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The protein encoded by FOLR1 is a member of the folate receptor family. Additionally we are shipping Folate Receptor 1 (Adult) Proteins (25) and Folate Receptor 1 (Adult) Kits (23) and many more products for this protein.
Showing 10 out of 129 products:
Human Polyclonal FOLR1 Primary Antibody for EIA, FACS - ABIN952351
Sivakumaran, Zhang, Kelley, Gonit, Hao, Ratnam: Androgen activation of the folate receptor α gene through partial tethering of the androgen receptor by C/EBPα. in The Journal of steroid biochemistry and molecular biology 2010
Show all 3 references for ABIN952351
Human Monoclonal FOLR1 Primary Antibody for EIA - ABIN112586
Henderson: Folate-binding proteins. in Annual review of nutrition 1990
Show all 2 references for ABIN112586
Human Polyclonal FOLR1 Primary Antibody for ICC, IF - ABIN442264
Werner, Karve, Sukumar, Cummings, Copp, Chen, Zhang, Wang: Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis. in Biomaterials 2011
Show all 2 references for ABIN442264
Human Polyclonal FOLR1 Primary Antibody for WB - ABIN2776804
Iwakiri, Sonobe, Nagai, Hirata, Wada, Miyahara: Expression status of folate receptor alpha is significantly correlated with prognosis in non-small-cell lung cancers. in Annals of surgical oncology 2008
Show all 2 references for ABIN2776804
Human Polyclonal FOLR1 Primary Antibody for FACS, IHC (p) - ABIN654650
Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010
This study presented the disintegration of folate from bovine FOLR1 during high temperature processing.
summarizes recent biochemical, analytical, food science, and nutritional advances regarding folate-binding protein (show GNMT Antibodies) in milk [REVIEW]
ligand binding characteristics and aggregation behavior depends on the presence of amphiphatic substances [folate binding protein (show GNMT Antibodies)]
FOLR1 is a key regulatory point of folate metabolism for milk protein (show CSN2 Antibodies) synthesis within mammary epithelial cells.
Suppression of FOLR1 by RNA interference altered gene expression profile of taxol-resistant nasopharyngeal carcinoma cells. Apoptosis-related genes, gene alterations in viral carcinogenesis/MAPK (show MAPK1 Antibodies) pathways may be important for taxol resistance reversal.
we confirmed the similarities between epithelial ovarian cancer and fallopian tube, normal and adenocarcinoma using FOLR1, FOLR2 (show FOLR2 Antibodies), CD68 (show CD68 Antibodies) and CD11b (show ITGAM Antibodies) markers
Suggest RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor-alpha.
Folate receptor (show FOLR3 Antibodies) expression on murine and human adipose tissue macrophages
Findings suggest the clinical development of IMGN853 as a novel targeted therapy for patients with folate receptor alpha (FRalpha)-expressing tumors.
triple negative/basal tumors were significantly associated with increased expression of FOLR1 mRNA, compared to ER+ and HER2 (show ERBB2 Antibodies)+ tumors.
Molecular dynamic simulation of the binding process of folic acid to folate receptor alpha
Studies indicate folate receptor (show FOLR3 Antibodies) (FR) as a prognostic biomarker for ovarian cancer.
The overexpression of folate receptor alpha mRNA was associated with growth of pituitary adenomas.
this is the first study to simultaneously evaluate both DNA methylation (show HELLS Antibodies) and protein expression of all three folate transporter genes, FOLR1, PCFT (show SLC46A1 Antibodies), and RFC1 (show RFC1 Antibodies), in colorectal cancer.
Quantitative RT-PCR showed that Slc19a1 (show SLC19A1 Antibodies) mRNA was expressed in mouse cumulus-oocyte complexes (COCs) and oocytes, whereas Folr1 showed expression only in preimplantation embryos, increasing from the 2-cell stage onward.
under conditions of reduced folate (Folr-/-) signalling, pathways crucial for proper development of the neural tube are significantly altered.
Nesting of T helper cell epitopes results in recruitment of latent pools of naive high-affinity/avidity folate receptor (show FOLR3 Antibodies) (FR)alpha-specific T cells, which have the ability to home to tumors expressing FRalpha and to reduce tumor burden.
Fbp1 (show FBP2 Antibodies) has a role in anterior neural tube closure
Abnormal heart looping was observed during early development of Folr1(-/-) embryos partially rescued by maternal folinic acid supplementation.
folate receptor (show FOLR3 Antibodies) type beta is induced in a bone marrow engraftment model of acute myelogenous leukemia
Folr1 gene ablation and abnormal folate homeostasis altered gene expression in developing heart and conotruncal tissues
These findings findings suggest that FRalpha plays a role in pituitary tumor formation, and this effect may in part be due to its regulation of the NOTCH3 (show NOTCH3 Antibodies) pathway.
FOLR1 is a target for regulation by HNF4-alpha (show HNF4A Antibodies) in visceral endoderm.
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
folate receptor alpha
, erythroid-specific folate receptor
, membrane-bound folate binding protein
, folate receptor 1 (adult)
, Folate receptor alpha
, milk folate-binding protein
, KB cells FBP
, adult folate-binding protein
, folate binding protein
, folate receptor, adult
, ovarian tumor-associated antigen MOv18
, folate binding protein 1
, folate-binding protein 1