component 2 (PTRG_00114) Antibodies
exosome component 2 (Exosc2) Antibodies
exosome component 2 L homeolog (exosc2.L) Antibodies
EXOSC2 Antibodies
exosc2 Antibodies
fa97b01 Antibodies
hRrp4p Antibodies
MGC97533 Antibodies
p7 Antibodies
RRP4 Antibodies
Rrp4 Antibodies
Rrp4p Antibodies
wu:fa97b01 Antibodies
zgc:110117 Antibodies
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