FOLR1 antibody (N-Term)

Catalog No. ABIN654650

The Rabbit Polyclonal anti-FOLR1 antibody is suitable to detect FOLR1 in samples from Human. It has been validated for WB, FACS and IHC (p).

Quick Overview for FOLR1 antibody (N-Term) (ABIN654650)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB28535

Product Details anti-FOLR1 Antibody

Binding Specificity: AA 33-68, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P-Leica: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1

Background: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 29819

Gene ID: 2348

NCBI Accession: NP_000793, NP_057936, NP_057937, NP_057941

UniProt: P15328

Pathways: Dicarboxylic Acid Transport